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- Are You Guessing or Forecasting? Master GPCR Pharmacologic Models Before It’s Too Late
Hi GPCR Fanatics, This week’s insights will help you avoid wasted time, poor forecasts, and stalled 🔹 Elevate your strategy → Building clarity in GPCR drug discovery Even the strongest GPCR programs GPCR University Learner Dr. GPCR Podcast - Surviving Discovery’s Gauntlet Dr. Listen Now – Real Lessons from a GPCR Expert ➤ The future of GPCR isn’t waiting. GPCR Team Read Full Edition ➤
- 📰 GPCR Weekly News, March 18 to 24, 2024
Miles Thompson, Alexander Hauser, Caroline Gorvin et al. for their research on GPCR gene variants and If you want to showcase your research, you can submit a poster presentation to our community, take advantage Research A multicolor suite for deciphering population coding of calcium and cAMP in vivo Cryo-EM advances World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs Postdoctoral Associate Research Technologist I Senior Scientist- Internal Medicine Research Unit Postdoctoral Scholar – Synaptic physiology, optical
- Discover the Hottest GPCR News of the Week: Oct 7-13, 2024!
Hey there, GPCR Enthusiasts! Ready for your GPCR quest, so bold and bright? Take action immediately to join our esteemed learning community! to party with GPCRs next week! HIGHLIGHT Senior Scientist, GPCR Pharmacology Research Associate - Professor Graeme Milligan Postdoc Research High-throughput G protein-coupled receptor-based autocrine screening for secondary metabolite
- 📰 GPCR Weekly News, March 11 to 17, 2024
Interested in showcasing your research? Submit a poster presentation to our community, seize networking opportunities, and elevate your profile Insights from Gαi3 research GPCRs in Cardiology, Endocrinology, and Taste The Prostaglandin E2 EP3 Receptor Methods & Updates in GPCR Research Direct interrogation of context-dependent GPCR activity with a universal World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Postdoctoral Associate Research
- Decoding GPCR Function: The Role of Mutagenesis in Rational Drug Discovery
resurgence in recent times for exploratory analyses to identify previously unknown regions critical to GPCR Additionally, deep mutational scanning can generate large-scale datasets, allowing researchers to determine In summary, mutagenesis can be a critical tool in drug discovery, particularly for studying GPCRs. The directed evolution of ligand specificity in a GPCR and the unequal contributions of efficacy and Molecular determinants of ligand efficacy and potency in GPCR signaling.
- Purpose-Driven Opioid Research: Catherine Demery’s Academic Path
Why Purpose Matters in Science For some researchers, science is a job. For others, it’s a calling. That alignment between curiosity and urgency set her on the path toward doctoral research. What’s Next in Her Opioid Research Catherine’s current experiments focus on outcomes such as respiratory And GPCR pharmacology isn’t just an academic pursuit—it’s essential to understanding and responding to Catherine’s story shows that when purpose drives research, science becomes more than a job—it becomes
- Targeted Drug Design through GPCR Mutagenesis: Insights from β2AR
research and drug discovery. This case study underscores the critical importance of mutagenesis in GPCR research. By pinpointing the molecular determinants of ligand efficacy and potency in GPCR signalling, this research While this case study highlights the essential role of mutagenesis in GPCR research, it is not the only Decoding GPCR Function: The Role of Mutagenesis in Rational Drug Discovery. Dr. GPCR Ecosystem; Dr.
- From One to Many: How a GPCR Curiosity Became a Field-Wide Toolkit
, multiplexed platform to investigate GPCR-RAMP biology like never before. antibodies for hard-to-study receptors And most importantly, it’s free to academics , built for the community . ________________ Keyword Cloud : GPCR-RAMP interactions , Family B GPCRs , GPCR scientist network , GPCR data platform , Dr. GPCR ecosystem
- 📰 GPCR Weekly News, March 4 to 10, 2024
Get the latest updates on breakthroughs in GPCR research with our concise and comprehensive summaries Their research reveals how VU0486846 reduces neurogliosis in female Alzheimer's mice. Dr. in Oncology and Immunology Itaconate in host inflammation and defense Methods & Updates in GPCR Research World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Research Technologist I Senior Scientist- Internal Medicine Research Unit Postdoctoral Scholar – Synaptic physiology, optical imaging
- Dr. Josephine (Pina) Cardarelli - Dr. GPCR Podcast
GPCR Podcast, we have Dr. Pina Cardarelli, CSO of GPCR Therapeutics. ecosystem.drgpcr.com/dr-gpcr-podcast/ #gpcr#drgpcr #podcast
- Allosteric modulation of GPCRs: From structural insights to in silico drug discovery
October 2022 "G protein-coupled receptors (GPCRs) play critical roles in human physiology and are one endogenous ligands (orthosteric site), allosteric modulators offer new avenues for the regulation of GPCR Recent advances in the structure determination of GPCRs bound to different types of allosteric modulators In this review, we provide a systematic analysis of the currently available GPCR structures in complex Read more at the source #DrGPCR #GPCR #IndustryNews
- Luciferase-based GloSensor™ cAMP assay: Temperature optimization and application to cell-based kinet
Temperature optimization and application to cell-based kinetic studies "G protein-coupled receptors (GPCRs ) are an important receptor superfamily and common therapeutic targets. In this regard, luminescence-based biosensors have revolutionized our ability to monitor GPCR signaling The GloSensor™ cAMP assay enables real-time monitoring of signaling downstream of many GPCRs. for drug discovery" Read more at the source #DrGPCR #GPCR #IndustryNews
- 📰 GPCR Weekly News, February 19 to 25, 2024
If you want to share your work with our community, please don’t hesitate to fill out this form. You'll share your contributor articles with the community, stay updated with GPCR literature, join a and lipid second messenger signaling Methods & Updates in GPCR Research A bioluminescent and homogeneous Research Unit NEW Postdoctoral Scholar – Synaptic physiology, optical imaging, substance use disorder , pharmacology Research Fellow Postdoctoral Fellow – Molecular Pharmacology of Feeding Behavior Director
- From Multiplex to Models: Scaling Up GPCR Discovery in the Post-Silo Era
Watch Episode 167 Today’s GPCR scientists don’t want to study one interaction, they want to model the Compatible with multiple readouts: proximity, immuno assays, pulldowns Validated antibodies + digital search protein interactions (e.g., 14-3-3) Heterodimerization Endogenous vs. overexpressed systems Orphan GPCR Listen to the complete episode to learn more. _________________ Keyword Cloud : GPCR scientist network , GPCR online course , GPCR data platform , multiplex assays , GPCR drug discovery
- 📰 GPCR Weekly News, February 5 to 11, 2024
have a poster session in breakout rooms on Zoom; if you are interested in sharing your work with our community You'll share your contributor articles with the community, stay updated with GPCR literature, network involved in metabolic diseases: pharmacotherapeutic development updates Methods & Updates in GPCR Research The dark sides of the GPCR tree - research progress on understudied GPCRs Structural and Molecular Insights Scientist Post-Doc position Lead Researcher Join Dr.
- Overview of adhesion GPCRs self-activation
Among the different families of G-protein-coupled receptors (GPCRs), adhesion GPCRs (aGPCRs) represent Fortunately, the scientific community has become increasingly interested in studying these proteins and supporting the encrypted ligand hypothesis that was put forward by the community before these structures knowing the factors that determine the selectivity of coupling represents a very interesting area of research and open new perspectives for the community to formulate strategies to help modulate the activation
- 📰 GPCR Weekly News, February 12 to 18, 2024
have a poster session in breakout rooms on Zoom; if you are interested in sharing your work with our community You'll share your contributor articles with the community, stay updated with GPCR literature, join a in GPCR Pharmacology: Unraveling the Secrets of Cellular Communication Bowes Biomedical Investigator Takes Aim at Cracking Cellular Communication Code Aelis Farma will be at Bio Europe Spring in Barcelona World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Research Fellow NEW Postdoctoral
- Beyond the Probe: Scaling Innovation From the Bench to Product Launch
Their method allows researchers to explore different linker positions, tailor activity (agonist or antagonist GPCR ecosystem , Celtarys is opening up that model to the broader research community. The goal? . _______________ Keyword Cloud: GPCR data platform , fluorescent ligands , assay development , GPCR research community , Dr. GPCR ecosystem , GPCR webinar series
- 📰 GPCR Weekly News, January 22 to 28, 2024
Please email us at Hello@DrGPCR.com if you want to share your work with our community. We’ll send your contributor articles to our community, keep you updated with GPCR papers, receive support Hemicyanine as a "Turn-On" Fluorescence Probe Industry News Domain Therapeutics awarded Hospital-University Research World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs Post-Doc position Lead Researcher Senior Researcher in Structural Biology Post-Doctoral Fellow Postdoctoral Fellow Research Laboratory Specialist
- Residency time of agonists does not affect the stability of GPCR-arrestin complexes
September 2022 "Background and purpose: The interaction of arrestins with G-protein coupled receptors (GPCRs GPCRs that internalize without arrestin have been classified as "class A" GPCRs whereas "class B" GPCRs The interaction of arrestins with GPCRs requires both agonist activation and receptor phosphorylation Read more at the source #DrGPCR #GPCR #IndustryNews
- 📰 GPCR Weekly News, June 3 to June 9, 2024
15 insightful research papers and industry updates. Stay informed with the most recent developments in GPCR research and industry news. Join the global GPCR community to present your research—submit your abstract using this form. Research ORP9-PH domain-based fluorescent reporters for visualizing phosphatidylinositol 4-phosphate pharmacology Senior Scientist - Receptor Pharmacology Postdoctoral Scientist Senior Research Associate
- 📰 GPCR Weekly News, January 15 to 21, 2024
one GPCR Event, and two GPCR job ads! Research G-Protein Coupled Receptor Gpr-1 Is Important for the Growth and Nutritional Metabolism of Jude Children’s Research Hospital adds $13 million project to Research Collaboratives Program AIRSUPRA World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Post-Doc position NEW Lead Researcher Senior Researcher in Structural Biology Post-Doctoral Fellow Postdoctoral Fellow Research Laboratory
- 📰 GPCR Weekly News, May 27 to June 2, 2024
Take a moment to browse our latest coverage of GPCRs this week, featuring 24 insightful research papers Stay informed with the most recent developments in GPCR research and industry news. Join the global GPCR community to share your research—submit your abstract using this form. Research Engineering G protein-coupled receptors for stabilization Cryo-electron microscopy for GPCR research and drug discovery in endocrinology and metabolism Chemogenetic Signaling in Space and Time
- 📰 GPCR Weekly News, January 1 to 7, 2024
The newest GPCR research is hot off the press! G protein-coupled receptor Methods & Updates in GPCR Research RediscMol: Benchmarking Molecular Generation Morgan Healthcare Conference Isomorphic Labs Announces Strategic Multi-Target Research Collaboration With Novartis Salipro Biotech announces multi-target research collaboration with an additional Top5 crop World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Postdoctoral Fellow NEW Research
- Identification of GPCRs Modulating Flow-induced Signaling Pathways in Vascular Endothelial Cells
Brian Arey is doing. https://www.ecosystem.drgpcr.com/dr-gpcr-virtual-cafe/ #gpcr #drgpcr #virtualcafe
- 📰 GPCR Weekly News, January 8 to 14, 2024
We’ve curated 10 GPCR papers, seven industry news, and two GPCR job ads! This week's highlight: Dr. : Empowering the ML Community in Molecular Predictive Modelling NanoImaging Services Appoints John Rigg World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Senior Researcher in Structural Biology NEW Post-Doctoral Fellow Postdoctoral Fellow Research Laboratory Specialist Associate Postdoctoral GPCR Ecosystem
- Statin-induced increase in actin polymerization modulates GPCR dynamics and compartmentalization
regulating the dynamics of the serotonin1A receptor, a crucial neurotransmitter G protein-coupled receptor (GPCR in understanding the modulatory role of the membrane environment on the organization and dynamics of GPCRs Read more at the source #DrGPCR #GPCR #IndustryNews
- 📰 GPCR Weekly News, December 18 to 31, 2023
GPCR Access to Dr. Research Direct Binding Methods to Measure Receptor-Ligand Interactions How accurately can one predict Investigator, In Vitro Biology NEW Associate Scientist Postdoctoral Scholar - O’Neill Lab Junior Research Scientist Postdoctoral Fellow Post-Doc Research Associate Assistant/Associate Professor Explore Dr. GPCR Ecosystem
- 📰 GPCR Weekly News, December 11 to 17, 2023
The latest and greatest in GPCR research is here, this week we’ve curated 14 GPCR papers, 7 industry Ross Cheloha's research involves semi-synthetic nanobody-ligand conjugates with enhanced transcriptional Research Phosphorylation Sites of the Gastric Inhibitory Polypeptide Receptor (GIPR) Revealed by Trapped-Ion-Mobility Lab NEW Junior Research Scientist Postdoctoral Fellow Post-Doc Research Associate Assistant/Associate GPCR Ecosystem
- 📰 GPCR Weekly News, December 4 to 10, 2023
Hi GPCR lovers! in Neuroscience Research progress on the role of orphan receptor GPR139 in neuropsychiatric behaviours Research Transcriptome analysis of Schizothorax oconnori (Cypriniformes: Cyprinidae) oocytes: The role Research Associate NEW Assistant/Associate Professor Principal scientist – oncology biomarker expert Postdoctoral Fellow Scientific Assistant Scientist Lead Researcher Explore Dr.










