📰 GPCR Weekly News, May 22 to 28, 2023
Hi GPCR lovers👋, Ready for exciting news in the GPCR world? Read them below!
You can now watch the live talk recordings from the previous symposiums, check them out here.
Also, let's congratulate Lauri Urvas on his first first-author paper! Check out GPCR papers featuring Drs. Bryan Roth, Peter Gmeiner, and Thomas P. Sakmar this week.
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Below is your Classified GPCR News at a glance for May 22 to 28, 2023.
GPCR Activation and Signaling
The adhesion GPCRs CELSR1-3 and LPHN3 engage G proteins via distinct activation mechanisms.
Modulating GPCR and 14-3-3 protein interactions: prospects for CNS drug discovery.
GPCR Binders, Drugs, and more
GPCRs in Cardiology, Endocrinology, and Taste
GPCRs in Neuroscience
PACAP key interactions with PAC1, VPAC1, and VPAC2 identified by molecular dynamics simulations.
Therapeutic antagonism of the neurokinin 1 receptor in endosomes provides sustained pain relief.
Structural and Molecular Insights into GPCR Function
A key GPCR phosphorylation motif discovered in arrestin2â‹…CCR5 phosphopeptide complexes.
Divergent regulation of α-arrestin ARRDC3 function by ubiquitination.
Industry News
GPCR Events, Meetings, and Webinars
The Illuminating the Understudied Druggable Proteome Conference. (June 4 - 8, 2023).
2023 Molecular Pharmacology (GRS) Seminar GRC. (June 10 - 11, 2023).
NEW GPCRs in drug discovery: challenges & solutions (June 19 - 23, 2023)
Training School on “Cell-based assays to study Adhesion GPCR function". (June 28 - 30, 2023)
FREE 11th Adrenoceptor Symposium: Adrenoceptors and GPCR Signalling (June 30 - July 1, 2023)
19th World Congress of Basic & Clinical Pharmacology 2023. (July 2 - 7, 2023).