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detecting GPCR mRNAs in human immune cells and platelets, revealing significant findings that enhance our Therefore this study significantly advances our understanding of GPCR expression in human immune cells

Our results show that the short-term diffusion coefficient of the receptor decreases upon cholesterol These results are supported by our recent work and present observations that show polymerization of G-actin Taken together, our results bring out the interdependence of cholesterol and actin cytoskeleton in regulating

February 2022 "We are proud to announce the success of our IPO! Thank you to our shareholders, both historical and new, for their trust. The €25 million fundraising gives us the means to achieve our ambitions: to become a leading player in

However, our predictions were many folds shorter than those determined experimentally. Our results build a strong foundation for further improvement of our approach by rationalizing the kinetics

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screen and identified 361 genes that modify macrophage susceptibility to Hc infection, greatly expanding our also showed that the EMC promotes surface expression of C3aR, likely explaining its identification in our Taken together, our results provide new insight into host processes that affect Hc-macrophage interactions

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Take a few minutes, and dive into our GPCR coverage! We welcome GPCR paper suggestions! Let Mark Schmeizl, our Chief Matchmaker help. Contact him by filling out this form. Our November Dr. GPCR Newsletter is now available. This month's video newsletter features Dr. Alix Rouault as our special guest. Subscribe now!

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Our previous Markov State Model (MSM) analysis of molecular dynamics simulations of membrane-embedded Our analyses reveal that cholesterol inhibits phospholipid scrambling by occupying the TM6/7 interface

This week's highlights: Kudos to our partner, GPCR Therapeutics, for partnering with Bridge Biotherapeutics GPCR Ecosystem contents and perks, including our forums, private groups, and all Ecosystem members Go We'll pause our regular updates during this time and will resume our newsletter in the upcoming year

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Take advantage of our GPCR highlights of the week. Dr. fluorescent analogues for real-time binding studies of orphan GPCR GPR3: Save the dates: November 17: Join our You don't want to miss out on our monthly Dr. GPCR Newsletter for exclusive content, check out our latest video featuring Dr. Kathleen Caron.

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Altogether, our results highlight the previously unrecognized nuclear localization pattern of H2R. In this aspect, our present data shed new light on the unexplored H2R signaling mechanisms.

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Our results indicate that lateral diffusion parameters of serotonin1A receptors in normal cells are consistent Notably, our results show that statin-induced dynamic confinement could be reversed by destabilization

Our results show that a mutation in the K101 residue leads to loss in thermal stability of the serotonin1A We envision that our results could have potential implications in structural biological advancements

increased basal TrkB phosphorylation in the frontal cortex and hippocampus, which is in accordance with our Our data reveal the functional role of 5-HT2A–TrkB receptor heterodimerization and suggest that the regulated

August 2022 "We are happy to announce you our 2nd IRN i-GPCRnet meeting that will be held at the University

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Save the date: TOMORROW - November 17: Don't miss out on our final Dr. Kathleen Caron, as our video guest, subscribe now! microenvironment and the process of EBV-induced lymphomagenesis Tanso Biosciences: Core Technology for Our