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- Orthosteric Binding Experiments: How to Avoid the Most Common Data Pitfalls
In this session, you’ll gain: Why saturation and displacement assays fail when protein stoichiometry
- Chemokine receptor-targeted drug discovery: progress and challenges
inappropriate target selection and insufficient dosing of chemokine receptor antagonists in vivo might be the main
- GPCR Pharmacology Insights That Prevent Real Drug Discovery Failures
In this session, you’ll gain: How system sensitivity transforms potency, efficacy, and agonist classification
- From Failed Experiments to Predictive GPCR Models
His introduction came through a practical suggestion: explore a new protein family that was gaining traction
- Targeting Intracellular Allosteric Sites in GPCRs
Allosteric modulation is gaining prominence in GPCR therapeutics, with the discovery of an intracellular
- High-Content Screening for GPCR Programs: Overcoming Assay Limitations with Fluorescent Ligands
Non-Radioactive Workflow By removing isotopes, researchers gain safer, more scalable, and more environmentally
- Odorant receptors – a bit of smell for drug discovery
In the cardiovascular system, ORs have the potential to operate as the main carriers of endogenously
- Artificial intelligence – faster, smarter, cheaper GPCR drug discovery
The future According to the authors, the future of AI relies in 6 main areas: 1.




