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Results found for "GPCR research community"
- Target Residence Time: The Hidden Driver of In Vivo Efficacy
And when receptors are dense (like GPCRs on membranes), this rebinding hits the collisional limit , where
- Free-Energy Simulations Support a Lipophilic Binding Route for Melatonin Receptors
"The effects of the neurohormone melatonin are mediated by the activation of the GPCRs MT1 and MT2 in
- From Lab Logic to Leadership: How Scientific Thinking Holds Back Biotech Operations
. 👉 Most founders don’t even realize they’re still running their company like an academic research group In research, acting on incomplete or shaky data can destroy your credibility. Startups Play by Different Rules — and Most Scientific Founders Miss That A research lab is designed Founders who keep operating like researchers often create internal confusion. When your communication centers on logic and detail instead of clarity and momentum, your team stays
- Synaptic integration of subquantal neurotransmission by co-localized G protein coupled receptors in
Colocalization of different actions of GPCRs provide synaptic integration within presynaptic terminals
- HBx induces hepatocellular carcinogenesis through ARRB1-mediated autophagy to drive the G 1/S cycle
dependent kinase inhibitor 1B; CQ: chloroquine; E2F1: E2F transcription factor 1; FBS: fetal bovine serum; GPCRs
- New role of β-arrestins in MOR signaling
in the U.S., combatting the opioid overdose epidemic has become a mean challenge for the scientific community Opioid receptors belong to class A of G protein-coupled receptors or GPCRs and signaled mainly through Biochem Biophys Res Commun. 2023 Jan 15;640:64-72. doi: 10.1016/j.bbrc.2022.11.098.
- Reflections on My PhD Journey: Lessons Learned
environment, paired with a supportive supervisor, laid the foundation for a fulfilling and productive research Supervisors not only guide your research but also shape your academic and professional growth. These mini "journal clubs" kept me informed about the latest research and sharpened my critical thinking choose a lab and mentor that align with your values and goals, embrace the discipline of structured research challenges will test your resolve, but every small victory along the way shapes you into a stronger researcher
- Exendin-4 Attenuates Remodeling in the Remote Myocardium of Rats After an Acute Myocardial ...
Exendin-4, and possibly through G protein-coupled receptors (GPCRs), increases levels of cAMP and upregulates
- Understanding Orthosteric Binding: The Key to Drug Action
This foundational knowledge guides researchers in the development of new therapeutics. By considering factors like the Langmuir adsorption isotherm and binding curves, researchers can better
- SLAS2022 International Conference and Exhibition
any changes made that will impact our ability to hold the event in-person, we will notify the SLAS community Don't miss the chance to present your innovative research at this year's conference.
- TeachOpenCADD - A teaching platform for computer-aided drug design
both the theoretical as well as practical aspect of these topics, the platform addresses students and researchers Topics are continuously expanded and open for contributions from the community.
- Scientific Isolation: The Real Reason Early Biotechs Lose Traction
strategic inflection points The phrase “after the next dataset…” becomes a company mantra Investor communication experiments slip . ✅ This alone removes much of the latent anxiety in early-stage teams. 3️⃣ Strategic Communication Most communication problems aren’t information gaps.
- The Hidden Burn: How Internal Misalignment Drains Your Biotech’s Runway
Here are the three most common sources of internal drift in early biotech teams: 1️⃣ Scientific versus You communicate with investors without rewriting your story every month. ✅ Science doesn’t just advance
- From Ox Liver to AI: How the History of Pharmacology Shapes Its Future
What do roasted ox liver and AI-powered virtual screening have in common?
