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- The GPCR antibody signal that should have been there
then a turn to the research bench, and learned only there how unforgiving these reagents can be, in a lab A reagent that fails in someone’s lab, they argue, is more useful to hear about than one that quietly
- Knowing When to Walk, Knowing When to Run: Lessons from the Bench
Finding Your Place Ben shares the moment he realized he mattered, when he was the only one in the lab
- Fentanyl and Xylazine: Why Breathing Fails in Overdose
From Street Samples to Lab Models What makes Catherine’s research particularly powerful is how it stays connected to reality outside the lab. Why This Research Matters Beyond the Lab Catherine’s findings bridge the gap between basic receptor biology
- Beyond the Probe: Scaling Innovation From the Bench to Product Launch
Whether supporting CROs, academic labs, or pharma teams, Celtarys engages deeply with collaborators to
- From Multiplex to Models: Scaling Up GPCR Discovery in the Post-Silo Era
Building for the Future The Sakmar lab built a system to meet that need: Dual-epitope tagged constructs
- GPCR Selectivity Beyond the Receptor — Live April 9th with Bryan Roth
In this episode, Joseph Kim, a postdoctoral scholar in Ashish Manglik's lab at UCSF, discusses structural One small molecule studied in the Manglik lab interacts with both the ÎĽ- and Îş-opioid receptors, acting
- How Breakthroughs Happen: Eric Trinquet on Innovation, Serendipity & GPCRs
It’s a mindset shaped by decades in the lab—but it’s also a warning. smarter. 🚀 Why This Matters: Whether you’re launching a tool, starting a biotech, or running an academic lab—your
- Adhesion GPCR Consortium Newsletter - May 2024
For my postdoctoral training, I joined one of the labs that participated in Latrophilins’ discovery, the lab of Dr. asked if I was a student or a PI, I was more proud to say that I was coming as the founder of my own lab identifies extended synaptotagmin 1 as an intracellular interaction partner of GPR133 using proximity labeling PMID: 38758649 Member Simone Prömel’s lab shows that the nematode (C. elegans) homolog of CELSR, FMI-
- New Podcast, Sweet Structures & $2.2B GPCR Moves
Rock your favorite design, spark conversations in the lab, and help power everything we build—one mug
- đź“° GPCR Weekly News, July 17 to July 23, 2023
Robert Lefkowitz Lab NEW Postdoc Fellow - Dr. Robert Lefkowitz Lab Senior Research Specialist - Natural Sciences - Surgery Senior Scientist- Membrane Technologies Computational Protein Design (GPCR) Postdoctoral Fellow, Caron Lab Clinical Trial Associate
- A Note from Yamina: Building the Next Chapter of Dr. GPCR
Whether you’re an established expert or an early-career researcher, you and your lab will receive a complimentary goal of supporting the GPCR community while strengthening discovery where it truly happens — in the lab
- New Tools, Smart Signals, and The Kenakin Brief
Explore Terry's Corner From Chemistry Lab to GPCR Partner – New Podcast with Celtarys Dr.
- đź“° GPCR Weekly News, August 7 to 13, 2023
Channels, and Transport Proteins (March 24 - 29, 2024) GPCR Jobs NEW Postdoctoral Fellow NEW Research Laboratory Robert Lefkowitz Lab Postdoc Fellow - Dr. Robert Lefkowitz Lab Explore Dr. GPCR Ecosystem
- Dr. GPCR Spotlights Revvity’s pHSense™ Internalization Tools
Its GPCR research tools  support discovery teams and academic labs with precision reagents and validated
- Job Opportunity Spotlight #1: Principal Scientist, In Vitro Pharmacology
I keep an open door and you’ll find me among the team in the lab quite often.Â
- The Hidden Burn: How Internal Misalignment Drains Your Biotech’s Runway
Your lab is busy. Your timelines look full. But the wrong things are moving. If nothing changes after it, it was just a lab update.
- Ode to GPCRs
The 1994 Nobel Prize in Physiology or Medicine was awarded to Alfred Goodman Gilman and Martin Rodbell Gilman discovered that the transducer component of signal transduction that requires GTP is G-protein Gilman – Facts - NobelPrize.org. https://www.nobelprize.org/prizes/medicine/1994/gilman/facts/. 42. Gilman – Nobel Lecture - NobelPrize.org. https://www.nobelprize.org/prizes/medicine/1994/gilman/lecture
- Accelerating GPCR Drug Discovery
The assays are running, data is flowing in from your CROs or your internal labs , yet progress stalls
- đź“° GPCR Weekly News, September 25 to October 1, 2023
Matthew Eddy and lab research on GPCR signaling mechanisms using NMR spectroscopy with labeled receptors extracellular chloride ion Illuminating GPCR signaling mechanisms by NMR spectroscopy with stable-isotope labeled Appoints Eva-Lotta Allan as Chair of its Board of Directors Novo Nordisk and Evotec collaborate to launch LAB
- đź“° GPCR Weekly News, January 1 to 7, 2024
Morgan Healthcare Conference Isomorphic Labs Announces Strategic Multi-Target Research Collaboration World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Postdoctoral Fellow NEW Research Laboratory Scientist Principal Investigator, In Vitro Biology Associate Scientist Postdoctoral Scholar - O’Neill Lab
- đź“° GPCR Weekly News, July 24 to July 30, 2023
Robert Lefkowitz Lab Postdoc Fellow - Dr. Robert Lefkowitz Lab Senior Research Specialist - Natural Sciences - Surgery Senior Scientist- Membrane
- Dr. Nicola J. Smith - Dr. GPCR Podcast
Nicola Smith, Molecular Pharmacologist, lab head, and senior lecturer at UNSW Sydney.
- đź“° GPCR Weekly News, July 31 to August 6, 2023
Robert Lefkowitz Lab Postdoc Fellow - Dr. Robert Lefkowitz Lab Senior Research Specialist - Natural Sciences - Surgery Senior Scientist- Membrane
- Dr. Simone Promel
Simone Promel / Promel Lab is doing on adhesion #GPCRs.
- Conjugation Strategies for Probe Development
method has several advantages: it is usually very robust, good yields, reagents are found in most chem labs
- Target Residence Time: The Hidden Driver of In Vivo Efficacy
strategy, this is where 40 years of kinetic expertise meet the real questions you’re asking in the lab
- Molecular creativity in drug discovery
. • Training Builds Innovation : Her lab model at Monash is shaping the next generation of GPCR scientists
- GPCRs at Discovery on Target 2026
O'Brien runs a lab at Johns Hopkins that blends cryo-electron microscopy with protein dynamics to build
- Integrated GPCR Drug Discovery: A Structured Framework for Modern Programs
A recurring theme emerges: computational prediction is powerful — but wet-lab validation remains essential
- Early Safety Assays: Identifying Showstoppers in GPCR Drug Discovery Pipelines Early
early decision-making, arming medicinal chemists and project leaders with tools to preempt costly wet-lab






















