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This week, we have a comprehensive coverage of 12 GPCR research papers. Submit a few slides for a poster presentation to showcase your research and network with our community Target in Ovarian Cancer Methods & Updates in GPCR Research Alared: Solvatochromic and Fluorogenic Red I - Global Research Technologies Novo Nordisk Postdoctoral Associate Research Technologist I Senior Scientist- Internal Medicine Research Unit Postdoctoral Scholar – Synaptic physiology, optical imaging

Hi GPCR Fanatics,   This week’s insights will help you avoid wasted time, poor forecasts, and stalled 🔹 Elevate your strategy → Building clarity in GPCR drug discovery Even the strongest GPCR programs GPCR University Learner Dr. GPCR Podcast - Surviving Discovery’s Gauntlet Dr. Listen Now – Real Lessons from a GPCR Expert ➤ The future of GPCR isn’t waiting. GPCR Team Read Full Edition ➤

We have a total of 34 insightful GPCR research papers and seven updates from the industry. Stay informed and up to date with the latest GPCR research and industry news. Sara Marsango and Graeme Milligan for their research on the Regulation of the pro-inflammatory G protein-coupled signaling axes Methods & Updates in GPCR Research ONE-GO: Direct detection of context-dependent GPCR Research Technologist I Join Dr.

Katharina Grotsch, Bryan L Roth, Valery V Fokin  et al. for their research on Virtual Screening of a If you have any research you would like to showcase to our community, you can submit a poster presentation vertebrates Methods & Updates in GPCR Research Exploring GPCR conformational dynamics using single-molecule Senior Associate Scientist - Global Research Technologies Novo Nordisk Scientist I - Global Research , pharmacology Research Fellow Join Dr.

This week's highlight includes congrats to: David A Cooper, David Minh, et al., for their research on If you have any research you would like to showcase to our community, you can submit a poster presentation Research Technologies Novo Nordisk Scientist I - Global Research Technologies Novo Nordisk Postdoctoral Associate Research Technologist I Senior Scientist- Internal Medicine Research Unit Postdoctoral Scholar – Synaptic physiology, optical imaging, substance use disorder, pharmacology Research Fellow Postdoctoral

Hey there, GPCR Enthusiasts! Ready for your GPCR quest, so bold and bright? Take action immediately to join our esteemed learning community! to party with GPCRs next week! HIGHLIGHT Senior Scientist, GPCR Pharmacology Research Associate - Professor Graeme Milligan Postdoc Research High-throughput G protein-coupled receptor-based autocrine screening for secondary metabolite

resurgence in recent times for exploratory analyses to identify previously unknown regions critical to GPCR Additionally, deep mutational scanning can generate large-scale datasets, allowing researchers to determine In summary, mutagenesis can be a critical tool in drug discovery, particularly for studying GPCRs. The directed evolution of ligand specificity in a GPCR and the unequal contributions of efficacy and Molecular determinants of ligand efficacy and potency in GPCR signaling.

Miles Thompson, Alexander Hauser, Caroline Gorvin et al. for their research on GPCR gene variants and If you want to showcase your research, you can submit a poster presentation to our community, take advantage Research A multicolor suite for deciphering population coding of calcium and cAMP in vivo Cryo-EM advances World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs Postdoctoral Associate Research Technologist I Senior Scientist- Internal Medicine Research Unit Postdoctoral Scholar – Synaptic physiology, optical

August 2022 GPCRs steer G i and G s selectivity via TM5-TM6 switches as revealed by structures of serotonin The structural basis for G protein subtype selectivity by these GPCRs remains elusive. We find that the macro-switch by the TM5-TM6 length is shared by class A GPCR-G protein structures. by class A GPCRs and extend the basis of ligand recognition at serotonin receptors." Read more at the source #DrGPCR #GPCR #IndustryNews

Interested in showcasing your research? Submit a poster presentation to our community, seize networking opportunities, and elevate your profile Insights from Gαi3 research GPCRs in Cardiology, Endocrinology, and Taste The Prostaglandin E2 EP3 Receptor Methods & Updates in GPCR Research Direct interrogation of context-dependent GPCR activity with a universal World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Postdoctoral Associate Research

, multiplexed platform to investigate GPCR-RAMP biology  like never before. antibodies for hard-to-study receptors And most importantly, it’s free to academics , built for the community . ________________ Keyword Cloud : GPCR-RAMP interactions , Family B GPCRs , GPCR scientist network , GPCR data platform , Dr. GPCR ecosystem

research and drug discovery. This case study underscores the critical importance of mutagenesis in GPCR research. By pinpointing the molecular determinants of ligand efficacy and potency in GPCR signalling, this research While this case study highlights the essential role of mutagenesis in GPCR research, it is not the only Decoding GPCR Function: The Role of Mutagenesis in Rational Drug Discovery. Dr. GPCR Ecosystem; Dr.

September 2022 GPCR/endocytosis/ERK signaling/S2R is involved in the regulation of the internalization We investigated the influence of specific inhibitors of G protein-coupled receptors (GPCR), endocytosis The inhibitors of GPCR, ERK1/2, phagocytosis, and clathrin-mediated endocytosis (CME) as well as siRNA Overall, phagocytosis, CME, GPCR, ERK signaling, and S2R/TMEM97 are involved in the internalization of Read more at the source #DrGPCR #GPCR #IndustryNews

GPCR Summit 2022 is less than a month away! Come live and breathe GPCRs with us and don’t forget to submit your abstract. ➡️https://bit.ly/3Q7hlnT #gpcr #drgpcr

Watch Episode 167 Today’s GPCR scientists don’t want to study one interaction, they want to model the Compatible with multiple readouts: proximity, immuno assays, pulldowns Validated antibodies + digital search protein interactions  (e.g., 14-3-3) Heterodimerization Endogenous vs. overexpressed systems Orphan GPCR Listen to the complete episode to learn more. _________________ Keyword Cloud : GPCR scientist network , GPCR online course , GPCR data platform , multiplex assays , GPCR drug discovery

Get the latest updates on breakthroughs in GPCR research with our concise and comprehensive summaries Their research reveals how VU0486846 reduces neurogliosis in female Alzheimer's mice. Dr. in Oncology and Immunology Itaconate in host inflammation and defense Methods & Updates in GPCR Research World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Research Technologist I Senior Scientist- Internal Medicine Research Unit Postdoctoral Scholar – Synaptic physiology, optical imaging

Why Purpose Matters in Science For some researchers, science is a job. For others, it’s a calling. That alignment between curiosity and urgency set her on the path toward doctoral research. What’s Next in Her Opioid Research Catherine’s current experiments focus on outcomes such as respiratory And GPCR pharmacology isn’t just an academic pursuit—it’s essential to understanding and responding to Catherine’s story shows that when purpose drives research, science becomes more than a job—it becomes

If you want to share your work with our community, please don’t hesitate to fill out this form. You'll share your contributor articles with the community, stay updated with GPCR literature, join a and lipid second messenger signaling Methods & Updates in GPCR Research A bioluminescent and homogeneous Research Unit NEW Postdoctoral Scholar – Synaptic physiology, optical imaging, substance use disorder , pharmacology Research Fellow Postdoctoral Fellow – Molecular Pharmacology of Feeding Behavior Director

have a poster session in breakout rooms on Zoom; if you are interested in sharing your work with our community You'll share your contributor articles with the community, stay updated with GPCR literature, network involved in metabolic diseases: pharmacotherapeutic development updates Methods & Updates in GPCR Research The dark sides of the GPCR tree - research progress on understudied GPCRs Structural and Molecular Insights Scientist Post-Doc position Lead Researcher Join Dr.

have a poster session in breakout rooms on Zoom; if you are interested in sharing your work with our community You'll share your contributor articles with the community, stay updated with GPCR literature, join a in GPCR Pharmacology: Unraveling the Secrets of Cellular Communication Bowes Biomedical Investigator Takes Aim at Cracking Cellular Communication Code Aelis Farma will be at Bio Europe Spring in Barcelona World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Research Fellow NEW  Postdoctoral

GPCR Podcast, we have Dr. Pina Cardarelli, CSO of GPCR Therapeutics. ecosystem.drgpcr.com/dr-gpcr-podcast/ #gpcr#drgpcr #podcast

October 2022 "G protein-coupled receptors (GPCRs) play critical roles in human physiology and are one endogenous ligands (orthosteric site), allosteric modulators offer new avenues for the regulation of GPCR Recent advances in the structure determination of GPCRs bound to different types of allosteric modulators In this review, we provide a systematic analysis of the currently available GPCR structures in complex Read more at the source #DrGPCR #GPCR #IndustryNews

Among the different families of G-protein-coupled receptors (GPCRs), adhesion GPCRs (aGPCRs) represent Fortunately, the scientific community has become increasingly interested in studying these proteins and supporting the encrypted ligand hypothesis that was put forward by the community before these structures knowing the factors that determine the selectivity of coupling represents a very interesting area of research and open new perspectives for the community to formulate strategies to help modulate the activation

Please email us at Hello@DrGPCR.com if you want to share your work with our community. We’ll send your contributor articles to our community, keep you updated with GPCR papers, receive support Hemicyanine as a "Turn-On" Fluorescence Probe Industry News Domain Therapeutics awarded Hospital-University Research World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs Post-Doc position Lead Researcher Senior Researcher in Structural Biology Post-Doctoral Fellow Postdoctoral Fellow Research Laboratory Specialist

15 insightful research papers and industry updates. Stay informed with the most recent developments in GPCR research and industry news. Join the global GPCR community to present your research—submit your abstract using this form. Research ORP9-PH domain-based fluorescent reporters for visualizing phosphatidylinositol 4-phosphate pharmacology Senior Scientist - Receptor Pharmacology Postdoctoral Scientist Senior Research Associate

Take a moment to browse our latest coverage of GPCRs this week, featuring 24 insightful research papers Stay informed with the most recent developments in GPCR research and industry news. Join the global GPCR community to share your research—submit your abstract using this form. Research Engineering G protein-coupled receptors for stabilization Cryo-electron microscopy for GPCR research and drug discovery in endocrinology and metabolism Chemogenetic Signaling in Space and Time

one GPCR Event, and two GPCR job ads! Research G-Protein Coupled Receptor Gpr-1 Is Important for the Growth and Nutritional Metabolism of Jude Children’s Research Hospital adds $13 million project to Research Collaboratives Program AIRSUPRA World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Post-Doc position NEW Lead Researcher Senior Researcher in Structural Biology Post-Doctoral Fellow Postdoctoral Fellow Research Laboratory

The newest GPCR research is hot off the press! G protein-coupled receptor Methods & Updates in GPCR Research RediscMol: Benchmarking Molecular Generation Morgan Healthcare Conference Isomorphic Labs Announces Strategic Multi-Target Research Collaboration With Novartis Salipro Biotech announces multi-target research collaboration with an additional Top5 crop World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Postdoctoral Fellow NEW Research

Their method allows researchers to explore different linker positions, tailor activity (agonist or antagonist GPCR ecosystem , Celtarys is opening up that model to the broader research community. The goal? . _______________ Keyword Cloud:   GPCR data platform , fluorescent ligands , assay development , GPCR research community , Dr. GPCR ecosystem , GPCR webinar series

Temperature optimization and application to cell-based kinetic studies "G protein-coupled receptors (GPCRs ) are an important receptor superfamily and common therapeutic targets. In this regard, luminescence-based biosensors have revolutionized our ability to monitor GPCR signaling The GloSensor™ cAMP assay enables real-time monitoring of signaling downstream of many GPCRs. for drug discovery" Read more at the source #DrGPCR #GPCR #IndustryNews