She trained in protein biochemistry and neuroscience, completing her PhD in Germany and her postdoctoral Remulate connects fly neuroscience to human vascular and neurological pathology In the peripheral nervous Eurofins DiscoverX 00:29 - Introduction of Beatriz Blanco-Redondo; icebreaker 01:15 - Career path: from Spain

She moved to the University of Ottawa to complete a Ph.D. in Neuroscience.

passion, I recently started a postdoctoral fellowship to study the role of GPCRs in the mechanisms of pain

If the right ligand could engage G-protein signaling while sparing β-arrestin, pain relief might finally data can still predict FDA pharmacovigilance outcomes, and where iPSC-derived somatic systems actually pay characterization of the pharmacological properties of cannabinoids in conjunction with terpenes for pain

The therapeutic logic is that decoupling from the orthosteric site might preserve pain relief while altering We enhance your endogenous tone, we cause pain relief, maybe we mitigate some of these side effects."

Each of the three RAMPs can pair with a given receptor to produce a distinct complex - different ligand The scientists who persist, in her framing, are not the ones who feel less pain from those setbacks, She has gained experience from working in academia and at GSK as an industrial trainee.

Recognized with the Beckman Young Investigator Award, the Klingenstein-Simons Fellowship in Neuroscience

But loss has a way of sharpening focus—friends lost to overdose brought the opioid epidemic into painful

of opioid receptors and is currently focusing on the pharmacology of cannabinoids in the context of pain

encompassing neurological and psychiatric disorders, cardiovascular disease, obesity, diabetes, chronic pain

medicinal chemistry to bitter taste receptors 05:44 Trace amine-associated receptors on the edge of neuroscience

Breadth across physiology systems carries a professional cost that nobody warns you about Moving between neuroscience

encompassing neurological and psychiatric disorders, cardiovascular disease, obesity, diabetes, chronic pain

encompassing neurological and psychiatric disorders, cardiovascular disease, obesity, diabetes, chronic pain

Vanderbilt University before continuing her training as a postdoctoral fellow at the Vanderbilt Center for Neuroscience

components, allosteric modulation, and open questions 14:57 - Disease territory: epilepsy, spasticity, pain

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Mike's lab has two main areas of interest: 1) alternative polyadenylation as a targetable driver of pancreatic He shared that his interest in science originated from a young age and his desire to gain more knowledge However, he decided to undertake another postdoc to gain more experience and confidence. The conversation ended with Yamina expressing interest in learning more about Mike's two main research

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His main research group centers on the function, structure, and regulation of G protein-coupled receptors

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The main target of Dr.

GPCR About Ben Holland "Ben gained his masters in Engineering Science from Oxford, taking a specialisation

Clear Platform Assessment: Gain rapid, independent insight into GPCR platform risks and true therapeutic We made confident progress on a pivotal program and gained clarity on our next strategic focus.

During his last year of studies, Timo performed research in the biopharmaceutical company Argen X and gained

coupled receptors and receptor activity modifying proteins in vascular biology, the Caron laboratory has gained

The main focus of his lab’s research is on the mechanisms underlying biased agonism at chemokine receptors

At McGill, his laboratory has two main axes of research: 1) Studying interindividual vulnerability to

For this, we have worked in three main areas: the regulation of G protein-coupled receptor signaling