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GPCR Ecosystem. List your services and your brand on the world's first GPCR CRO Bank. The GPCR CRO Bank is a marketing-first offering designed to help service providers and tool companies GPCR is the world's largest nonprofit community focused on GPCRs. As a CRO partner, you'll gain trusted access to an engaged audience of biotech teams and drug discovery GPCR?

Weekly News, featuring expert insights on target engagement, a practical framework for irreversible drugs GPCR Weekly News - Oct 23 - The Power and Peril of Irreversible Drugs Published on October 23, 2025 Category Premium sneak peek inside. 🔹 Terry’s Corner: A practical framework for irreversible drugs—defining “ Jens Carlsson on predictive modeling—where structure-based design and MD guide experiments (and where #DrGPCR #GPCR Previous Next Recent Articles

as a potential drug target due to its high expression in triple negative breast cancer. GPCR Targeted Drugs and Gene Regulation in Cancer Cells Mike presented research on the effect of GPCR-targeted GPCRs and Cancer Immune Modulation Yamina and Mike had a discussion about their research on GPCRs, specifically Mike expressed a need for better tools to study GPCR localization in tissues. GPCR Podcast? Leave a Review.

Gabriele Kockelkoren shares: 🔬 How GPCR spatial organization shapes signaling and drug responses 🌍 the unknown is key to scientific breakthroughs A must-listen for biophysicists, pharmacologists, and drug GPCR Podcast 🎧 "You will always feel like you know nothing— and that’s completely fine." Gabriele Kockelkoren shares:🔬 How GPCR spatial organization shapes signaling and drug responses🌍 His the unknown is key to scientific breakthroughs A must-listen for biophysicists, pharmacologists, and drug

He currently leads a team that provides a mechanistic understanding of small molecule drug candidates Brian has contributed to the discovery or development of 5 marketed drugs through his work spanning molecular , biochemical, cellular, and in vivo assessment of drug candidates in many different physiological systems He continues to pioneer in drug discovery studying GPCRs and other target classes. GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review.

He currently leads a team that provides a mechanistic understanding of small molecule drug candidates Brian has contributed to the discovery or development of 5 marketed drugs through his work spanning molecular , biochemical, cellular, and in vivo assessment of drug candidates in many different physiological systems He continues to pioneer in drug discovery studying GPCRs and other target classes. GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review.

with numerous pharma and biotechs in understanding and applying in vitro pharmacology data to advance drug He specializes in kinetic analysis of drug action and is known for applying binding kinetics to the development He guided the in vitro biology efforts of the company for numerous drug discovery campaigns. of GPCR function to better target receptors. GPCR Member ResearchGate Dr. GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review.

During his Ph.D. with David Gloriam at the Department of Drug Design and Pharmacology in Copenhagen, of Molecular Biology in Cambridge, UK, where he was working on the impact of genetic variations on drug Award” for his work on GPCRs. Dr. Alexander S. GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks

signaling and drug discovery. Home → Flash News → How GPCR Spatial Signaling Sparked a Scientific Journey How GPCR Spatial Signaling spatial signaling — a field reshaping how we understand receptor biology and drug discovery. 🔓 Want deeper GPCR insights? uncomfortable truth: 👉 Your biotech is already running on an operating cadence you didn’t consciously design

His journey highlights the transition from general drug development to a deep dive into G protein-coupled Allosteric Modulation: The New Frontier of GPCR Drug Discovery Ben reflects on the emerging potential “The goal is to smash all the amazing biology together and make a drug.” design . 8. GPCR ecosystem , GPCR online course , GPCR scientist network , GPCR drug discovery , GPCR training program

into the structure, dynamics, and function of important classes of membrane proteins and prominent drug targets, including G protein-coupled receptors (GPCRs), transporters, channels, and 3 integrins. To this end, her lab uses several computational structural biology tools and rational drug design approaches GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks

schedule Illuminating Functional Selectivity and Allosterism at GPCRs. receptors involved in many, if not all, physiological responses, with the ultimate goal of improving drug in-cellulo measurement of protein-protein interactions, receptor trafficking and signalling, useful for drug GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires 22nd GPCR Retreat Sponsored by

Discover how strategic collaboration drives real GPCR drug discovery impact. GPCR Podcast If your model can’t change an experiment, what’s the point? That’s the standard Dr. The kind of impact that shows up in how experiments are designed, which compounds get prioritized, and In GPCR drug discovery, where complexity is the rule and timelines are tight, this kind of cross-functional GPCR Podcast: model predict discover #DrGPCR #GPCR #CollaborationInScience #ComputationalChemistry #Pharmacology

If you work with GPCRs, this perspective changes how you design experiments and interpret data. 🎧 Watch It shaped how we design experiments, make decisions, and lead teams. In this week’s Dr. #EarlyDiscovery #PharmaR&D #BiotechInnovation Irreversible kinetics = strategic lever in drug design Binding kinetics are a design variable, as critical as potency or clearance. Start designing them to happen.

engaged in researching molecular mechanisms that govern human (patho-)physiology and their interplay with drugs I aim to discover new therapeutic approaches, and druggable molecules or refine canonical drug targets to create drugs with fewer adverse effects. PhD studies in Martin Lohse lab at the Max Delbrueck Center in Berlin, I consolidated my knowledge of GPCRs GPCR Enjoying the Dr. GPCR Podcast? Leave a Review.

Juan José Fung is a Principal Scientist at GPCR Therapeutics, Inc , a drug discovery company focused Brian Kobilka , studying the dimerization of GPCRs. Dr. spent significant time in the industry studying membrane proteins, antibodies, and HTS methods for drug Juan José Fung on the web LinkedIn GPCR Therapeutics Dr. GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review.

Now at the University of Glasgow, his primary research interests are focused on the rational design of novel drugs to treat the three global health challenges of dementia, asthma, and malaria. staff supported by basic research grants investigating aspects of disease biology and the action of drugs at the University of Glasgow underpinned by a £118M new build that will house over 550 researchers designed GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review.

Michelle describes how reading those early papers on lipid-rich domains and GPCR–G protein compartmentalization The way signals are organized defines specificity, drug response, and potential for targeted therapies If you work with GPCRs, this perspective changes how you design experiments and interpret data. 🎧 Watch /leadership-luck-and-gpcr-signaling ✨ Join Premium: https://www.ecosystem.drgpcr.com/gpcr-university-pricing #GPCR #DrGPCR Previous Next Recent Articles

<< Back to podcast list Strategic Partner(s) The Role of Quantitative Sciences in GPCRs with Dr. She has advanced the use of computational methods to meet the challenges of designing therapeutics with molecular dynamics simulation methods with emphasis on application to G-protein coupled receptors and drug design." GPCR Enjoying the Dr. GPCR Podcast? Leave a Review.

Accelerated Program Progression: Design robust assay cascades and establish key go/no-go points to speed Accelerated Preclinical Progression I streamline critical operational processes, from advanced assay design drug discovery. Berchiche, and I understand the intricate challenges of GPCR drug discovery. drug discovery.

These receptors belong to the super-family of G-protein coupled receptors (GPCR), the major molecular target for drug development. and drug development technology. GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review. Imaging in Native Tissue How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology Thanks

signaling opens new doors in drug discovery. the Guest Michelle Halls is an Associate Professor at Monash University and Deputy Theme Leader of Drug How GPCR Collaboration Built an Innovation Engine ⸻ 🎓 Want more like this? GPCR Premium . GPCR Podcast? Leave a Review.

From her early doubts to designing preclinical models of fentanyl and xylazine overdose, she reflects podcast list Strategic Partner(s) Xylazine, Fentanyl, and the Fight for Breath with Catherine Demery Two drugs pharmacologist—led her to investigate how these drugs shut down breathing in different ways. Who Should Listen This episode is especially relevant for: GPCR drug discovery scientists Respiratory GPCR ecosystem , GPCR training program , GPCR podcast , opioid pharmacology , xylazine research , mu

Ray Stevens in 2013 solving several GPCR crystal structures, including that of the first serotonin receptor and in vitro drug discovery. Icahn School of Medicine at Mount Sinai in NYC, where I have been working on structure-function and drug discovery of GPCRs and transporters. GPCR Ecosystem Enjoying the Dr. GPCR Podcast? Leave a Review.

drug discovery . circuits — insights that inform next-generation functional assay development and translational therapeutic design Why this matters How receptor distribution in islets and brain circuits shapes incretin hormone drug collaborative chemistry enabled in designing receptor-targeted fluorescent ligands The moment when structural GPCR Podcast? Leave a Review.

Home → Flash News → master gpcr pharmacologic models before its too late Published on July 11, 2025 Category GPCR Weekly News Most GPCR teams aren’t failing because of bad science. This week’s GPCR Weekly News helps you fix that. Yamina’s Corner exposes the silent drift killing GPCR programs (and how to reverse it). ✳️ Read the Weekly News → https://www.ecosystem.drgpcr.com/post/crush-data-confusion-conquer-gpcr-drug-discovery

targets — a top-down rethink for drug discovery. << Back to podcast list Strategic Partner(s) GPCRs “We’re using outdated drugs. There are more elegant GPCR targets waiting to be explored.” He’s fascinated by transgenerational epigenetics — how parental pain, diet, or drug exposure can leave GPCR ecosystem, GPCR drug discovery, GPCR podcast, GPCR data platform, GPCR training program, RGS4, chronic GPCR Podcast? Leave a Review.

“I think I don’t have a linear trajectory… the beauty of seeing molecule design and reactions—thinking Alessandro Nicoli He studied pharmaceutical chemistry in Padua, where his fascination with molecular design close to experimental structures, provided a powerful starting point for docking, dynamics, and ligand design—especially drug discovery pipelines. GPCR ecosystem , GPCR online course , GPCR scientist network , GPCR drug discovery , GPCR training program

Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program signaling pathway of the ADGRA homolog Remoulade in Drosophila Beatriz Blanco Redondo The Adhesion GPCR The mammalian Remo homolog ADGRA2/Gpr124 cooperates with other GPCRs of the Frizzled family, and the Langenhan where I am studying and characterizing newly generated adhesion GPCR receptors in Drosophila Anaesthesiology and Intensive Care, Medical Faculty, Leipzig University, Leipzig, Germany 5 Institute for Drug

Dr GPCR is a 501(c)(3) non-profit. global GPCR community better — by upgrading the Dr GPCR University, creating more learning opportunities to make cutting-edge GPCR knowledge accessible to everyone Dr GPCR Retreat: offering free or affordable Together, we can accelerate GPCR discoveries and develop more effective drugs for everyone. 👉 Donate Now to Support the Dr GPCR Ecosystem