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Jianming Han, Tao Che for their analysis of GPCR-G protein selectivity revealed by structural pharmacology

GPCR-BSD: a database of binding sites of human G-protein coupled receptors under diverse states Fan Liu , Han

antagonist ([5P7]CCL5), and a small-molecule inverse agonist (maraviroc) (Tan, Zhu et al. 2013, Zheng, Han its constitutive activity (Yen, Schafer et al. 2022) which is also supported by mutagenesis studies (Han

Jiang, L.I., et al., Use of a cAMP BRET sensor to characterize a novel regulation of cAMP by the sphingosine

.; Han, G. W.; Wu, Y.; Zhao, S.; Shui, W.; Li, S.; Korde, A.; Laprairie, R. B.; Stahl, E. L.; Ho, J. -H.; Zvonok, N.; Zhou, H.; Kufareva, I.; Wu, B.; Zhao, Q.; Hanson, M. A.; Bohn, L. -H.; Wu, Y.; Wu, L.; Popov, P.; Benchama, O.; Zvonok, N.; Locke, K.; Qu, L.; Han, G. W.; Iyer, M.

Plate Layout and Sample Handling Automated liquid handlers and randomized plate layouts are used to minimize

It does not go away with more meetings, louder all-hands sessions, or rewritten pitch decks. 👉 It only

adaptations underscore Schild’s resilience—it remains one of the few analytical frameworks flexible enough to handle

Just her, radioactive ligands, and steady hands. Technique to Strategy Michelle reflects on how early-career researchers once prided themselves on “perfect hands What started as hand-built assays on ice has become integrated platforms for drug discovery, systems

researchers who use them , empowering scientists to move their work forward with the right resources in hand

There’s no central committee handing down orders. Grassroots science drives the agenda.”

Pharmacology, on the other hand, is often outsourced through collaborations with expert labs who specialize

Rethinking PK/PD Relationships With classical reversible drugs, effect and exposure walk hand in hand

FDA Focus No enzyme class is more important—or more unpredictable—than cytochrome P450s .CYP3A4 alone handles

Hearing Terry speak is more than an academic experience — it’s like being handed a new set of tools to

Launching Blue was Ajay’s first hands-on experience with biotech entrepreneurship.

t-test, ANOVA, F-test selection to power analysis  that prevents underpowered studies, this module hands

On the other hand, in fixed cells studies, it facilitates the structural context necessary to map receptor

On the other hand, when the polarized light hits the bound fluorescent ligand, the slower rotation speed

On the other hand, fluorescent ligands have a superior safety and environmental profile. They are easier to handle and store, which also lowers outsourcing.  

Handling of radioligands must be done by trained users in specific facilities and using specific equipment On the other hand, fluorescence signals can be easily monitored through confocal microscopy, plate readers Ease of handling is the other key difference, because fluorescent compounds do not require regulatory

.; Hanada, K.; Pagano, R. E.; Miller, L. J.

on-demand lessons , each featuring:   A short, focused video A concise written summary with key takeaways Handpicked

Surely more hands will move the needle.

Alessandro admits he struggled at first with handing over parts of his projects, fearing mistakes.

Start with our GPCR training program and get hands-on with virtual tools shaping the future of drug discovery

Collaborative Partnership:  I embed, contribute, and build solutions hand-in-hand with your team.

they need clarity ✅ Yamina’s Corner helps teams move from data chaos to decisive action ✅ This is hands-on

pursued experiments that were scientifically sound and directly publishable, a skill honed from years of hands-on

DiMasi JA, Grabowski HG, Hansen RW.