📰 GPCR Weekly News, October 2 to 8, 2023

Hello GPCR people! Check out our GPCR roundup now, and be the first to read!

This week's highlight:

• Congrats to our partner GPCR Therapeutics, on their expansion into fibrosis with their new research.

Save the dates:

• November 2 - 4: We're sponsoring the GPCR Retreat and would love to meet you there! Join the waitlist by emailing gpcrretreat@uottawa.ca. Submit a logo design by Nov 1st on the Logo Contest page. No registration is needed to submit your logo design.

Subscribe now to Dr. GPCR Newsletter to get more info!

Check out the weekly Classified GPCR News from October 2nd to 8th, 2023.

GPCR Binders, Drugs, and more

• In silico identification of a biarylamine acting as agonist at human β3 adrenoceptors and exerting BRL37344-like effects on mouse metabolism

• Development, synthesis and evaluation of novel fluorescent Endothelin-B receptor probes

GPCRs in Cardiology, Endocrinology, and Taste

• GPRASP1 loss-of-function links to arteriovenous malformations by endothelial activating GPR4 signals

GPCRs in Neuroscience

• Involvement of a silkworm D2-like dopamine receptor in the promotion of feeding and related behaviors

Methods & Updates in GPCR Research

• Functional GPCR expression in eukaryotic LEXSY system

Structural and Molecular Insights into GPCR Function

• Interplay of Cholesterol and Actin in Neurotransmitter GPCR Signaling: Insights from Chronic Cholesterol Depletion Using Statin

• Side-Chain Dynamics of the α1B -Adrenergic Receptor determined by NMR via Methyl Relaxation

• Structural determinants of sphingosine-1-phosphate receptor selectivity

Industry News

• Sosei Heptares and Verily Nominate First G-protein-coupled receptor Target for Therapeutic Development

• DKK 25 million to development of databases supporting medical research

• ‘Define your own success’: Duke leaders talk success, failure at symposium honoring Nobel Laureate Robert Lefkowitz

• Integral Molecular Secures Nearly $900K in NIH Funding to Discover Antibodies Against Difficult and Conserved Protein Targets

• GPCR Therapeutics Expands Pipeline into Fibrosis with a Combination Approach Targeting LPA1

GPCR Events, Meetings, and Webinars

• October 25 - 27, 2023 | 3rd Annual Meeting IRN I-GPCRNet

• November 2 - 4, 2023 | GPCR Retreat- Registration Closed

• November 15 - 17, 2023 | MPGPCR Conference

• November 20 - 23, 2023 | ASCEPT Annual Scientific Meeting

• February 3 - 7, 2024 | SLAS2024 International Conference and Exhibition

• March 23 - 24, 2024 | Ligand Recognition and Molecular Gating Seminar

• March 24 - 29, 2024 | Ligand Recognition and Molecular Gating Conference

• April 5 - 10, 2024 | AACR Annual Meeting

• May 13 - 17, 2024 | 20th Annual PEGS Boston Summit

• May 16 - 19, 2024 | ASPET 2024

• May 27 - 29, 2024 | SLAS Europe 2024 Conference and Exhibition

• June 2 - 4, 2024 | Chemotactic Cytokines

GPCR Jobs

• NEW Senior Scientist, In vitro pharmacology - Crinetics Pharmaceuticals

• NEW Senior Director, In vitro pharmacology - Crinetics Pharmaceuticals

• In vivo Antibody Discovery Research Scientist

• In Vitro Biologist/Molecular Pharmacologist

• Senior Vice President, Oncology Clinical Research

• Scientist (level I or II)

• Research Fellow

• Research Technician II - Surgery

• Post-Doc Research Associate

• Research Technician

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