Search Results
Results found for "Heidi E. Hamm"
- Novel interaction between neurotrophic factor-α1/carboxypeptidase E and serotonin receptor, 5-HTR1E,
neuroprotective mechanism involving interaction between neurotrophic factor-α1 (NF-α1/carboxypeptidase E,
- A robust and Efficient FRET-Based Assay for Cannabinoid Receptor Ligands Discovery.
E. S.; Vahlberg, T.; Lahdenpohja, S.; Rinne, J. O.; Brück, A. E. E. .; Zirwes, E. .; Trinquet, E.; Pin, J.-P. E.
- Applications of Fluorescent Probes in Confocal Imaging of GPCRs: From Live to Fixed Cells
Nov 8; 13:RP97033. doi: 10.7554/eLife.97033.3 Maurel D, Comps-Agrar L, Brock C, Rives ML, Bourrier E, Ayoub MA, Bazin H, Tinel N, Durroux T, Prézeau L, Trinquet E, Pin JP. Navarro G, Sotelo E, Raïch I, Loza MI, Brea J, Majellaro M.
- Canonical chemokine receptors as scavenging “decoys”
E, 2002). E., et al. 2008). E., et al. 2008).
- From DNA day to GPCR genomics
D., Rands, E., Diehl, R. E., Mumford, R. A., Slater, E. E., Sigal, I. S., Caron, M.
- Optimizing HTRF Assays with Fluorescent Ligands: Time-Resolved Fluorescence in GPCR Research
Source: Navarro G, Sotelo E, Raïch I, Loza MI, Brea J, Majellaro M. References Navarro G, Sotelo E, Raïch I, Loza MI, Brea J, Majellaro M. Degorce F, Card A, Soh S, Trinquet E, Knapik GP, Xie B.
- Nanobodies: New Dimensions in GPCR Signaling Research
J., Pardon, E., Casarosa, P., Chae, P. S., Devree, B. T., Rosenbaum, D. M., Thian, F. M., Manglik, A., Hu, J., Hu, K., Eitel, K., Hübner, H., Pardon, E., Valant, C., Sexton, P. M., Dukkipati, A., Feinberg, E. N., Angelini, A., Waghray, D., Dror, R. O., Ploegh, H. D., Tworak, A., Watanabe, K., Pardon, E., Steyaert, J., Kandori, H., Katayama, K., Kiser, P.
- Dr. GPCR Virtual Cafe with Matthew Eddy - New date!
Matthew E. on Friday, October 7th at 1 PM ET.
- Decoding β-Arrestins: from Structure to function
GPCR phosphorylation patterns, which influence their conformational states and functions (Matthees, E. E. et al. 2022). E. et al. 2017). evolutionary conservation of both isoforms from fish to mammals indicates their non-redundant roles (Gurevich, E. determining the formation of protein complexes and their functions within specific tissues (Matthees, E.
- Opioid Ligands Addressing Unconventional Binding Sites and More Than One Opioid Receptor Subtype
That is, besides classical ligands, a great number of bivalent ligands (i. e. aiming on two distinct
- Advantages of Fluorescent Probes in GPCR Assays
References Barbazán J, Majellaro M, Martínez AL, Brea JM, Sotelo E, Abal M. Sridharan R, Zuber J, Connelly SM, Mathew E, Dumont ME.
- Decoding GPCR Function: The Role of Mutagenesis in Rational Drug Discovery
E., Vitale, R. M., Tomašević, N., ... & Carreira, E. M. (2024).
- 🤯Mind-blowing GPCR Scoops! Discover the Latest Breakthroughs! ⦿ Nov 18 - 24, 2024
Ziaurrehman Tanoli , Saad Hassan , Umut Onur Özcan , Jimmy Caroli , Albert J Kooistra , David E Herrera , Søren N Andreassen , Jimmy Caroli , Albert J Kooistra , Gáspár Pándy-Szekeres , David E
- An overview of the compartmentalized GPCR Signaling: Relevance and Implications
E., & Puthenveedu, M. A. (2021). Compartmentalized GPCR Signaling from Intracellular Membranes. E., Healy, M. D., & Collins, B. M. (2019). E., French, R. P., Lowy, A. M., & Murray, F. (2018).
- Discover the Hottest GPCR News of the Week: Oct 7-13, 2024!
along the murine gastrointestinal tract Intracellular TAS2Rs act as a gatekeeper for the excretion of harmful molecular dynamics simulations Leukotriene B4 receptor 1 (BLT1) activation by leukotriene B4 (LTB4) and E
- Successful prednisolone or calcimimetic treatment of acquired hypocalciuric hypercalcemia caused...
showed spontaneously fluctuating Ca levels from approximately normal to near fatally high ranges, (e)
- Harnessing Deep Mutational Scanning for Enhanced Drug Discovery
tailored to the genetic makeup of individual patients, enhancing therapeutic outcomes and minimising harm B., Mehrotra, E., Patrick Rockefeller Grimes, Zahm, A. M., Trinidad, D. D., English, J.
- Feeder or trigger – CCR2 as a scavenger and regulator of cell migration
E. Cardona et al. 2008). E. Cardona et al. 2008).
- Fluorescence Polarization in GPCR Research
Gioé-Gallo C, Mallo-Abreu A, Brea J, Loza MI, García-Rey A, García-Mera X, Gutiérrez-de-Terán H, Sotelo E.
- Targeted Drug Design through GPCR Mutagenesis: Insights from β2AR
B., Mehrota, E., Grimes, P. R., ... & Manglik, A. (2024).
- Targeting GPCRs in the CNS: Advances in Drug Discovery Strategies
Curr Issues Mol Biol. 2024 Oct 19;46(10):11646-11664. doi: 10.3390/cimb46100691 Navarro G, Sotelo E,
- Dr. GPCR University registration is now open! Secure your spot now!
This week's highlight includes congrats to: Clementine E Philibert and Mikel Garcia-Marcos for their
- GPCR News Flash! Top Updates You Can't-Miss! + University CheatSheet is finally available! ❄ Dec 2 - 8, 2024
Structure-guided design of a peripherally restricted chemogenetic system Hye Jin Kang , Brian E Krumm
- 📰 GPCR Weekly News, November 13 to 19, 2023
Encoded Fluorescent Indicators Design of an effective small expression tag to enhance GPCR production in E.
- Illuminating GPCR Research: FRET and BRET-Based Sensors Shed Light on Cellular Signaling
Goyet, E., et al., Fast and high resolution single-cell BRET imaging.
- Unlocking Cell's Secrets: Spontaneous β-Arrestin-Membrane Preassociation Drives Receptor-Activation
Reiter, E., Ahn, S., Shukla, A.K., and Lefkowitz, R.J. (2012).
- Melatonin MT 2 receptor is expressed and potentiates contraction in human airway smooth muscle
receptor in native human and guinea pig airway smooth muscle and cultured human airway smooth muscle (HASM MT1/MT2 agonist ramelteon (10 µM) significantly inhibited forskolin-stimulated cAMP accumulation in HASM potentiated acetylcholine-stimulated [Ca2+]i increases, stress fiber formation through the MT2 receptor in HASM
- Glyco-sulfo hotspots in the chemokine receptor system
affects the recognition of CCL21 but not CCL19, interfering with dendritic cell trafficking (Kiermaier E
- The Perils and Guardrails of Modifying Signalling Proteins in Bioassays
Wodak SJ, Paci E, Dokholyan NV, Berezovsky IN, Horovitz A, Li J, et al. Pearce A, Redfern-Nichols T, Wills E, Rosa M, Manulak I, Sisk C, et al.
