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- Targeted Activation of G-Protein Coupled Receptor-Mediated Ca 2+ Signaling Drives Enhanced Cartilage
Control of chondrocyte/chondroprogenitor Ca2+ signaling has been attempted through mechanical and/or pharmacological
- Optimizing HTRF Assays with Fluorescent Ligands: Time-Resolved Fluorescence in GPCR Research
FRET-based technologies by providing high-performance fluorescent ligands designed specifically for pharmacological
- GPCR Collaboration: From Models to Medicine
GPCRs demanded something different: the integration of modeling, medicinal chemistry, and pharmacology Pharmacologists know they aren’t being oversold. A pharmacologist who understands docking, or a modeler who knows assay constraints, will collaborate
- Beyond Clearance: The Strategic Power of Irreversible Drug Binding
In this lesson, you'll gain: ✅ Clarity on what “irreversible” really means in kinetic and pharmacologic
- Extracellular signal-regulated kinases – a potential pathway for GPCR-targeted drug discovery
Pharmacological Reviews, 71(2), 267-315. Lu, N., & Malemud, C. J. (2019).
- Decoding GPCR Function: The Role of Mutagenesis in Rational Drug Discovery
Molecular Pharmacology , 90 (6), 703-714.
- 📰 GPCR Weekly News, September 25 to October 1, 2023
GTPase components to potentiate bacterial survival in Dictyostelium Reviews, GPCRs, and more Network pharmacology Cytokines GPCR Jobs NEW In vivo Antibody Discovery Research Scientist NEW In Vitro Biologist/Molecular Pharmacologist
- 📰 GPCR Weekly News, September 18 to 24, 2023
Technician II - Surgery Post-Doc Research Associate Research Technician Senior Research Associate, In Vitro Pharmacology
- 📰 GPCR Weekly News, September 11 to 17, 2023
Surgery NEW Post-Doc Research Associate NEW Research Technician Senior Research Associate, In Vitro Pharmacology
- 📰 GPCR Weekly News, September 4 to 10, 2023
Exhibition June 2 - 4, 2024 | Chemotactic Cytokines GPCR Jobs NEW Senior Research Associate, In Vitro Pharmacology
- Ode to GPCRs
Histamine pharmacology: from Sir Henry Dale to the 21st century. Br J Pharmacol 177, 469–489 (2020). https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14524/. ACS Pharmacol Transl Sci 3, 203–220 (2020). https://pubs.acs.org/doi/10.1021/acsptsci.0c00004/. 72. ACS Pharmacol Transl Sci 3, 221–236 (2020). https://pubs.acs.org/doi/full/10.1021/acsptsci.0c00006/.
- 📰 Breaking Down the Latest GPCR Discoveries: a Weekly Update (Nov 27-Dec 3, 2023)
, 2024 | 11th Adhesion GPCR Workshop July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology
- 📰 GPCR Weekly News, November 20 to 26, 2023
2024 | 9th GPCRs in Medicinal Chemistry July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology
- Chemokine receptor-targeted drug discovery: progress and challenges
existence as homo and herero-oligomeres at the cell surface should be considered when assessing the pharmacological
- Unlocking the Therapeutic Potential of Previously Undruggable GPCRs
chemical synthesis using Orion’s proprietary multiplex synthesis technology, and then screened for pharmacological in industry, and one that is uniquely capable of generating drug candidates with optimal molecular pharmacological Orion has world-renowned expertise in GPCR pharmacology and protein engineering, and its proprietary
- Adhesion GPCR Consortium Newsletter - May 2024
greatly impact not only the way we understand how aGPCR works but might also provide a guide to how pharmacological
- Overview of adhesion GPCRs self-activation
formulate strategies to help modulate the activation and signaling of these receptors, particularly with a pharmacological
- Unveiling GPCR Priming: The Hidden Synergy in Cellular Signalling
Mol Pharmacol, 2017. 91(5): p. 533-544.
- Artificial intelligence – faster, smarter, cheaper GPCR drug discovery
AI algorithms can integrate data from multiple sources, including genomics, proteomics, and pharmacological
- Decoding β-Arrestins: from Structure to function
Innovative structural biology techniques, pharmacological methods, state-of-the-art biosensors, supplementary
- Dr. Nicola J. Smith - Dr. GPCR Podcast
Nicola Smith, Molecular Pharmacologist, lab head, and senior lecturer at UNSW Sydney.







