📰 GPCR Weekly News, May 29 to June 4, 2023
Hello GPCR friends👋, Stay informed with the latest developments in GPCR research and industry news! Happy reading📚!
This week, we would like to highlight two new publications:
Our next Dr. GPCR Symposium is coming up on July 21st on Structural and Molecular Insights on GPCR Activation. We are looking for speakers and poster presenters! If you'd like to showcase your work, please email us at Hello@DrGPCR.com. For more information, follow the Dr. GPCR News by subscribing to our monthly newsletter.
We look forward to seeing you in a few days at the Molecular Pharmacology GRC and the associated Molecular Pharmacology GRS in Switzerland. We would also like to take a moment to thank the organizers for inviting Dr. Yamina Berchiche, our founder.
Below is your Classified GPCR News at a glance for May 29th to June 4th, 2023.
GPCR Activation and Signaling
Therapeutic antagonism of the neurokinin 1 receptor in endosomes provides sustained pain relief.
Gβγ signaling regulates microtubule-dependent control of Golgi integrity.
Ligand-dependent intracellular trafficking of the G protein-coupled P2Y6 receptor.
GPCR Binders, Drugs, and more
GPCRs in Cardiology, Endocrinology, and Taste
GPR97 deficiency ameliorates renal interstitial fibrosis in mouse hypertensive nephropathy.
Bitter Odorants and Odorous Bitters: Toxicity and Human TAS2R Targets.
GPCRs in Neuroscience
GPCRs in Oncology and Immunology
Methods & Updates in GPCR Research
Activity Models of Key GPCR Families in the Central Nervous System: A Tool for Many Purposes.
Structure-based pharmacophore modeling 1. Automated random pharmacophore model generation.
How can we improve the measurement of receptor signaling bias?
Reviews, GPCRs, and more
Advancements in G protein-coupled receptor biosensors to study GPCR-G protein coupling.
Application of computational methods for class A GPCR Ligand discovery.
Targeting biased signaling by PAR1: function and molecular mechanism of parmodulins.
Lysophosphatidic acid, a simple phospholipid with myriad functions.
Structural and Molecular Insights into GPCR Function
The role of G protein conformation in receptor-G protein selectivity.
New insights into GPCR coupling and dimerisation from cryo-EM structures.
Industry News
Domain Therapeutics' Nomination of DT-9045: A Groundbreaking NAM for Immunooncology
Structure Therapeutics to Present at Jefferies Healthcare Conference
GPCR Events, Meetings, and Webinars
GPCRs in drug discovery: challenges & solutions (June 19 - 23, 2023)
Training School on “Cell-based assays to study Adhesion GPCR function". (June 28 - 30, 2023)
FREE 11th Adrenoceptor Symposium: Adrenoceptors and GPCR Signalling (June 30 - July 1, 2023)
19th World Congress of Basic & Clinical Pharmacology 2023. (July 2 - 7, 2023).