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Nicola Smith, Molecular Pharmacologist, lab head, and senior lecturer at UNSW Sydney.

Genome-wide identification of 216 G protein-coupled receptor (GPCR) genes from the marine water flea Here, we identified a total 216 full-length GPCR genes in the marine water flea Diaphanosoma celebensis

We have carried out MARTINI coarse-grained molecular dynamics simulations of SMO in POPC and in ciliary

The 1994 Nobel Prize in Physiology or Medicine was awarded to Alfred Goodman Gilman and Martin Rodbell Martin Rodbell – Facts - NobelPrize.org. https://www.nobelprize.org/prizes/medicine/1994/rodbell/facts Martin Rodbell – Nobel Lecture - NobelPrize.org. https://www.nobelprize.org/prizes/medicine/1994/rodbell

the engagement of the receptor with a certain effector, thus enriching a specific signaling pathway (Smith In fact, the requirements in terms of safety margin, oral bioavailability, and frequency of administration

For drug discovery teams navigating safety margins, biased signaling, and combination therapy design, Recognizing how your ligand interacts with the receptor lets you predict safety margins, dose–response

contributes to inflammatory joint pain Luke A Pattison , Rebecca H Rickman , Graham Ladds , Ewan St John Smith

Extracellular signal-regulated kinases – a potential pathway for GPCR-targeted drug discovery Nicola J Smith

Nichola J Smith's investigation: Gene expression of TAS1R taste receptors for cardiometabolic disease

.; Martin, B. R.; Abood, M. E. J Pharmacol Exp Ther   1996 , 278 (3), 989–999. (12)      Martín-Fontecha, M.; Angelina, A.; Rückert , B.; Rueda-Zubiaurre, A.; Martín-Cruz, L.; Van De Veen, W.; Akdis, M.; Ortega-Gutiérrez, S.; López-Rodríguez

This week's highlight includes congrats to: Junyi Liang, Niña Caculitan, and Adam W Smith for their research

acceptor is sufficient for a transmission of energy to occur between the Tb and fluorophore, which will emit

One of the atoms in the original molecule is replaced by a radionuclide, which emits radiation.

Elucidation, and Biological Activity of the Selective TACR2 Antagonist Tumonolide and its Aldehyde from a Marine disordered C-terminal domains Industry News Novartis continues to deliver strong sales growth and core margin

By measuring the way these cells scatter light and emit fluorescence, they can be identified, quantified

previously established chemical space, limiting their ability to identify truly novel chemotypes”(Thomas, Smith

This can be fixed by using fluorescent dyes that emit at longer wavelengths, where fluorescence from