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Results found for "Jose Maldonado"
- Odorant receptors – a bit of smell for drug discovery
ORs are highly expressed by olfactory sensory neurons of the nose where they are activated by different epithelial cells proliferation via activation by β-ionone which initiates prostate cancer cell cycle arrest (Jones
- Unlocking the Therapeutic Potential of Previously Undruggable GPCRs
Twice-daily treatment with mOB-004 dose-dependently suppressed monocyte infiltration into the peritoneum cavity, achieving complete blockade at the highest dose level.
- Artificial intelligence – faster, smarter, cheaper GPCR drug discovery
GPCR-related knowledge, AI can help identify patient-specific GPCR targets and optimize drug selection and dosing
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