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- Dr. G. Aditya Kumar | Dr. GPCR Ecosystem
Aditya Kumar About Dr. G. Aditya Kumar Dr. Aditya Kumar is a postdoctoral fellow at the University of Michigan Medical School. Aditya is interested in understanding the role of the membrane microenvironment in the subcellular organization In addition, he explored the role of the host membrane in the entry of intracellular pathogens into macrophages Aditya Kumar on the web University of Michigan Puthenveedu Lab Google Scholar NIH ORCID LinkedIn Twitter
- Session VI | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program Work from our lab showed that the PCP components, including ADGRC2 and ADGRC3, are localized in the developing We showed that ADGRC2 and ADGRC3 are required for the restoration of glutamatergic synapses in prefrontal as compared to control ADC targeting RSV glycoprotein F (19.964 nM). In vivo intratumoral administration of the ADC in patient-derived GBM xenografts in the brain of immunodeficient
- Leave for dinner reception | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program
- Session VIII | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program < Back to Full Agenda Session VIII Physiological and pathological roles of AGPCRs in the periphery ADGRG1 /GPR56 regulates survival of terminally differentiated CD8+ T cells Cheng-Chih Hsiao Adhesion GPCR GPR116 /Adgrf5 controls a lineage of anti-thermogenic adipocytes with implications for adaptive thermogenesis GPCR GPR116/Adgrf5 controls a lineage of anti-thermogenic adipocytes with implications for adaptive
- Dr. Adriano Marchese | Dr. GPCR Ecosystem
Adriano Marchese About Dr. Adriano Marchese Adriano Marchese is a Professor of Biochemistry at the Medical College of Wisconsin. Adriano received his Bachelor of Science degree in Pharmacology in 1991 from the University of Toronto In 2004 Adriano joined the faculty of the Department of Pharmacology at Loyola University Chicago. Adriano Marchese on the web Twitter LinkedIn Google Scholar Website Dr.
- 🚀 New Workshop: Practical Quantification of Allosteric Modulation Join Dr. Terry Kenakin on May 1st, 2025, for an advanced live workshop on allosteric modulators in GPCR drug discovery. Learn how to: ✔️ Identify, measure, and quantify allosteric properties ✔️ Apply functional allosteric models to determine mechanisms of action ✔️ Confirm allostery through kinetic analysis 📅 Date: May 1st, 2025 ⏳ Registration deadline: April 18th 📍 Live on Google Meet 🔗 Register now: https://www.ecosystem.drgpcr.com/event-details-registration/practical-quantification-of-allosteric-modulation #GPCR #Allostery #DrugDiscovery #Pharmacology | Dr. GPCR Ecosystem
Terry Kenakin on May 1st, 2025, for an advanced live workshop on allosteric modulators in GPCR drug discovery Terry Kenakin on May 1st, 2025 , for an advanced live workshop on allosteric modulators in GPCR drug
- New biosensor technologies are shedding light on GPCR dynamics directly in cells, offering exciting possibilities for multiplexing and miniaturization! Curious about how these advances could impact drug discovery? Check out the latest review on GPCR biosensors. Check out the latest GPCR news in the Ecosystem today! You’ll need to register but don’t worry, it’s Free! | Dr. GPCR Ecosystem
Curious about how these advances could impact drug discovery? Curious about how these advances could impact drug discovery?
- 🔥 New Course Alert! “Development of GPCR Ligands as Therapeutic Drugs” with Dr. Terry Kenakin is here! Spots are filling up fast—Premium Members get 25% off! This advanced course is exclusively available in the Ecosystem, so don’t miss your chance to learn from the best. 🔹 Secure your spot now! 👉 https://www.ecosystem.drgpcr.com/event-details-registration/development-of-gpcr-ligands-as-therapeutic-drugs #gpcr #drgpcr #pharmacolgy #drugdiscovery #research | Dr. GPCR Ecosystem
This advanced course is exclusively available in the Ecosystem, so don’t miss your chance to learn from This advanced course is exclusively available in the Ecosystem, so don’t miss your chance to learn from
- What’s one key piece of advice from Ian Chronis in Ep.164 of the Dr.GPCR Podcast?Listen to other scientists’ research—it’s a great way to stay motivated and inspired 🚀 Don’t miss this insightful conversation on GPCRs, pharmacology, and scientific discovery! ✅ https://buff.ly/FTB69y9 #GPCR #DrGPCR #SciencePodcast #Pharmacology #CancerResearch | Dr. GPCR Ecosystem
Home → Flash News → What’s one key piece of advice from Ian Chronis in Ep.164 of the Dr.GPCR Podcast? GPCR Podcast What’s one key piece of advice from Ian Chronis in Ep.164 of the Dr.GPCR Podcast?
- About Dr. GPCR Ecosystem | Uniting the GPCR Community to Advance Drug Discovery
GPCR Ecosystem We unite the GPCR community to advance drug discovery. Contact Us Our Mission Advance GPCR science and drug discovery by connecting people, data, and opportunities
- Session II | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program function Monserrat Avila Zozaya Adhesion GPCR BAI1/ADGRB1 can block IGF1R-mediated growth signalling, GPCR Adhesion GPCR BAI1/ADGRB1 can block IGF1R-mediated growth signalling, increase radiosensitivity GPCRs ADGRB1 and ADGRB3. overexpressing wild-type and N-glycosylation mutants of ADGRG6.
- Session IX / Technology capsule: Light on aGPCR signaling and function | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program
- Welcoming Remarks | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program
- Interaction with the cell adhesion molecule NEGR1 affects mGluR5 cell signalling
Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to schedule Interaction with the cell adhesion
- Advanced data analysis for GPCR pharmacology | Dr. GPCR Ecosystem
Advanced data analysis for GPCR pharmacology Dr.
- Did you know that cell types can affect the GPCR-mediated signalling cascade? Check out this paper to know how different cell types affect the A2BR-mediated calcium signalling system. Check out the latest GPCR news in the Ecosystem today! You’ll need to register but don’t worry, it’s Free! ➡️https://www.ecosystem.drgpcr.com/receptor-activation-and-signaling/a2b-adenosine-receptor-triggered-intracellular-calcium-mobilization%3A-cell-type-dependent-involvement-of-gi%2C-gq%2C-gs-proteins-and-protein-kinase-c #gpcr #drgpcr | Dr. GPCR Ecosystem
➡️https://www.ecosystem.drgpcr.com/receptor-activation-and-signaling/a2b-adenosine-receptor-triggered-intracellular-calcium-mobilization ➡️ https:// www.ecosystem.drgpcr.com/receptor-activation-and-signaling/a2b-adenosine-receptor-triggered-intracellular-calcium-mobilization
- Student Flash Presentations | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Brain angiogenesis inhibitor 3 (BAI3/ADGRB3), a member of the BAI1-3 subfamily of adhesion GPCRS, has Lara-Sophie Brodmerkel on the web University of Leipzig Novel isoforms of adhesion GPCR B1 (ADGRB1/BAI1 Currently, he is working to elucidate the role of ADGRB1 and ADGRB3 in medulloblastoma (pediatric brain , Adgre5, Adgrf1, Adgrf5, Adgrg1, and Adgrg3). Our lab has previously shown that expression of adhesion GPCR BAI1 (ADGRB1) is lost by epigenetic silencing
- State of the Art Talk | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program HERE < Back to Full Agenda State of the Art Talk Adhesion GPCR in Mechanobiology Abstract Only Available
- GPCRs regulate key biological processes, but how exactly do inhibitory Gαi proteins control signal transduction beyond adenylyl cyclase suppression? New research sheds light on these pathways! ✨ Want to learn more? Did you know that we work hard to bring you the most recent GPCR News, weekly? Catch up today in the Ecosystem using your free site membership! | Dr. GPCR Ecosystem
biological processes, but how exactly do inhibitory Gαi proteins control signal transduction beyond adenylyl biological processes, but how exactly do inhibitory Gαi proteins control signal transduction beyond adenylyl
- New cryo-EM insights reveal how extracellular domains communicate with transmembrane regions in holo-adhesion GPCRs, uncovering mechanisms behind receptor activation. Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️https://www.ecosystem.drgpcr.com/adhesion-gpcrs/conformational-coupling-between-extracellular-and-transmembrane-domains-modulates-holo-adhesion-gpcr-function #gpcr #drgpcr | Dr. GPCR Ecosystem
New cryo-EM insights reveal how extracellular domains communicate with transmembrane regions in holo-adhesion Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️https://www.ecosystem.drgpcr.com/adhesion-gpcrs /conformational-coupling-between-extracellular-and-transmembrane-domains-modulates-holo-adhesion-gpcr-function New cryo-EM insights reveal how extracellular domains communicate with transmembrane regions in holo-adhesion /conformational-coupling-between-extracellular-and-transmembrane-domains-modulates-holo-adhesion-gpcr-function
- The Dr. GPCR Podcast is back! After a long break, a new episode will be released today 🎧 Join us in 2025 with a year filled with GPCRs, as we share with specialists about their career paths, the latest breakthroughs, their advice, and inspiring stories. 📅 Ep. 157 drops today January 9th at 10 AM EST. Don’t miss it! ✅ Stay tuned & subscribe at https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-157-with-dr.-nagarajan-vaidehi | Dr. GPCR Ecosystem
with GPCRs, as we share with specialists about their career paths, the latest breakthroughs, their advice with GPCRs, as we share with specialists about their career paths, the latest breakthroughs, their advice
- Started in medicinal chemistry. Got hooked on ligand design. Dr. Maria Majellaro didn’t plan to run a biotech company. A thesis project, a mentor’s advice, and a leap during the pandemic changed everything. Now she’s leading Celtarys, building custom fluorescent probes, and partnering with Dr. GPCR to support assay development worldwide. Meet Celtarys and learn more about its leading work on ligand-linker-fluorophore chemistry 🚀 ✳️ Listen now: https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-168-with-dr.-maria-majellaro-from-celtarys #GPCRcommunity #DrGPCR #FluorescentLigands #GPCRdrugDiscovery #ScientificLeadership #BiotechInnovation | Dr. GPCR Ecosystem
A thesis project, a mentor’s advice, and a leap during the pandemic changed everything. A thesis project, a mentor’s advice, and a leap during the pandemic changed everything.
- In case you haven’t heard, Dr. Terry Kenakin will soon start the course Principles of Pharmacology II - Advanced Methods for the Optimization of Candidate Selection 📖 The five-lecture series describes essential additional elements to GPCR discovery programs that extend the discovery process and increase therapeutic opportunity. | Dr. GPCR Ecosystem
Terry Kenakin will soon start the course Principles of Pharmacology II - Advanced Methods for the Optimization of Candidate Selection 📖 The five-lecture series describes essential additional elements to GPCR discovery Terry Kenakin will soon start the course Principles of Pharmacology II - Advanced Methods for the Optimization of Candidate Selection 📖 The five-lecture series describes essential additional elements to GPCR discovery https://www.ecosystem.drgpcr.com/advanced-methods-for-the-optimization-of-candidate-selection #gpcr #
- Registration & Coffee with light breakfast | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program
- Ready to stand out in the GPCR world? Take advantage of a platform where you can network within your field! 🌍 Showcase your expertise by keeping your profile up-to-date on Dr. GPCR. | Dr. GPCR Ecosystem
Take advantage of a platform where you can network within your field! Take advantage of a platform where you can network within your field!
- ⚠️ Registration Deadline today! This is your last chance to register for Principles of Pharmacology II - Advanced Methods for the Optimization of Candidate Selection with Dr. Terry Kenakin. Learn more about new ligands and new GPCR behaviors that produce unique drug profiles. | Dr. GPCR Ecosystem
This is your last chance to register for Principles of Pharmacology II - Advanced Methods for the Optimization This is your last chance to register for Principles of Pharmacology II - Advanced Methods for the Optimization https://www.ecosystem.drgpcr.com/advanced-methods-for-the-optimization-of-candidate-selection #gpcr #
- Did you know that GPR180 helps regulate lipid metabolism and may play a role in preventing obesity? recent study shows that overexpression of GPR180 in adipose tissue improves lipid metabolism and protects against HFD-induced obesity, while its knockout worsens lipid accumulation. This finding highlights GPR180 as a potential therapeutic target for metabolic disorders! Catch up on this exciting research in the Ecosystem today! 🏆📖 You’ll need to register, but don’t worry—it’s free! ➡️https://www.ecosystem.drgpcr.com/gpcrs-in-cardiology-endocrinology-and-taste/gpr180-reduces-adiposity-by-inhibiting-lipogenesis-and-fatty-acid-uptake-in-adipocytes #gpcr #drgpcr #metabolism #obesity | Dr. GPCR Ecosystem
recent study shows that overexpression of GPR180 in adipose tissue improves lipid metabolism and protects ➡️https://www.ecosystem.drgpcr.com/gpcrs-in-cardiology-endocrinology-and-taste/gpr180-reduces-adiposity-by-inhibiting-lipogenesis-and-fatty-acid-uptake-in-adipocytes recent study shows that overexpression of GPR180 in adipose tissue improves lipid metabolism and protects ➡️ https:// www.ecosystem.drgpcr.com/gpcrs-in-cardiology-endocrinology-and-taste/gpr180-reduces-adiposity-by-inhibiting-lipogenesis-and-fatty-acid-uptake-in-adipocytes
- Session III | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program G Protein-coupled receptors (aGPCRs or ADGRs). It was then adapted for the human aGPCRs CD97/ADGRE5 and Latrophilin/ADGRL3 and tested in HEK293T cells In addition, the platform was used to develop assays for high-throughput screening for challenging adhesion to preclinical candidate nomination and to provide the tools to advance adhesion GPCR biology."
- Posters | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program HERE < Back to Full Agenda Posters Interrogating The Role Of CELSR1 (ADGRC1) In Breast Cancer Caroline Kordon Deorphanization Of The Adhesion GPCRs GPR110 and GPR116 Tingzhen Shen Self-Cleavage of GPR110 Kordon Abstract "Adhesion G Protein-Coupled Receptors (aGPCRs) are key cell-adhesion molecules involved Júlia Rosell on the web LinkedIn Endocytic Cues Determine the Signaling Profile of Adhesion GPCR ADGRL1
- Coffee Break with pastries announcement of the aGEM award | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program





