allostery and biased signaling are redefining drug design The Long Arc of Chemical Pharmacology The early Opium, for example, was used for dysentery and relief of suffering as early as the 3rd century BC; its Building on Known Pharmacology Medicinal chemists learned early that modifying endogenous molecules — It was early structure-based pharmacology. Dr. Why Terry’s Corner Terry’s Corner is a continuously growing knowledge platform built for scientists

We will be hosting a career panel (more on our panelists soon)! Industry News Data shows nearly 19% weight loss in people with overweight or obesity in Boehringer Ingelheim INV-202, a Peripheral CB1r Blocker for Metabolic Syndrome, at the 83rd American Diabetes Association Scientific Channels, and Transport Proteins (March 24 - 29, 2024) GPCR Jobs Professor in Cardiovascular Pharmacology Scientist I / Scientist II DOE (Native Mass Spectrometry) Senior Vice President of Global Medical Affairs Postdoctoral

serving the global G protein-coupled receptor (GPCR) research community through education, curated scientific GeneTex is offering free antibody samples to the community — not as a promotion, but as a direct scientific “GPCRs present unique challenges for antibody development,” said Alexander Ball, Jr., M.D., Senior Scientist “We see value in situating our antibody efforts within an open scientific dialogue focused on specificity GPCR supports scientists and organizations advancing GPCR biology and GPCR-targeted drug discovery.

Kenakin’s session examines not just how  binding works, but why  so many datasets mislead even seasoned scientists Linear-scale plots appear to plateau early, encouraging premature calls of B max. You may see: Early stopping → potency distortions Different stopping times → incomparable datasets Curve By observing the full onset and offset kinetics, scientists obtain affinity, kinetic rates, and equilibrium Terry Kenakin give scientists an uncommon advantage: the ability to interrogate foundational assumptions

Early bird registration ends on April 18th. Join our upcoming Dr. apply) Save 25% with early bird registration until April 18th. - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs Senior Associate Scientist - Global Research Technologies Novo Nordisk Scientist I - Global Research Technologies Novo Nordisk Postdoctoral Associate Research Technologist I Senior Scientist- Internal Medicine Research Unit Postdoctoral

Highlight Symposium Celebrating Lefkowitz’s 50 Years at Duke Novo Nordisk stops Ozempic kidney trial after early Registration Closed November 15 - 17, 2023 | MPGPCR Conference November 20 - 23, 2023 | ASCEPT Annual Scientific June 2 - 4, 2024 | Chemotactic Cytokines GPCR Jobs NEW Head of Human Resource Business Partners Senior Scientist Senior Director, In vitro pharmacology - Crinetics Pharmaceuticals In vivo Antibody Discovery Research Scientist In Vitro Biologist/Molecular Pharmacologist Senior Vice President, Oncology Clinical Research Scientist

For teams advancing candidates, that means identifying kinetic red flags early, not after expensive safety For teams running early-stage programs, recognizing this decoupling early can sharpen dose optimization Kenakin  will get released next month, featuring real questions from discovery scientists tackling enzyme s Corner and get: Frameworks proven in real discovery programs On-demand lessons  designed for busy scientists

That early curiosity around Family B GPCRs  set a 30-year trajectory in motion, culminating in a scalable for the community. ________________ Keyword Cloud : GPCR-RAMP interactions , Family B GPCRs , GPCR scientist

Early bird registration ends TODAY. Join our upcoming Dr. apply) Save 25% with early bird registration that ends TODAY!! 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Principal Scientist , In vitro pharmacology Senior Associate Scientist - Global Research Technologies Novo Nordisk Scientist I - Global Research Technologies Novo Nordisk Postdoctoral Associate Research Technologist I Senior Scientist

We aim to connect renowned international experts of the field with early career ‘rising stars’.

As of July 31st, early-bird registration for our premium Ecosystem members will begin, allowing you to It is an opportunity to connect with like-minded scientists and researchers and gain valuable insights World Congress of Basic and Clinical Pharmacology GPCR Jobs NEW Senior or Lead Researcher NEW Senior Scientist , Cryo-Electron Microscopy Postdoctoral Research Associate Senior Scientist - Discovery Biotherapeutics Post-Doctoral Fellow/Trainee Scientist; Biochemistry, Cellular and Mechanistic Pharmacology; Lead Discovery

Scientific progress doesn’t guarantee startup success; strategic clarity does. Here are the three most common sources of internal drift in early biotech teams: 1️⃣ Scientific versus A milestone is not a scientific phase. They have strong early data and an even stronger burn rate. Everyone’s busy. No one’s clear. But if you catch it early and fix it decisively, alignment becomes one of your strongest strategic assets

“They offer more than assays—they build true scientific partnerships that help teams get the most from “Through this collaboration, we look forward to sharing scientific insight, best practices, and real-world GPCR and Eurofins DiscoverX aim to accelerate GPCR-targeted drug discovery by connecting scientists with GPCR empowers scientists and organizations advancing GPCR biology and GPCR-targeted drug discovery.

GPCR University Early-Bird Registration Now Open for Premium Members! Connect with fellow scientists and dive into the latest in adhesion GPCR biology. Sponsorship Opportunities: Boost your brand’s visibility at this scientific event. Jobs NEW Postdoctoral Position NEW Postdoctoral research position Senior or Lead Researcher Senior Scientist , Cryo-Electron Microscopy Postdoctoral Research Associate Senior Scientist - Discovery Biotherapeutics

25% off early bird discounts on upcoming classes. Check out what’s coming in September and October: Sign up for both courses now and score a 25% early new GPCR ligands Key elements of a comprehensive and effective GPCR discovery strategy Exclusive 25% Early City Dates : October 23-25, 2024 Join us in the vibrant heart of Mexico City to connect with fellow scientists mechanosensing   Postdoctoral Position Postdoctoral research position Senior or Lead Researcher   Senior Scientist

Disorder Gabab Positive Allosteric Modulator Discovery Collaboration Domain Therapeutics strengthens Scientific ERNEST GPCR early career investigator (ECI) Zoominar Survey 2nd ERNEST Training School – February 20th

In the run-up to the meeting, she sat down with several of the scientists presenting and teaching this Speaker Spotlight Ahead of the meeting, we sat down with four of the scientists presenting and teaching Kris Borzilleri, Pfizer A familiar face from last year, Kris Borzilleri is a longtime discovery scientist Expect deep, practical treatment of affinity and efficacy, allosteric protein function, early safety,

the library ➤ Five Live GPCR Masterclasses Before Summer All included in Premium , each one a direct scientific exchange with a leading scientist, with full replay access afterward. GPCR is the intelligence and community for GPCR scientists.

For Biotech Founders, the real danger is not running out of money, but losing financial control early Why biotech founders do not see the warning signs early enough 👉 The core problem is not that biotech In early-stage biotech, progress is measured through science. Experiments advance. Data improves. It is an early strategic intervention . Reexamining commitments while they are still reversible. Those who do not end up reacting. ✅ Control is about how early clarity is regained.

. 👉 The real mistake is not scientific; it’s strategic . Founders often assume that regulatory readiness is just a matter of scientific progress . remarkably consistent in where they look. 👉 Here’s what the FDA is actually optimizing for, and where most early-stage Then you work upstream to define what your preclinical and early clinical data must demonstrate. But you do need a framework for identifying and addressing regulatory gaps early .

analysis reinforces consistent reduction in risk of recurrence across key subgroups of patients with early Registration Closed November 15 - 17, 2023 | MPGPCR Conference November 20 - 23, 2023 | ASCEPT Annual Scientific June 2 - 7, 2024 | Chemotactic Cytokines GPCR Jobs Head of Human Resource Business Partners Senior Scientist Senior Director, In vitro pharmacology - Crinetics Pharmaceuticals In vivo Antibody Discovery Research Scientist In Vitro Biologist/Molecular Pharmacologist Senior Vice President, Oncology Clinical Research Scientist

process behind discovering new drugs, breaking down the science into accessible, engaging insights for early meaningful therapeutic outcomes Terry’s unique ability to combine storytelling, real-world experience, and scientific

Remember, the early-bird registration and Abstract submission deadline is September 8, and the final , 2023) GPCR Retreat (November 2 - 4, 2023) MPGPCR Conference (November 15 -17, 2023) ASCEPT Annual Scientific Laboratory Specialist Associate NEW Postdoc Research Associate Director, Regulatory Affairs Research Scientist /Senior Scientist I - Molecular Pharmacology Director, Clinical Data Management Director, Discovery Toxicology

But here’s the truth: too many programs still fail because early decisions were built on shaky mechanistic Misjudging orthosteric vs allosteric behavior can derail dose selection, lead to false negatives in early Watch our new trailers for a preview of expert-led GPCR training designed for scientists and drug hunters gives you:   📚 Proven frameworks for real-world discovery 🌍 Flexible, on-demand lessons for busy scientists

Scientists, investors, and CRO professionals fly in from around the world, while Boston’s own vibrant Huntington Ave in Boston 📅 Date:  September 24, 2025 ⏰ Time:  6-8 pm EST 👥 Capacity:  Space is limited — early It’s a curated room of GPCR biotech leaders, scientists, and investor professionals  — and space is limited

Lefkowitz's Career at Duke October 3, 2023, | FREE Seminar: Changing paradigm on Therapeutics targeting Registration Closed November 15 - 17, 2023 | MPGPCR Conference November 20 - 23, 2023 | ASCEPT Annual Scientific Exhibition June 2 - 4, 2024 | Chemotactic Cytokines GPCR Jobs NEW In vivo Antibody Discovery Research Scientist NEW In Vitro Biologist/Molecular Pharmacologist Senior Vice President, Oncology Clinical Research Scientist

your contributor articles with the community, stay updated with GPCR literature, network with GPCR scientists and Shalini Sharp to its Board of Directors GPCR Events, Meetings, and Webinars February 20, 2024 | Career Pharmacology 2026 GPCR Jobs NEW Director of Laboratory Operations - Single-molecule Imaging Center NEW Scientific Assistant Postdoctoral Fellowship- Mechanistic Biology Research Scientist Post-Doc position Lead Researcher

articles with the community, stay updated with GPCR literature, join a dynamic team, network with GPCR scientists will be at the Oxford Global’s Biologics event GPCR Events, Meetings, and Webinars February 20, 2024 | Career July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Senior Scientist Pharmacology of Feeding Behavior Director of Laboratory Operations - Single-molecule Imaging Center Scientific Assistant Postdoctoral Fellowship- Mechanistic Biology Research Scientist Join Dr.

GPCR Ecosystem perks, including our forums, private groups, and all Ecosystem members Extended early Take advantage of the early bird registration until April 18th, 2024, to save 25%! GPCRs: Structure, Mechanisms, Disease, and Pharmacology Industry News Monash University pharmaceutical scientists Basic and Clinical Pharmacology 2026 GPCR Jobs Postdoctoral Associate Research Technologist I Senior Scientist Pharmacology of Feeding Behavior Director of Laboratory Operations - Single-molecule Imaging Center Scientific

The symposium will feature a trainee day with a career panel. Remember to subscribe to Dr. March 24 - 29, 2024) GPCR Jobs NEW Senior Research Specialist - Natural Sciences - Surgery NEW Senior Scientist Computational Protein Design (GPCR) Postdoctoral Fellow, Caron Lab Clinical Trial Associate Research Scientist /Senior Scientist I - Molecular Pharmacology Explore Dr.