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Results found for "Family B GPCRs"
- TAS2R supports odontoblastic differentiation of human dental pulp stem cells in the inflammatory...
The expression markers related to odontoblastic differentiation of hDPSCs were observed by qPCR and chemical The G protein and intracellular Ca2+ were detected, respectively, by qPCR and Fluo-4AM Ca2+ fluorescent Read more at the source #DrGPCR #GPCR #IndustryNews
- MSX-122: Is an effective small molecule CXCR4 antagonist in cancer therapy?
C-X-C motif chemokine receptor 4 (CXCR4), a G-protein-coupled receptor (GPCR), has one identified natural Read more at the source #DrGPCR #GPCR #IndustryNews
- A correlation study of adhesion G protein-coupled receptors as potential therapeutic targets in...
therapeutic targets in Uterine Corpus Endometrial cancer "Adhesion G protein-coupled receptors (adhesion GPCRs ), as a member of the G protein-coupled receptors (GPCRs) superfamily, have gradually entered the field The structure, function, and involvement of adhesion GPCRs in cancer development have been discussed alsooneofthemostcommonfemalereproductivesystemtumors, but there are few pieces of research related to adhesion GPCRs Read more at the source #DrGPCR #GPCR #IndustryNews
- Helix 8 in chemotactic receptors of the complement system
crystal structures of inactive C5aR1 in terms of an inverted orientation of helix H8, unobserved in other GPCR Read more at the source #DrGPCR #GPCR #IndustryNews
- Dopamine D 1 receptor-mediated β-arrestin signaling: Insight from pharmacology, biology, behavior...
A major pan-receptor focus has been to identify GPCR-selective ligands that have bias in G protein-dependent Read more at the source #DrGPCR #GPCR #IndustryNews
- Signaling pathways activated by sea bass gonadotropin-inhibitory hormone peptides in COS-7 cells...
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- Upregulation of Phospholipase C Gene Expression Due to Norepinephrine-Induced Hypertrophic Response
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- Fentanyl activates ovarian cancer and alleviates chemotherapy-induced toxicity via opioid...
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- Chemerin Forms: Their Generation and Activity
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- Neurotransmitters: Potential Targets in Glioblastoma
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- Structure of the human galanin receptor 2 bound to galanin and Gq reveals the basis of ligand...
Three G-protein coupled receptors (GPCRs) for galanin have been discovered, which is the focus of efforts Read more at the source #DrGPCR #GPCR #IndustryNews
- Platelets in the NETworks interweaving inflammation and thrombosis
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- Structure of Mycobacterium tuberculosis Cya, an evolutionary ancestor of the mammalian membrane...
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- Ginsenoside Rg5 allosterically interacts with P2RY12 and ameliorates deep venous thrombosis by...
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- C5aR2 receptor: The genomic twin of the flamboyant C5aR1
The C5aR1 is a classical G-protein-coupled receptor (GPCR), whereas C5aR2 is a nonclassical GPCR that Read more at the source #DrGPCR #GPCR #IndustryNews
- C1-inhibitor influence on platelet activation by thrombin receptors agonists
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- Microbial Metabolites Orchestrate a Distinct Multi-Tiered Regulatory Network in the Intestinal Epith
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- Molecular mechanism of allosteric modulation for the cannabinoid receptor CB1
September 2022 "Given the promising clinical value of allosteric modulators of G protein-coupled-receptors (GPCRs ), mechanistic understanding of how these modulators alter GPCR function is of significance. Read more at the source #DrGPCR #GPCR #IndustryNews
- FSH and bone: Comparison between males with central versus primary hypogonadism
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- Computational study of the conformational ensemble of CX3C chemokine receptor 1 (CX3CR1) and its...
ligands "The CX3C chemokine receptor 1 (CX3CR1), a member of the class A of G Protein-Coupled Receptors (GPCR patterns that characterize a functional state to contribute to the understanding of the complexity of the GPCR Read more at the source #DrGPCR #GPCR #IndustryNews
- Propranolol: A “Pick and Roll” Team Player in Benign Tumors and Cancer Therapies
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- A central alarm system that gates multi-sensory innate threat cues to the amygdala
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- Regulation of rod photoreceptor function by farnesylated G-protein γ-subunits
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- Induced Human Regulatory T Cells Express the Glucagon-like Peptide-1 Receptor
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- C3aR plays both sides in regulating resistance to bacterial infections
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- Identification and functional characterization of the sulfakinin and sulfakinin receptor in the...
physiological functions in invertebrates through the interaction with G-protein-coupled receptors (GPCRs Read more at the source #DrGPCR #GPCR #IndustryNews
- Sweet taste receptor agonists attenuate macrophage IL‐1β expression and eosinophilic inflammation...
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- Identification of hub genes in the subacute spinal cord injury in rats
Finally, the relative mRNA expression level of central genes was verified by RT-PCR." Read more at the source #DrGPCR #GPCR #IndustryNews
- Immunomodulatory Role of Neuropeptides in the Cornea
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- Dynamics of tumor-associated macrophages in a quantitative systems pharmacology model of...
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