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Results found for "Timo De Groof"
- Coordinated transcriptomics and peptidomics of central nervous system identify neuropeptides and ...
expression patterns of these 98 genes in various larval tissues were evaluated using quantitative real-time
- Molecular creativity in drug discovery
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- Enhancing GPCR Research Outreach | Dr GPCR University early-bird registration ends soon!
cellular assays to analyze GPCR ligand behavior Predicting activity and in vivo target coverage with real-time
- 📰 GPCR Weekly News, June 10 to 16, 2024
cardiac drug development GPCRs in Neuroscience Astrocytic PAR1 and mGluR2/3 control synaptic glutamate time
- Radioligands vs. Fluorescent Ligands: Binding Assays
high-affinity radioligands, but with the development of potent fluorescent probes, this gap can filled in a timely
- β2-Adrenergic Receptor Expression and Intracellular Signaling in B Cells Are Highly Dynamic during..
signal-regulated kinase 1/2 (ERK1/2) and cAMP response element-binding protein (CREB)) were analyzed at different time
- How GPCR Collaboration Built an Innovation Engine
Timing, leadership alignment, and a critical mass of motivated scientists converged.
- Innovative Data-Driven Solutions: The pHSense Revolution
For the first time, a team demonstrated high-throughput internalization data in physiologically relevant
- How Breakthroughs Happen: Eric Trinquet on Innovation, Serendipity & GPCRs
It’s about timing, teaming, testing, and failing smarter. 🚀 Why This Matters: Whether you’re launching
- Dimerization of GPCRs: Novel insight into the role of FLNA and SSAs regulating SST2 and SST5...
internalize both receptors whereas pasireotide promoted robust receptor internalization at shorter times
- The Impact of CB1 Receptor on Nuclear Receptors in Skeletal Muscle Cells
Quantitative real-time probe-based polymerase chain reaction (qRT-PCR) assays are deployed in order to
- How to Use Statistical Methods to Strengthen Every GPCR Drug Discovery Decision
Trusting your eyes—or tradition—can cost time, money, and credibility.
- Chemical Drug Matter : Rethinking the Molecules We Choose to Develop In Drug Discovery
Yet, far less time is spent scrutinizing the structural logic and origin of the molecules we screen
- Assay Volume Control: Your GPCR Drug Discovery Power Lever
It’s built to compress your time to clarity—so you can pick better targets, stress-test hypotheses earlier
- Curve Shifts Don’t Lie, But Your Eyes Might
For high-throughput screens where sensitivity isn’t critical, you’ll save time by running fewer replicates
- How Collaboration Drives GPCR Discoveries
By the time his lab began dissecting the GLP-1 and GIP receptor landscape in islets and brain, the signal
- TM5-TM6: structural switches that modulate the coupling of serotonin receptors to Gs or Gi
Likewise, in this work the authors identify for the first time the specific amino acids that modulate
- Decoding Schild Analysis: The Pharmacologist’s Lens on Competitive Antagonism
Slopes >1 often mean incomplete equilibration; lower antagonist concentrations haven’t had enough time
- A Note from Yamina: Building the Next Chapter of Dr. GPCR
For the first time, University courses will be included in Premium Membership , giving members full access
- Understanding Enzyme Inhibition In GPCR Discovery Programs
Instead of chasing fragmented feeds, you get a single, credible source that respects your time and advances
- 📰 GPCR Weekly News, July 17 to July 23, 2023
Premium members can always go back and watch the recorded talks at any time.
- Why Opposing Processes Matter for Your Next GPCR Drug
Ignore these forces, and your “selective” agonist may deliver surprises the first time it meets a patient
- 📰 GPCR Weekly Buzz: Exciting Schedule Shifts for Principles of Pharmacology I & II | August 12-18, 2024
October 31, November 7 - 14 -21, and December 5, 2024 (five sessions) Topics: New cellular assays, real-time
- 📰 GPCR Buzz: August 5-11, 2024 | Top Highlights from DrGPCR University!
cellular assays to analyze GPCR ligand behavior Predicting activity and in vivo target coverage with real-time
- Mechanism vs. Assumption: A Model-First Path to Getting GPCR MoA Right
Hi GPCR Community, If you work on GPCR discovery, you already know: early signals can mislead, and timing
- Dr. GPCR University registration is now open! Secure your spot now!
Essentials for effective GPCR discovery Discover: Advanced cellular assays for GPCR ligand behavior Real-time
- 📰 GPCR Weekly News, April 3 to 9, 2023
Local 5-HT signaling bi-directionally regulates the coincidence time window for associative learning.
- Transformative GPCR Insights: Unleash New Horizons in Science | Sep 9 - 15, 2024
Topics: New cellular assays, real-time kinetics, and unique GPCR behaviors.
- 📰 GPCR Weekly News, September 18 to 24, 2023
couldn't make it, no sweat – our premium members can always go back and watch the recorded talks at any time
- 📰 GPCR Weekly News, September 11 to 17, 2023
GPCR Activation and Signaling Characterization of the real-time internalization of nine GPCRs reveals




















