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- From Multiplex to Models: Scaling Up GPCR Discovery in the Post-Silo Era
Watch Episode 167 Today’s GPCR scientists don’t want to study one interaction, they want to model the Compatible with multiple readouts: proximity, immuno assays, pulldowns Validated antibodies + digital search protein interactions (e.g., 14-3-3) Heterodimerization Endogenous vs. overexpressed systems Orphan GPCR Listen to the complete episode to learn more. _________________ Keyword Cloud : GPCR scientist network , GPCR online course , GPCR data platform , multiplex assays , GPCR drug discovery
- 📰 GPCR Weekly News, February 12 to 18, 2024
have a poster session in breakout rooms on Zoom; if you are interested in sharing your work with our community You'll share your contributor articles with the community, stay updated with GPCR literature, join a in GPCR Pharmacology: Unraveling the Secrets of Cellular Communication Bowes Biomedical Investigator Takes Aim at Cracking Cellular Communication Code Aelis Farma will be at Bio Europe Spring in Barcelona World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Research Fellow NEW Postdoctoral
- Beyond the Probe: Scaling Innovation From the Bench to Product Launch
Their method allows researchers to explore different linker positions, tailor activity (agonist or antagonist GPCR ecosystem , Celtarys is opening up that model to the broader research community. The goal? . _______________ Keyword Cloud: GPCR data platform , fluorescent ligands , assay development , GPCR research community , Dr. GPCR ecosystem , GPCR webinar series
- 📰 GPCR Weekly News, January 22 to 28, 2024
Please email us at Hello@DrGPCR.com if you want to share your work with our community. We’ll send your contributor articles to our community, keep you updated with GPCR papers, receive support Hemicyanine as a "Turn-On" Fluorescence Probe Industry News Domain Therapeutics awarded Hospital-University Research World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs Post-Doc position Lead Researcher Senior Researcher in Structural Biology Post-Doctoral Fellow Postdoctoral Fellow Research Laboratory Specialist
- 📰 GPCR Weekly News, June 3 to June 9, 2024
15 insightful research papers and industry updates. Stay informed with the most recent developments in GPCR research and industry news. Join the global GPCR community to present your research—submit your abstract using this form. Research ORP9-PH domain-based fluorescent reporters for visualizing phosphatidylinositol 4-phosphate pharmacology Senior Scientist - Receptor Pharmacology Postdoctoral Scientist Senior Research Associate
- 📰 GPCR Weekly News, May 27 to June 2, 2024
Take a moment to browse our latest coverage of GPCRs this week, featuring 24 insightful research papers Stay informed with the most recent developments in GPCR research and industry news. Join the global GPCR community to share your research—submit your abstract using this form. Research Engineering G protein-coupled receptors for stabilization Cryo-electron microscopy for GPCR research and drug discovery in endocrinology and metabolism Chemogenetic Signaling in Space and Time
- 📰 GPCR Weekly News, January 15 to 21, 2024
one GPCR Event, and two GPCR job ads! Research G-Protein Coupled Receptor Gpr-1 Is Important for the Growth and Nutritional Metabolism of Jude Children’s Research Hospital adds $13 million project to Research Collaboratives Program AIRSUPRA World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Post-Doc position NEW Lead Researcher Senior Researcher in Structural Biology Post-Doctoral Fellow Postdoctoral Fellow Research Laboratory
- 📰 GPCR Weekly News, January 1 to 7, 2024
The newest GPCR research is hot off the press! G protein-coupled receptor Methods & Updates in GPCR Research RediscMol: Benchmarking Molecular Generation Morgan Healthcare Conference Isomorphic Labs Announces Strategic Multi-Target Research Collaboration With Novartis Salipro Biotech announces multi-target research collaboration with an additional Top5 crop World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Postdoctoral Fellow NEW Research
- Allosteric modulation of GPCRs: From structural insights to in silico drug discovery
October 2022 "G protein-coupled receptors (GPCRs) play critical roles in human physiology and are one endogenous ligands (orthosteric site), allosteric modulators offer new avenues for the regulation of GPCR Recent advances in the structure determination of GPCRs bound to different types of allosteric modulators In this review, we provide a systematic analysis of the currently available GPCR structures in complex Read more at the source #DrGPCR #GPCR #IndustryNews
- 📰 GPCR Weekly News, January 8 to 14, 2024
We’ve curated 10 GPCR papers, seven industry news, and two GPCR job ads! This week's highlight: Dr. : Empowering the ML Community in Molecular Predictive Modelling NanoImaging Services Appoints John Rigg World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Senior Researcher in Structural Biology NEW Post-Doctoral Fellow Postdoctoral Fellow Research Laboratory Specialist Associate Postdoctoral GPCR Ecosystem
- 📰 GPCR Weekly News, December 18 to 31, 2023
GPCR Access to Dr. Research Direct Binding Methods to Measure Receptor-Ligand Interactions How accurately can one predict Investigator, In Vitro Biology NEW Associate Scientist Postdoctoral Scholar - O’Neill Lab Junior Research Scientist Postdoctoral Fellow Post-Doc Research Associate Assistant/Associate Professor Explore Dr. GPCR Ecosystem
- Residency time of agonists does not affect the stability of GPCR-arrestin complexes
September 2022 "Background and purpose: The interaction of arrestins with G-protein coupled receptors (GPCRs GPCRs that internalize without arrestin have been classified as "class A" GPCRs whereas "class B" GPCRs The interaction of arrestins with GPCRs requires both agonist activation and receptor phosphorylation Read more at the source #DrGPCR #GPCR #IndustryNews
- 📰 GPCR Weekly News, December 11 to 17, 2023
The latest and greatest in GPCR research is here, this week we’ve curated 14 GPCR papers, 7 industry Ross Cheloha's research involves semi-synthetic nanobody-ligand conjugates with enhanced transcriptional Research Phosphorylation Sites of the Gastric Inhibitory Polypeptide Receptor (GIPR) Revealed by Trapped-Ion-Mobility Lab NEW Junior Research Scientist Postdoctoral Fellow Post-Doc Research Associate Assistant/Associate GPCR Ecosystem
- 📰 GPCR Weekly News, December 4 to 10, 2023
Hi GPCR lovers! in Neuroscience Research progress on the role of orphan receptor GPR139 in neuropsychiatric behaviours Research Transcriptome analysis of Schizothorax oconnori (Cypriniformes: Cyprinidae) oocytes: The role Research Associate NEW Assistant/Associate Professor Principal scientist – oncology biomarker expert Postdoctoral Fellow Scientific Assistant Scientist Lead Researcher Explore Dr.
- 📰 GPCR Weekly News, November 20 to 26, 2023
Research GproteinDb in 2024: new G protein-GPCR couplings, AlphaFold2-multimer models and interface Derivatives: Natural Occurrence, Structural Diversity, and Biological Activity Advances in steroid research Jobs - Contact Mark Schmeizl NEW Scientist NEW Lead Researcher NEW Post-Doctoral Fellow Sr Scientist in Obesity, Muscle, and Metabolism Post-Doctoral Fellow Research Associate I, Tissue Culture Post-Doc Research Associate Postdoctoral Fellow Explore Dr.
- 📰 GPCR Weekly News, March 25 to March 31, 2024
This week's highlight includes congrats to: Junyi Liang, Niña Caculitan, and Adam W Smith for their research If you want to showcase your research, you can submit a poster presentation to our community, take advantage Research Highly efficient GPCR immobilization with enhanced fouling resistance, salt tolerance, and pharmaceutical scientists honoured in NHMRC Research Excellence Awards Domain Therapeutics to Present World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs Postdoctoral Associate Research Technologist
- Class B1 GPCR Dimerization: Unveiling Its Role in Receptor Function and Signaling
While GPCRs can exist as monomers, some types, like class C GPCRs, are obligate dimers, either as homodimers Class B1 GPCRs are an important subclass of GPCRs that include 15 receptors involved in regulating body Research using techniques like bioluminescence resonance energy transfer (BRET) and fluorescence resonance In summary, dimerization in class B1 GPCRs is an emerging area of research that has far-reaching implications Nature Communications, 2024. 15 (1): p. 4390. 7.
- Identification of GPCRs Modulating Flow-induced Signaling Pathways in Vascular Endothelial Cells
Brian Arey is doing. https://www.ecosystem.drgpcr.com/dr-gpcr-virtual-cafe/ #gpcr #drgpcr #virtualcafe
- 📰 GPCR Weekly News, November 13 to 19, 2023
Adhesion GPCRs CryoEM structures of adhesion in GPCR CD97: Filling in some of the gaps GPCR Activation Research Optogenetic Microwell Array Screening System: A High-Throughput Engineering Platform for Genetically Announces Settlement of INGREZZA Abbreviated New Drug Application (ANDA) Litigation PostEra Announces a Research Jobs NEW Sr Scientist in Obesity, Muscle, and Metabolism NEW Post-Doctoral Fellow NEW Research Associate I, Tissue Culture Post-Doc Research Associate Postdoctoral Fellow Research Scientist/Postdoctoral Associate
- Anatomy of a partnership: Cancer Research UK teams up with Sosei Heptares
August 2022 "August 10, 2022 Cancer Research UK is working with global biopharma Sosei Heptares on a Cancer Research UK, a charity dedicated to funding lifesaving oncology research, spent £388 million on cancer research last fiscal year. Much of that funding is distributed to support third party research, but the group also does its own Read more at the source #DrGPCR #GPCR #IndustryNews
- Statin-induced increase in actin polymerization modulates GPCR dynamics and compartmentalization
regulating the dynamics of the serotonin1A receptor, a crucial neurotransmitter G protein-coupled receptor (GPCR in understanding the modulatory role of the membrane environment on the organization and dynamics of GPCRs Read more at the source #DrGPCR #GPCR #IndustryNews
- 📰 GPCR Weekly News, February 26 to March 3, 2024
Sandra Berndt, Ines Liebscher, and Susanne Horn et. al for their for their research on adhesion GPCR If you want to share your work with our community, please don’t hesitate to fill out this form. Research Cryo-electron microscopy for GPCR research and drug discovery in endocrinology and metabolism Illinois Septerna divulges new TSHR antagonists for hyperthyroidism Unlocking the Secrets of Cellular Communication : The Revolutionary Impact of Cryo-EM on GPCR Research GPCR Events, Meetings, and Webinars March 13 -
- 📰 GPCR Weekly News, October 2 to 8, 2023
Hello GPCR people! Check out our GPCR roundup now, and be the first to read! their new research. Research Functional GPCR expression in eukaryotic LEXSY system Structural and Molecular Insights into Scientist (level I or II) Research Fellow Research Technician II - Surgery Post-Doc Research Associate Research Technician Explore Dr.
- Dynamic GPCR activation revealed through time-resolved Cryo-EM
Human cells express over 800 G-protein-coupled receptors (GPCRs) to facilitate communication with the complex with the β2-adrenergic receptor (β2AR) at brief sequential intervals following GTP addition, the research This research not only deepens our understanding of a key biological process but also provides a valuable map for pharmaceutical researchers to design new therapies. Time-resolved cryo-EM of G-protein activation by a GPCR. Nature (2024).
- 📰 GPCR Weekly News, October 9 to 15, 2023
Read about the newest discoveries in GPCR research 🙌 Save the dates: November 2 - 4: We're sponsoring Pharmaceuticals Senior Director, In vitro pharmacology - Crinetics Pharmaceuticals In vivo Antibody Discovery Research Scientist In Vitro Biologist/Molecular Pharmacologist Senior Vice President, Oncology Clinical Research Scientist (level I or II) Research Fellow Research Technician II - Surgery Explore Dr. GPCR Ecosystem
- 📰 GPCR Weekly News, October 16 to 22, 2023
Bianca Plouffe and their colleagues' research on 'β-arrestin-dependent and -independent endosomal GPCR shapes behavior Methods & Updates in GPCR Research Advancements in the use of xenopus oocytes for modelling Pharmaceuticals Senior Director, In vitro pharmacology - Crinetics Pharmaceuticals In vivo Antibody Discovery Research Scientist In Vitro Biologist/Molecular Pharmacologist Senior Vice President, Oncology Clinical Research GPCR Ecosystem
- Unlocking the Therapeutic Potential of Previously Undruggable GPCRs
The GPCR Opportunity GPCRs are the largest and most diverse group of membrane receptors. A New Wave of GPCR Drug Discovery GPCRs are considered highly druggable, with GPCR-targeting therapeutics , the biotech investment community has injected significant funding into small biotech companies developing The Future of GPCR Research GPCRs are a very important class of drug targets, but despite historical Orion has entered a strategic research collaboration with Peptilogics, a US-based AI drug discovery company
- 📰 GPCR Weekly News, September 11 to 17, 2023
Hello GPCR people! Check out our GPCR roundup now, and be the first to read! Graeme Milligan and their colleagues research on Pro-phagocytic function and structural basis of GPR84 and Signaling Protein Research Tools First-In-Class Drug Shows Potential for Treatment of Cannabis Use Jobs NEW Research Technician II - Surgery NEW Post-Doc Research Associate NEW Research Technician Senior Trafficking Postdoctoral Fellow Researcher / Senior Researcher in Structural Biology Research Specialist
- 📰 GPCR Weekly News, October 23 to 29, 2023
Hi there GPCR minds! Join us for a deep dive into the world of GPCRs. GPCR Symposium for the year on GPCRs in Immunology and Oncology! Research ThermoBRET: A Ligand-Engagement Nanoscale Thermostability Assay Applied to GPCRs Reviews, GPCRs Pharmaceuticals Senior Director, In vitro pharmacology - Crinetics Pharmaceuticals In vivo Antibody Discovery Research GPCR Ecosystem
- Dr. GPCR University registration is now open! Secure your spot now!
neurotransmitter responses by G-protein regulators András D Tóth, Gábor Turu, and László Hunyady for their research Research Design, Synthesis, and Characterization of New δ Opioid Receptor-Selective Fluorescent Probes research position Senior or Lead Researcher Senior Scientist, Cryo-Electron Microscopy Postdoctoral Research Associate Senior Scientist - Discovery Biotherapeutics Join Dr. GPCR Ecosystem






