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Screening technologies, structure-informed design, and AI are accelerating target selection. Terry’s Corner is designed to shorten that distance between initial promise and actionable clarity. This expands the strategic toolbox for discovery teams: Bias isn’t an “optional property” to design in Weekly lectures  that sharpen your command of how enzyme activity drives pharmacokinetics and drug design

GPCR Jobs Computational drug design PhD student at the Department of Drug Design and Pharmacology Computational drug design postdoc at the Department of Drug Design and Pharmacology Software / database development PhD student at Department of Drug Design and Pharmacology Software / database development postdoc at the Department of Drug Design and Pharmacology Postdoc in Bioinformatics/Data Science at Department of Drug Design and Pharmacology Scientist/Senior Scientist (Research Software Engineer) Senior Scientist

dramatically improve how scientists measure ligand-receptor interactions, visualize binding in live cells, and design generation of conjugates, such as labeled ligands, with excellent affinity and pharmacological profiles, designed

It’s 40 years of hard-won insight distilled into accessible, high-impact content designed for learners

Yamina’s Corner delivers GPCR consulting that cuts through the noise, designing assay cascades, setting chemokines and their receptors drive selectivity and promiscuity, paving the way for rational ligand design

A GPCR Internalization Tool Designed for Real Research Needs Built on more than two decade A GPCR Internalization Tool Designed for Real Research Needs s of GPCR assay innovation , pHSense™  was developed to overcome

Some drugs take hours to reach equilibrium—not because of poor design, but because the system is fluid Why you need to be there: Learn how kinetic nuance shapes ligand design.   lectures, classified industry news, priority event alerts, job opportunities, and insider commentary—designed

to decision faster, with fewer false starts   This isn’t textbook material—it’s real-world expertise designed The analytical tools that shaped traditional affinity analysis were designed for simpler systems.

ability to accurately predict protein structures is transformative for identifying new drug targets and designing The AlphaFold database encompasses over 200 million proteins, aiding structural biology, protein design Furthermore, AI's role in structural biology and drug design is set to spark innovation in automated

Founded as a spinout from the University of Dundee on 20 July 2012, Exscientia pioneered the design of We have achieved a great deal in the last decade, such as the first-ever AI-designed drug candidates We’re excited about delivering the next ten years of Exscientia and advancing AI to design better drugs

October 2022 "Pepducins are small-lipidated peptides designed from the intracellular loops of G protein-coupled To date, pepducins designed from numerous GPCRs have been studied for their impact on pathologic conditions This review will focus in particular on pepducins designed from protease-activated receptors, C-X-C motif

GPCR Jobs Computational drug design PhD student at the Department of Drug Design and Pharmacology Computational drug design postdoc at the Department of Drug Design and Pharmacology Software / database development PhD student at Department of Drug Design and Pharmacology Software / database development postdoc at the Department of Drug Design and Pharmacology Postdoc in Bioinformatics/Data Science at Department of Drug Design and Pharmacology Scientist/Senior Scientist (Research Software Engineer) Senior Scientist

This isn't just another lecture series; it's a practical tool designed to help you recognize and build

By using donor-acceptor pairs with different emission spectra that don’t overlap, researchers can design This assay utilized our fluorescent ligand, CELT-335 , designed for hCB 1 /CB 2  cannabinoid receptors power of HTRF and other FRET-based technologies by providing high-performance fluorescent ligands designed

Why Asking Better Questions in Science Improves the Work Itself For JB, questions fuel the way he designs In his collaboration with David Hodson, every major leap—from early ligand design to GPCR visualization

for what would become the evolution of GPCR research — a transformation that reshaped how scientists design Today, success depends less on manual precision and more on experimental design, data interpretation,

empowerment , not micromanagement He hired based on attitude and team fit , not just credentials He designed

. -            Fluorescent probe design for specific targets:  Not all targets have available high-affinity If you are curious about fluorescent probes, fluorescent probe design or GPCR tools, feel free to contact

uncomfortable truth: 👉 Your biotech is already running on an operating cadence you didn’t consciously design They drift because their cadence isn’t designed.

chemical structure of the lead compounds to improve potency and selectivity, thereby optimising the drug's design Furthermore, understanding these resistance mechanisms enables the design of next-generation drugs that It also helps in combination therapy strategies, where drugs are designed to target multiple sites or

Johannes Broichhagen explains how next-generation fluorescent probes—designed with precise synthetic His work shows why chemical design can outperform antibodies and how rigorous assay validation bridges

discovery has the potential to accelerate the identification and development of novel drugs, optimize drug design compared; and 3) detection, prediction, or generation (e.g. prediction of a protein structure, or ligand design De novo drug design: AI algorithms can generate new molecules with desired properties, such as binding Multi-target drug design: GPCRs are often involved in complex signaling networks. With the revolution of biased signalling of GPCRs comes the possibility of designing drugs that selectively

Instead of creating another black-box assay, they designed pHSense around rare-earth europium probes. The Chemistry That Almost Didn’t Work Designing pH-sensitive rare-earth complexes was not an obvious

Structure-based design  powered by cryo-EM and AI. 🔬 Inside the GPCR Track Agenda Expect deep dives is more than an academic experience — it’s like being handed a new set of tools to rethink your drug design

Rock your favorite design, spark conversations in the lab, and help power everything we build—one mug

It’s about finding purpose through loss, choosing academia when many peers walk away, and designing science potencies in seized samples, drug combinations that mirror contamination patterns, and experimental designs

Some innovative solutions have been the development of the BERKY and the ONE-GO biosensors, designed The ONE-GO biosensors, designed in a single vector, incorporate a G protein tagged with a YFP acceptor M., et al., Revealing the Activity of Trimeric G-proteins in Live Cells with a Versatile Biosensor Design

crystallography and cryo-EM have resulted in a wealth of GPCR structures that have been used in drug design

That meant simulations, ligand screening, and experimental design could move forward with confidence.

Startups Play by Different Rules — and Most Scientific Founders Miss That   A research lab is designed A startup is designed for progress.