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understand how and where these compounds interact with the receptor, paving the way for structure-based drug design He received his Ph.D. in Pharmaceutics from the University of Minnesota in 2022, studying the pharmacokinetics

contributing as a professor, senior lecturer, editorial board member, and scientific officer in both pharmaceutical

. 🔒 Read Publication April 3, 2026 Lilly to acquire Centessa Pharmaceuticals to advance treatments for

Katarina Nemec " I am a pharmacist with an interest in systems pharmacology and precision medicine.

We help GPCR innovators design systems, strategies, and operating frameworks that drive predictable growth Our work helps biotech startups, research organizations, and CROs design operating systems that enable Core themes: Strategic Planning for Biotech Growth Operational System Design (OS) Cross-functional Team you’re leading a GPCR startup, a CRO, or an academic lab ready to scale, Timeline Strategy helps you design

Other academic interests of his include studying pharmaceutical finance & healthcare administration and

Centre at the University of Glasgow, a £130M collaborative initiative housing over 550 researchers designed His recent work on muscarinic acetylcholine receptor modulation and structure-guided design of M1 receptor

Designed for pharmacologists, drug discovery scientists, and translational researchers working on temporal editor at the NIH Assay Guidance Manual and regularly teaches advanced pharmacology and experimental design

We’re thrilled to unveil our ever-expanding course roster—designed to help you stay at the cutting edge A combined in silico approach to design peptide ligands with increased receptor-subtype selectivity Adam toward Arrestins Structural and Molecular Insights into GPCR Function A combined in silico approach to design pain , spinal cord dorsal horn , OPN3 , cAMP signalin g , MC4R , docking , opioid , peptide ligand design , protein design , Ca2+ oscillation , GPCRs , basal activity , purinergic receptor , substrate stiffness

Themes of the Conversation Silicon-based DNA synthesis and the end of degenerate oligos in library design Motif-directed library design — encoding ligand-binding sequences into CDR3 architecture The library Twist's silicon platform produces pools of discrete, designed sequences — a shift in how synthetic libraries The design decision is the library's main differentiator. A motif-directed library reaches targets its motifs weren't designed for.

She has advanced the use of computational methods to meet the challenges of designing therapeutics with molecular dynamics simulation methods with emphasis on application to G-protein coupled receptors and drug design

— Academic–industry collaborations in GPCR drug discovery Insights from collaborative research with pharmaceutical It also showed me how important GPCR research is in pharmaceutical development.

Now at the University of Glasgow, his primary research interests are focused on the rational design of at the University of Glasgow underpinned by a £118M new build that will house over 550 researchers designed

dismissal is partly methodological and partly personal: the proudest moment of her scientific life was designing Nordisk, and into biotech at InterAx — where the next challenge is using functional fingerprints to design InterAx treats GPCR pharmacology the way engineers treat aircraft design: build the mathematical model Her most formative scientific moment was designing a compound in HEK293 cells from a hypothesis at Novo numbers miss what a ligand is really doing 16:40 — AI plus "real intelligence": functional data in drug design

Every session is designed to move your science forward. They're designed for scientists who want deep, data-driven discussion rather than surface-level overviews These sessions are designed for interaction — scientists asking direct questions and getting real answers GPCR pharmacology, signaling, structural biology, allosteric modulation, biased agonism, assay design

responses 🔹 Cutting-edge methods for quantifying bias 📊 🔹 Strategies to harness bias for better drug design drug efficacy more precisely. 💊 Therapeutic Potential : Understanding bias enables researchers to design to navigate this crucial gap. 📌 The Future of Drug Development 🚀 🔹 By integrating bias into drug design Ready to explore the future of biased drug design? Let’s dive in!

The episode explores gpcr internalization , fluorescence-based probe design, and how functional assay academic tool development to real-world adoption Balancing innovation with validation in GPCR assay design By combining fluorophore design, ligand chemistry, and pharmacology, his work enables precise visualization

circuits — insights that inform next-generation functional assay development and translational therapeutic design changed our understanding of GPCR signaling in metabolic tissues What collaborative chemistry enabled in designing

We designed the Ecosystem to support your work —no matter where you are in your GPCR journey. contributing behind-the-scenes tools and insight What Makes the Ecosystem Different Built for Drug Discovery Designed by scientists in the GPCR space to accelerate your research goals Collaborative by Design Connects researchers

lie at the interface of structural biology and drug discovery, where molecular structures inform the design I can imagine myself in a biotech or pharmaceutical environment where I’m helping guide drug development

Bryan Roth on the DARPA-funded effort to design a non-psychedelic psychedelic for depression — and why effort his lab is leading to answer that question through structure-guided drug discovery, biased ligand design are biological, not chemical Polypharmacology for complex neuropsychiatric disease Functional assay design Roth argues, belongs to designed polypharmacology.

provide a molecular explanation of small molecules for their pre-clinical efficacy and to support the design

for twelve years, through the company's acquisition by Sosei, helping establish structure-based drug design Scientific Themes of the Conversation Structure-based GPCR drug design and the thermostabilization breakthrough membrane protein team from scratch 15:29 Unexpected allosteric pockets and the next wave of GPCR drug design her team made considerable breakthroughs in the field of GPCR stabilization and structure-based drug design

GPCR — an ecosystem of podcasts, newsletters, summits, and working spaces designed to give the field Generate Biomedicines, where she worked on class B peptide receptor engineering using AI-driven protein design Scientific community as infrastructure — what connective tissue a 400-receptor field actually needs Assay design Building during a pandemic is a design constraint, not a footnote. Dr.

He explains what chemical design can solve that antibodies can’t, how to validate functional assay systems Why this matters How a chemist with zero biology training became a leader in GPCR probe design.

Discover our comprehensive Trademark Policy designed to protect the integrity and uniqueness of Dr. Buttons And Badges Guideline These guidelines provide you with the design specification for various Dr GPCR Logo in different marketing materials, such as a new T-shirt design, a toy, software packaging, These trademarks include the Logo, Buttons, Badges, Website Design, and other pictures and graphic designs

With a deep focus on structure-based drug design, Jens discusses how his lab bridges simulation and experiment—and Outside academia, he advises companies through a consulting arm focused on ligand design strategy.

understand the mechanism and structural bases for ligand binding and efficacy to help optimize the design The Sunahara lab has also been developing protein-based therapeutics using structure-guided design and

Designed for structural pharmacologists, cell biologists, and drug discovery scientists working on GPCR

I have extensive training in computer-aided drug design.