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Results found for "GPCR-RAMP interactions"
- Targeted Therapies to Reduce Side Effects in Modern Drug Development
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- Addex and Indivior Extend GABAB Positive Allosteric Modulator Research Collaboration for...
compounds for Charcot-Marie-Tooth type 1A neuropathy (CMT1A) and pain. " Read more at the source #DrGPCR #GPCR
- Karuna Therapeutics Announces Positive Results from Phase 3 EMERGENT-2 Trial of KarXT in...
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- Regulation of rod photoreceptor function by farnesylated G-protein γ-subunits
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- Domain Therapeutics Raises $42m Series A Financing
specializing in the research and development of innovative drugs targeting G Protein-Coupled Receptors (GPCRs Read more at the source #DrGPCR #GPCR #IndustryNews
- Cancer Research UK and Sosei Heptares sign agreement to advance cancer immunotherapy candidate ...
Corporation (“the Company”; TSE: 4565), an international biopharmaceutical company and world-leader in GPCR1 Read more at the source #DrGPCR #GPCR #IndustryNews
- Effects of Small Molecule Ligands on ACKR3 Receptors
SIGNIFICANCE STATEMENT: We are interested in the signaling produced by the G protein coupled receptor In this study, novel selective ligands for ACKR3 were discovered and the site of interactions between Read more at the source #DrGPCR #GPCR #IndustryNews
- β2-Adrenergic Receptor Expression and Intracellular Signaling in B Cells Are Highly Dynamic during..
receptor kinase 2 (GRK-2), β-Arrestin 2, p38 MAPK, extracellular signal-regulated kinase 1/2 (ERK1/2) and cAMP Read more at the source #DrGPCR #GPCR #IndustryNews
- Domain Therapeutics and Explicyte enter partnership agreement in immuno-oncology
March 2022 "Explicyte grants Domain Therapeutics exclusivity on data related to GPCR implicated in immunoresistance company specializing in the discovery and development of new drugs targeting G Protein-Coupled Receptors (GPCRs The two companies will combine their expertise to identify GPCR targets and associated biomarkers to Read more at the source #DrGPCR #GPCR #IndustryNews
- Third Rock pushes newest fund over $1B line as it marks 15 years in venture capital
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- Michel Bouvier appointed Knight of the Ordre national du Québec
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- Crinetics Presents Clinical And Research Results At ENDO 2022
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- Addex raises $4.2 million in equity financing
issuance and will expire five years from their date of issuance. " Read more at the source #DrGPCR #GPCR
- Design Pharmaceuticals Closes $5 Million Pre-series A Round to Accelerate Commercialization of ...
These molecules are then evaluated at unprecedented speed and scale on hundreds of GPCR targets simultaneously Read more at the source #DrGPCR #GPCR #IndustryNews
- ShouTi Pharma CEO Dr. Raymond Stevens was interviewed by Moira Gunn of the NPR TechNation podcast
April 2022 Read more at the source #DrGPCR #GPCR #IndustryNews
- Sosei Heptares Confirms Senior Leadership Changes to Drive the Company Through the Next Stage ...
Changes to Drive the Company Through the Next Stage of its Evolution "New team focused on expanding its GPCR-focused Read more at the source #DrGPCR #GPCR #IndustryNews
- Novel interaction between neurotrophic factor-α1/carboxypeptidase E and serotonin receptor, 5-HTR1E,
We uncovered a novel neuroprotective mechanism involving interaction between neurotrophic factor-α1 ( Co-immunoprecipitation and pull-down assays confirmed interaction between NFα1/CPE and 5-HTR1E and 125I Molecular dynamics studies revealed that NF-α1/CPE interacts with 5-HTR1E via 3 salt bridges, stabilized Thus, NF-α1/CPE uniquely interacts with serotonin receptor 5-HTR1E to activate the β-arrestin/ERK/CREB
- John Streicher talks about his work on terpenes found in cannabis as these may be a novel way to ...
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- Confo Therapeutics Doses First Subjects In Phase 1 Clinical Trial Of CFTX-1554 For The Treatment ...
– Confo Therapeutics, a leader in the discovery of medicines targeting G-protein coupled receptors (GPCRs pharmacokinetics of CFTX-1554 in healthy subjects (NCT05260658). " Read more at the source #DrGPCR #GPCR
- Modulation of Striatal Adenosinergic Function by HTL0041178, a Selective GPR52 Agonist
control neuropsychiatric symptoms in conditions such as schizophrenia. " Read more at the source #DrGPCR #GPCR
- Trevena Receives up to $40M in OLINVYK ex-US Royalty-Based Financing from R-Bridge Healthcare ...
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- Inversago Pharma appoints Glenn S. Vraniak as Chief Financial Officer
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- Trevena Announces Receipt of First $15 million Tranche in Connection with its $40 million ...
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- Applying Allosteric Modulator Pharmacology to Treat Dyskinesia and Other Movement Disorders with ...
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- Crinetics Pharmaceuticals Announces Pricing Of Underwritten Common Stock Offering
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- Addex Therapeutics Completes Patient Enrollment For Dipraglurant Blepharospasm Phase 2 Clinical ...
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- Addex Expands Pipeline With Selective M4 Positive Allosteric Modulator Program For The Treatment ...
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- Sosei Heptares reported its FY2021 financial result and provided an update on operational activities
February 2022 Read more at the source #DrGPCR #GPCR #IndustryNews
- Sosei Heptares Enters Antibody Discovery Agreement with Twist Bioscience to Discover and Develop ...
Discovery Agreement with Twist Bioscience to Discover and Develop Novel Therapeutic Antibodies against GPCR world-leading StaR® (stabilized receptor) platform to generate novel antibody leads to disease-relevant GPCR Cambridge, UK, 16 December 2021 – Sosei Group Corporation (“the Company”; TSE: 4565), the world leader in GPCR-focused announced a strategic collaboration to discover therapeutic antibodies against G protein-coupled receptors (GPCR Read more at the source #DrGPCR #GPCR #IndustryNews
- Crinetics Pharmaceuticals Expands Executive Team With Appointment Of James Hassard As Chief ...
Read more at the source #DrGPCR #GPCR #IndustryNews