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Slosky LM, Caron MG, Barak LS. Biased Allosteric Modulators: New Frontiers in GPCR Drug Discovery.

. 👉 Learn more about CELT-311 References Booij TH, Price LS, Danen EHJ. 3D Cell-Based Assays for Drug

August 2022 "Psychedelic research across different disciplines and biological levels is growing at a remarkably fast pace. In the prospect of a psychedelic drug becoming again an approved treatment, much of these efforts have been oriented toward exploring the relationship between the actual psychedelic effects and those manifestations of therapeutic interest. Considering the central role of the serotonin 5-HT2A receptor in the distinct effects of psychedelics in human psyche, neuropharmacology sits at the center of this debate and exploratory continuum. Here we discuss some of the most recent findings in human studies and contextualize them considering previous preclinical models studying phenomena related to synaptic plasticity. A special emphasis is placed on knowledge gaps, challenges, and limitations to evaluate the underpinnings of psychedelics' potential antidepressant action." Read more at the source #DrGPCR #GPCR #IndustryNews

into KSHV-GPCR constitutive activation and CXCL1 chemokine recognition Structural basis of psychedelic LSD

Of 161 molecules tested, 42 substituted more than 50% of [³H]-LSD at 10 μM, achieving a 26% hit rate.

Axelrod Symposium: Plant-derived molecules acting on GPCRs Molecular characterization of recombinant LSDV

Perspective on Class C GPCR Based Genetically Encoded Biosensors Emergence of lumpy skin disease virus (LSDV

genome: Pathways to progress Industry News Anatole Klepatsky, Orion's COO, Shared Innovative Insights at LSBC

Hypertension Treatment from KBP Biosciences Exscientia to Present New Preclinical Data for AI-designed LSD1

Industry News Orion Biotechnology will be participating in a panel discussion at the LSX World Congress

This class of psychoactive substances, which includes lysergic acid diethylamide (LSD), psilocybin, mescaline

understanding and translational potential of psychedelic drugs such as lysergic acid diethylamide (LSD

Protein-Coupled Receptors (GPCRs), today announced that it will be presenting important new data at both LSX