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<< Back to podcast list Strategic Partner(s) Dr. Bianca Plouffe About Dr. Bianca Plouffe Dr. Robert Lefkowitz , which led to the finding that both β-arrestin and G protein can simultaneously bind Funded by a Wellcome Trust Seed Award, she investigated biased and compartmentalized G protein signaling

function Structural Determinants Of GAIN Domain Autoproteolysis And Cleavage Resistance Of Adhesion G Seufert Structural Determinants Of GAIN Domain Autoproteolysis And Cleavage Resistance Of Adhesion G module of fourteen domains which regulates signaling Sumit Bandekar Abstract "Cadherin EGF Laminin G seven-pass G-type receptors (CELSRs) are conserved adhesion G protein-coupled receptors; they are essential protein regions, whose dynamics mediate solvent-accessibility of the catalytically active GPS triad HL|S/

Its Relevance For Adhesion GPCR Signaling In Vivo Lara-Sophie Brodmerkel Novel isoforms of adhesion G Louis, 660 S. Euclid Ave, St. Louis, MO 63108, USA. Park B, Mohamed M, Li H, Elkholy A, Torrelli-Diljohn A, Kim JH, Jeong K, Murphy JM, Harvey CA, Dunlap S, For Adhesion GPCR Signaling In Vivo Lara-Sophie Brodmerkel Abstract "Over the last years, Adhesion G The current methods for testing KCC-07’s ability to reactivate ADGRB1 expression involve western blotting

<< Back to podcast list Strategic Partner(s) Empowering Drug Discovery for the GPCR Community with Dr developing and innovating technologies to solve broad questions in pharmacology, with a specific focus on G-protein

<< Back to podcast list Strategic Partner(s) Dr. Jean-Philippe Pin About Dr. Since then, he has been studying the allosteric modulation and activation mechanism of this family of G

<< Back to podcast list Strategic Partner(s) Nicole Perry-Hauser About Nicole (Nicki) Perry-Hauser I research fellow endeavoring to build a productive, independent scientific research career in adhesion G

<< Back to podcast list Strategic Partner(s) Dr. J. In this episode, Silvio discusses G protein signaling in the context of cancer, immunotherapies, and

Terry Kenakin ’s hands-on workshop, The Practical Assessment of Signaling Bias . Didn’t sign up? and Webinars March 19, 2025 | Advancing obesity drug discovery: Cell-based assays for GLP-1 and the G-Suite SLAS Europe 2025 NEW May 20 - 22, 2025 |4th GPCRs-Targeted Drug Discovery Summit June 22 - 26, 2025 | G IMFRE gels , Regenerative healing , Skin repair , Wound healing , A2B adenosine receptor , Calcium , G maresin 1 , microglia , nerve injury , neuropathic pain , spinal cord dorsal horn , OPN3 , cAMP signalin g

<< Back to podcast list Strategic Partner(s) Dr. Simone Prömel & Dr. Ines Liebscher About Dr. on the different modes of action of Adhesion GPCRs and found that they do not only mediate classical G Starting with proving and characterizing G-protein coupling, Ines spends several years studying the activation

<< Back to podcast list Strategic Partner(s) Dr. Canada where she obtained her Ph.D. at the University of Western Ontario, working on the regulation of G

<< Back to podcast list Strategic Partner(s) GPCR location matters with Dr. In my PhD, I studied the nanoscale spatial organization of G protein-coupled receptors (GPCRs) at the

<< Back to podcast list Strategic Partner(s) The Scientist's Compass: From Academia to Entrepreneurship University of Nottingham, where he provides leadership in structural and biophysical pharmacology of G Scherrer Institute and ETH Zürich in Switzerland, changing his attention to structural pharmacology of G

<< Back to podcast list Strategic Partner(s) Irfan Dhanidina, Dr. Kathleen Caron and Dr. With a special emphasis on G protein coupled receptors and receptor activity modifying proteins in vascular Slosky’s research is focused on understanding how neuropeptide G protein-coupled receptors (GPCRs) regulate Marc G. Caron at Duke University. Dr. These ligands stimulate receptor β-arrestin recruitment without activating canonical G protein signaling

<< Back to podcast list Strategic Partner(s) Dr. Sudha Shenoy About Dr. Sudha Shenoy Dr. Shenoy’s postdoctoral research discovered that ubiquitination of mammalian G protein-coupled receptors

<< Back to podcast list Strategic Partner(s) Dr. Yamina Berchiche About Dr. Yamina Berchiche Dr. GPCR, an ecosystem designed to bring together stakeholders interested in using G-Protein Coupled Receptors

<< Back to podcast list Strategic Partner(s) Dr. Paul Insel About this episode In 1975, Dr. Alfred Gillman , co-recipient of the 1994 Nobel Prize in Physiology or Medicine for their discovery of G-proteins

<< Back to podcast list Strategic Partner(s) Brendan Wilkins About Brendan Wilkins "Brendan completed research assistant at the Victor Chang Cardiac Research Institute where he investigated the orphan G

<< Back to podcast list Strategic Partner(s) Dr. Lukas Grätz About Dr. multiple areas of GPCR research such as sequence alignments, generic numbering systems, structure data, G

<< Back to podcast list Strategic Partner(s) Gáspár Pándy-Szekeres About Gáspár Pándy-Szekeres " After multiple areas of GPCR research such as sequence alignments, generic numbering systems, structure data, G

Lab LinkedIn Characterization of Phenotypes Associated with GPR110 Deletion Hee-Yong Kim Abstract "G-protein Synaptamide, an endogenous ligand for GPR110, binds to the N-terminal G-protein autoproteolysis-inducing Additionally, the bacterium Vibrio fischeri also induces mating in S. rosetta cultures, suggesting that adhesion GPCR, named Cupidon, that regulates the switch from vegetative growth to sexual reproduction in S. Together, our results suggest that Cupidon prevents sexual reproduction in S. rosetta under high nutrient

<< Back to podcast list Strategic Partner(s) Dr. Nicholas Holliday About Dr. University of Nottingham in 2006, where he is now Associate Professor, establishing a lab focused on G

<< Back to podcast list Strategic Partner(s) Dr. Kenneth A. Jacobson About Dr. Kenneth A. He adapts interdisciplinary approaches (synthesis, modeling, pharmacology) to study G protein-coupled

<< Back to podcast list Strategic Partner(s) Dr. Graeme Milligan About Dr. His main research group centers on the function, structure, and regulation of G protein-coupled receptors

<< Back to podcast list Strategic Partner(s) The Role of Quantitative Sciences in GPCRs with Dr. contributions in developing constrained molecular dynamics simulation methods with emphasis on application to G-protein

<< Back to podcast list Strategic Partner(s) Re-cap of Endocrine Metabolic GPCR 2024 with the Organizers Francisco with Professor Mark von Zastrow where she identified novel core cellular machinery critical for G continued to undertake postdoctoral research in Oxford, investigating the signalling and trafficking of the G

GPCR Title: Balancing G Protein Selectivity and Efficacy in the Adenosine A2A Receptor About Louis-Philippe My primary research focus lies in gaining deeper insights into the structural mechanisms governing G protein-coupled receptors (GPCRs) and G protein activation. GPCR Title: Development of a Transgenic Mouse Platform for the Detection of Endogenous G protein Activity Mikel Garcia-Marcos which investigates GPCR and G protein signaling" Remi Janicot on the web Boston University

He discusses biased signaling in GPCR research, developing biosensors for G protein activity, networking Highlights of the week Structural insights into prolactin-releasing peptide receptor signaling and G-protein and Webinars March 19, 2025 | Advancing obesity drug discovery: Cell-based assays for GLP-1 and the G-Suite 2025 - Germany May 20 - 22, 2025 |4th GPCRs-Targeted Drug Discovery Summit - USA June 22 - 26, 2025 | G and more Single-Molecule Insights into GPCR Conformational Landscapes Covalent functionalization of G

<< Back to podcast list Strategic Partner(s) Developing new tools to uncover GPCR signaling patterns the lab works on diverse models and diseases, and has developed a wide array of tools to dissect GPCR/G

<< Back to podcast list Strategic Partner(s) Dr. Sai Prasad Pydi About Dr. Sai Prasad Pydi Dr. Prasad Pydi obtained his Ph.D. from the University of Manitoba – Canada, where he was introduced to G

<< Back to podcast list Strategic Partner(s) Dr. Aylin Hanyaloglu About Dr. Aylin Hanyaloglu Dr. Francisco with Professor Mark von Zastrow where she identified novel core cellular machinery critical for G