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<< Back to podcast list Strategic Partner(s) Martin Audet About Dr. the Institute of Pharmacology of Sherbrooke and is an emerging leader in the structural biology of G Research in San Diego and the University of Southern California in Los Angeles as a member of Raymond Stevens

<< Back to podcast list Strategic Partner(s) Nicole Perry-Hauser About Nicole (Nicki) Perry-Hauser I research fellow endeavoring to build a productive, independent scientific research career in adhesion G

<< Back to podcast list Strategic Partner(s) Dr. Jean-Philippe Pin About Dr. Since then, he has been studying the allosteric modulation and activation mechanism of this family of G

<< Back to podcast list Strategic Partner(s) Empowering Drug Discovery for the GPCR Community with Dr developing and innovating technologies to solve broad questions in pharmacology, with a specific focus on G-protein

<< Back to podcast list Strategic Partner(s) Dr. Lukas Grätz About Dr. multiple areas of GPCR research such as sequence alignments, generic numbering systems, structure data, G

<< Back to podcast list Strategic Partner(s) Dr. Yamina Berchiche About Dr. Yamina Berchiche Dr. GPCR, an ecosystem designed to bring together stakeholders interested in using G-Protein Coupled Receptors

<< Back to podcast list Strategic Partner(s) Dr. Sudha Shenoy About Dr. Sudha Shenoy Dr. Shenoy’s postdoctoral research discovered that ubiquitination of mammalian G protein-coupled receptors

<< Back to podcast list Strategic Partner(s) GPCR location matters with Dr. In my PhD, I studied the nanoscale spatial organization of G protein-coupled receptors (GPCRs) at the

<< Back to podcast list Strategic Partner(s) Brendan Wilkins About Brendan Wilkins "Brendan completed research assistant at the Victor Chang Cardiac Research Institute where he investigated the orphan G

<< Back to podcast list Strategic Partner(s) Gáspár Pándy-Szekeres About Gáspár Pándy-Szekeres " After multiple areas of GPCR research such as sequence alignments, generic numbering systems, structure data, G

<< Back to podcast list Strategic Partner(s) Dr. Kenneth A. Jacobson About Dr. Kenneth A. He adapts interdisciplinary approaches (synthesis, modeling, pharmacology) to study G protein-coupled

<< Back to podcast list Strategic Partner(s) The Role of Quantitative Sciences in GPCRs with Dr. contributions in developing constrained molecular dynamics simulation methods with emphasis on application to G-protein

<< Back to podcast list Strategic Partner(s) Dr. Graeme Milligan About Dr. His main research group centers on the function, structure, and regulation of G protein-coupled receptors

<< Back to podcast list Strategic Partner(s) Dr. Nicholas Holliday About Dr. University of Nottingham in 2006, where he is now Associate Professor, establishing a lab focused on G

<< Back to podcast list Strategic Partner(s) Developing new tools to uncover GPCR signaling patterns the lab works on diverse models and diseases, and has developed a wide array of tools to dissect GPCR/G

<< Back to podcast list Strategic Partner(s) Dr. Aylin Hanyaloglu About Dr. Aylin Hanyaloglu Dr. Francisco with Professor Mark von Zastrow where she identified novel core cellular machinery critical for G

<< Back to podcast list Strategic Partner(s) Dr. Sai Prasad Pydi About Dr. Sai Prasad Pydi Dr. Prasad Pydi obtained his Ph.D. from the University of Manitoba – Canada, where he was introduced to G

<< Back to podcast list Strategic Partner(s) Dr. Françoise Bachelerie About Dr. reviewed the standard nomenclature for chemokine receptors that are categorized into a large subgroup of G

<< Back to podcast list Strategic Partner(s) Dr. Adriano Marchese About Dr. Philadelphia, PA, for his postdoctoral training in Jeff Benovic’s laboratory studying the regulation of G

<< Back to podcast list Strategic Partner(s) Dr. Ralf Jockers About Dr. He is the Research director at INSERM with a specific interest in G protein-coupled receptors by developing

. << Back to podcast list Strategic Partner(s) Anita Nivedha: Computational Dynamics of Ligand Bias in GPCR Signaling Scientific Abstract G protein–coupled receptors (GPCRs) transmit extracellular signals Communication routes toward G proteins differed from those toward arrestins. The result is activation of intracellular signaling partners like G proteins or β-arrestins. Then we compared pathways leading to G proteins versus β-arrestins.

. << Back to podcast list Strategic Partner(s) Robert J. His lab developed the GRK (G protein-coupled receptor kinase) family and discovered the beta-arrestins , proteins now understood as central mediators of receptor desensitization and G protein-independent Lefkowitz was awarded the Nobel Prize in Chemistry, shared with Brian Kobilka, for studies of G protein-coupled Functional analogies between the two systems had been recognized — both were G protein-coupled — but

<< Back to podcast list Strategic Partner(s) Dr. Timo De Groof About Dr. Timo De Groof Dr. nanobody platform within the research group and used this platform to develop nanobodies targeting viral G

<< Back to podcast list Strategic Partner(s) Dr. Kathleen Caron About Kathleen M. Caron Kathleen M. With a special emphasis on G protein coupled receptors and receptor activity modifying proteins in vascular

<< Back to podcast list Strategic Partner(s) Dr. Davide Calebiro About Dr. biologists, chemists, physicists, engineers and computer scientists focusing on the basic mechanisms of G

<< Back to podcast list Strategic Partner(s) Dr. Sudarshan Rajagopal About Dr. identifying novel signal transduction mechanisms of GPCRs, such as the formation of complexes between G

<< Back to podcast list Strategic Partner(s) Inês Pinheiro, Monserrat Avila Zozaya & Yamina Berchiche GPCR, an ecosystem designed to bring together stakeholders interested in using G-Protein Coupled Receptors

. << Back to podcast list Strategic Partner(s) Arun Shukla: How Two Arrestins Regulate 800 GPCRs The so-called non-canonical GPCRs — receptors once dismissed as non-functional because they don't couple to G Receptors like CXCR7, C5L2, and TQIP6 were long dismissed as non-canonical because they don't couple to G Biased agonism is harder than the opioid story suggested The neat bifurcation between G-protein and beta-arrestin

. << Back to podcast list Strategic Partner(s) Chris Tate: Thermostabilizing GPCRs for Structural Biology interface sits on helix 1, involves a domain-swapped N-terminus and helix 7, is twice the area of the G In 2016 mini-G proteins were developed as a tool for the structure determination of GPCRs in the fully coupled to either mini-Gs or mini-Go, and also by electron cryo-microscopy of receptors coupled to mini G

<< Back to podcast list Strategic Partner(s) Dr. Michael Feigin About Dr. Michael Feigin "Dr. Craig Malbon at SUNY Stony Brook studying the role of G-protein coupled receptors (GPCRs) and their regulators They also discussed his research on cell polarity and its role in cancer progression, his work on G-protein He also discussed his work on G-protein coupled receptors (GPCRs) in breast cancer, identifying GPR161