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- Misread the Curve, Misjudge the Drug: Rethinking Antagonism in GPCR Pharmacology
Schild and Gaddum equations offer early frameworks for quantifying these effects but modern curve-fitting when irreversible binding, receptor reserve, or allosteric effects mimic classical patterns —leading scientists over upcoming topics Who it’s for: drug discovery teams, pharmacologists refining their toolkit, and scientists
- GPCR News Flash! Top Updates You Can't-Miss! + University CheatSheet is finally available! ❄ Dec 2 - 8, 2024
We've got an early holiday treat for you: The University CheatSheet ! 2026 | 20th World Congress of Basic and Clinical Pharmacology GPCR Jobs GPCR Molecular Pharmacologist Scientist - Biology Scientist I Cell Biology - Tectonic Therapeutic Senior Principal Scientist, Medicinal Chemistry PhD fellowship in GPCR mechanosensing Senior Scientist, GPCR Pharmacology Research Associate - Professor
- 📰 GPCR Weekly News, August 28 to September 3, 2023
Please remember that the early-bird registration deadline ends tomorrow, the abstract submissions deadline 2023 | GPCR Retreat November 15 - 17, 2023 | MPGPCR Conference November 20 - 23, 2023 | ASCEPT Annual Scientific Research Laboratory Specialist Associate Postdoc Research Associate Director, Regulatory Affairs Research Scientist /Senior Scientist I - Molecular Pharmacology Explore Dr.
- 📰 GPCR Weekly News, July 3 to 9, 2023
This year's symposium will feature a trainee day with a career panel. March 24 - 29, 2024) GPCR Jobs NEW Postdoctoral Fellow, Caron Lab NEW Clinical Trial Associate Research Scientist /Senior Scientist I - Molecular Pharmacology Vice President, Medical Affairs Associate Director / Director
- Exploring the Breakthroughs in GPCR Research
Early-bird registration for premium Ecosystem members opens on July 31st, so mark your calendars and Join fellow scientists and researchers in person to stay updated with adhesion GPCR biology. Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Postdoctoral Research Associate Senior Scientist - Discovery Biotherapeutics Post-Doctoral Fellow/Trainee Scientist; Biochemistry, Cellular and Mechanistic Director GPCR Drug Discovery Biologist Post-Doctoral Scientist- Molecular Pharmacology (FDE) Join Dr.
- 📰 GPCR Weekly News, February 12 to 18, 2024
articles with the community, stay updated with GPCR literature, join a dynamic team, network with GPCR scientists Farma will be at Bio Europe Spring in Barcelona GPCR Events, Meetings, and Webinars February 20, 2024 | Career Pharmacology of Feeding Behavior Director of Laboratory Operations - Single-molecule Imaging Center Scientific Assistant Postdoctoral Fellowship- Mechanistic Biology Research Scientist Post-Doc position Join Dr.
- GPCR Updates: Celebrating Breakthroughs, New Course Launches Soon, and Exclusive Discounts! | Aug 26 - Sep 1, 2024
Premium members can enjoy a 25% OFF early bird discount , but hurry - it's only available for a limited Special Offer for Scientists who work and live in developing countries If you live and work in a developing Don’t miss this chance to benefit from our early bird pricing and premium content. Associate - Professor Graeme Milligan NEW Postdoc in Molecular Pharmacology - The Hauser Group NEW Senior Scientist /Staff Scientist, Computational Chemistry Postdoc in GPCR mechanosensing Postdoctoral Position Postdoctoral
- 📰 GPCR Weekly News, April 22 to 28, 2024
GPCR Ecosystem Premium Membership (restrictions apply) Early bird discount on future courses (restrictions GPCR Matchmaking Did you check out our first job opportunity spotlight for a Principal Scientist In Vitro Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Post Doctoral Fellow Postdoc Position Principal Scientist , In vitro pharmacology Senior Associate Scientist - Global Research Technologies Novo Nordisk Scientist I - Global Research Technologies Novo Nordisk Postdoctoral Associate Research Technologist I Senior Scientist
- 📰 GPCR Weekly News, April 15 to 21, 2024
GPCR Ecosystem Premium Membership (restrictions apply) Early bird discount on future courses (restrictions GPCR Matchmaking Did you check out our first job opportunity spotlight for a Principal Scientist In 20th World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Postdoc Position Principal Scientist , In vitro pharmacology Senior Associate Scientist - Global Research Technologies Novo Nordisk Scientist I - Global Research Technologies Novo Nordisk Postdoctoral Associate Research Technologist I Senior Scientist
- GPCR Drug Discovery at Discovery on Target: Why This Track Is About More Than Receptors
. 💡 Why This Matters — Even If You’re Not a GPCR Scientist GPCR pathways intersect with oncology, CNS Whether you’re in early discovery or clinical development, the strategies here could open doors in your forward — together. 🚨 Mark your calendar for the GPCR Happy Hour Join us at GPCR Happy Hour , where scientists
- Dr. Peter Robert Banks - Dr. GPCR Podcast
Peter Banks, Scientific Director at BioTek Instruments! Learn about his career today!
- 📰 GPCR Weekly News, June 26 to July 2, 2023
The exciting news is that this Symposium will be a trainee day with a career panel. Interactions of GPCRs, Ion Channels, and Transport Proteins (March 24 - 29, 2024) GPCR Jobs NEW Research Scientist /Senior Scientist I - Molecular Pharmacology NEW Vice President, Medical Affairs NEW Associate Director / Director, Clinical Operations Professor in Cardiovascular Pharmacology Scientist I / Scientist II
- Dr. GPCR Spotlights Revvity’s pHSense™ Internalization Tools
scalability for high-throughput screening Low sensitivity in detecting endogenous GPCRs With pHSense™, scientists shares the story behind pHSense , including its application in real-time internalization assays and the scientific Through our podcast, training programs, and partner content, we help scientists connect, collaborate,
- High-Content Screening for GPCR Programs: Overcoming Assay Limitations with Fluorescent Ligands
infrastructure Safer and more sustainable workflows For GPCR researchers aiming to reduce ambiguity in early hit-finding, the shift from radioligands to fluorescent HCS assays offers substantial scientific and Early optimization prevents later variability and sets the foundation for scalable screening. 2. Key scientific advantages include: Physiological Relevance Fluorescent ligand binding occurs in intact tools accelerate hit validation, reduce ambiguity, and support more data-driven decision-making across early
- Is Your GPCR Drug Discovery Program Built for Breakthroughs or Breakdowns?
going fast" and focusing only on the science, burns through precious capital and time, leaving both scientific It’s the fundamental framework for building your Precision Blueprint , ensuring every scientific detail Part 2: The Data Disconnect : Discover how fragmented, unmanaged GPCR data cripples scientific progress Part 3: The Financial Friction : Explore how a lack of precise alignment between GPCR scientific milestones Learn to tie your program's progress directly to your funding runway, incorporating crucial early commercial
- 📰 GPCR Weekly News, March 4 to 10, 2024
Classified GPCR News from March 4th to 10th, 2024 GPCR Activation and Signaling Glu1022.53-Mediated Early World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Research Technologist I Senior Scientist Pharmacology of Feeding Behavior Director of Laboratory Operations - Single-molecule Imaging Center Scientific
- What If Your Data is Lying to You? The Calcium Assay Dilemma
this foundational lesson, Terry Kenakin dives deep into a widely used, often misunderstood tool in early agonists can be drastically underestimated—potentially leading promising leads to be dismissed too early
- Embark on a GPCR Adventure: Your Weekly Research Expedition! | Oct 21-27, 2024
Informs the Development of Drugs Targeting G Protein-Coupled Receptors Olfactive Biosolutions Establishes Scientific Summit Europe July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology GPCR Jobs Scientist I Cell Biology - Tectonic Therapeutic PhD fellowship in GPCR mechanosensing Senior Scientist, GPCR Pharmacology Scholar – iPSC in cardiac and endothelial cell function Protein Biochemist/Structural Biologist Senior Scientist /Staff Scientist, Computational Chemistry GPCR Activation and Signaling A gain of function variant in
- 📰 GPCR Weekly News, September 18 to 24, 2023
Lefkowitz's Career at Duke October 3, 2023, | FREE Seminar: Changing paradigm on Therapeutics targeting Registration Closed November 15 - 17, 2023 | MPGPCR Conference November 20 - 23, 2023 | ASCEPT Annual Scientific 4, 2024 | Chemotactic Cytokines GPCR Jobs NEW Senior Vice President, Oncology Clinical Research NEW Scientist
- From Multiplex to Models: Scaling Up GPCR Discovery in the Post-Silo Era
Watch Episode 167 Today’s GPCR scientists don’t want to study one interaction, they want to model the The newest scientists want scalable, automated systems and the tools to move from data collection to deorphanization Ligand screening and functional validation Training the Next Wave Graduate students and visiting scientists Listen to the complete episode to learn more. _________________ Keyword Cloud : GPCR scientist network
- 📰 GPCR Weekly News, May 1 to 7, 2023
Precision Medicine is critical, we cannot think about one size fits all” Dr Pina Cardarelli, Chief Scientific Annual Meeting IRN I-GPCRNet (October 25 - 27, 2023) GPCR Jobs Vice President, Medical Affairs Associate Scientist - Technology Senior Research Scientist/Principal Scientist- Technology Tissue Culture Scientist/Tissue Culture Manager Postdoctoral Researcher Director - Targeted Oncology Senior Scientist - Antibody Engineering Scientist—Immuno-Oncology Convergent Research - Senior Scientist, Cell-Based Assay Development Explore
- Inside Out: Mapping GPCRs from Membrane Codes to Market Moves
biased NTSR1 modulator targets pain without the need for opioids, and a real-time lipid probe tracks early Biased NTSR1 Modulator for Non-Addictive Pain Relief A Cell-Permeable Fluorescent Probe Illuminates Early
- Assay Sensitivity: The Hidden Lever Driving GPCR Drug Discovery
Pipeline Payoff: Assay Sensitivity for Better Predictions For drug discovery scientists, time and predictive Every mischaracterized compound that enters animal studies or early trials is a tax on time and resources Why Members Join: Frameworks proven in discovery programs On-demand lessons built for busy scientists
- GPCR Allosteric Modulation: Why Allostery is the Engine of Drug Discovery
lead candidates Underestimation of in vivo potency Kenakin explains why recognizing this phenomenon early Scientists acting on today’s insight will shape tomorrow’s breakthroughs. 40 years of expertise at your
- 📰 GPCR Weekly News, June 5 to 11, 2023
GPCRs in Neuroscience Early pheromone perception remodels neurodevelopment and accelerates neurodegeneration Drug Interactions of GPCRs, Ion Channels, and Transport Proteins (March 24 - 29, 2024) GPCR Jobs NEW Scientist I / Scientist II DOE (Native Mass Spectrometry) Senior Vice President of Global Medical Affairs Postdoctoral
- Dr. GPCR and Celtarys Research Join Forces to Expand Access to Innovative GPCR Tools
high-resolution binding studies, kinetic analysis, and live-cell imaging, empowering both academic and industrial scientists “These tools can dramatically improve how scientists measure ligand-receptor interactions, visualize GPCR provides a unique platform to reach scientists at every stage of GPCR research,” said Wilson Gomes GPCR empowers scientists and companies advancing receptor biology and drug discovery.
- Dynamic GPCR activation revealed through time-resolved Cryo-EM
This early interaction sets the stage for a cascade of significant conformational changes. With this high-resolution, dynamic view of GPCR activation, scientists can better tackle diseases by
- 📰 GPCR Weekly News, October 23 to 29, 2023
Heptares Zoom Webinar November 15 - 17, 2023 | MPGPCR Conference November 20 - 23, 2023 | ASCEPT Annual Scientific Europe 2024 Conference and Exhibition June 2 - 7, 2024 | Chemotactic Cytokines GPCR Jobs NEW Staff Scientist of Health and Medical Sciences NEW Octant Apprentice Head of Human Resource Business Partners Senior Scientist Senior Director, In vitro pharmacology - Crinetics Pharmaceuticals In vivo Antibody Discovery Research Scientist
- Embark on a GPCR Adventure: Your Weekly Research Expedition! | Oct 21-27, 2024
Summit Europe July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology GPCR Jobs Scientist I Cell Biology - Tectonic Therapeutic Senior Scientist, GPCR Pharmacology Research Associate - Professor Scholar – iPSC in cardiac and endothelial cell function Protein Biochemist/Structural Biologist Senior Scientist /Staff Scientist, Computational Chemistry Postdoc in GPCR mechanosensing GPCR Activation and Signaling
- Community guidelines for GPCR ligand bias: IUPHAR review 32
Here, we provide guidelines and terminology for any scientists to design and report ligand bias experiments Scientific insight, biosensors, and analytical methods are still evolving and should benefit from and




















