Search Results

Fast-forward a few thousand years, and we’re talking beta receptors, receptor theory, and AI-generated All of it connected. All of it is essential. Dr.

If you have registered, please submit poster abstracts through this form and the short talk selections Targeted and Immuno-oncology Sosei Heptares Adds World-leading Expertise to its Scientific Advisory Board Call

You can submit your poster abstracts using this form and short talks will be selected from abstracts. Global Healthcare Conference CEO Raymond Stevens to Speak at STAT Future Summit on Obesity Therapeutics Call

All molecular components (bosentan, hETB, membrane, and solvent) were represented with an all-atom model bosentan fluctuating randomly in solution is captured using a tip region of the flexible N-terminal tail Bosentan then slides occasionally from the tip to the root of the N-terminal tail (ligand–sliding). The bosentan-captured conformations by the tip-region and root-region of the N-terminal tail correspond

Hiring Won’t Save Your GPCR Drug Discovery Program When a drug discovery program stalls, the default Ambiguous Decision Gates: Molecules advance or stall based on vibes, not criteria.

And here’s the danger: if you can’t tell how  a drug is working, every downstream decision—SAR, lead When Two Mechanisms Look the Same Some of the most difficult calls in pharmacology happen when two different Without the right model, it’s like staring at identical twins—you can’t tell them apart until you see That could be: An orthosteric partial agonist , or An allosteric partial agonist The raw data won’t tell When data alone are ambiguous, models tell you which parameters to control, which conditions to vary,

Randy Hall's study: GPR37L1's role in shaping cortical astrocytes during development Dr. Research Collaboration Addex Therapeutics To Release Half-Year 2023 Financial Results And Host Conference Call

Expand your computational toolkit ➤ Call for Papers: GPCRs: Signal Transduction, Volume II Building on Don’t Fall Behind—Access the Edge You Need 👉 Access all the news and upcoming events ➤ 👉 Already a

All-Atom Molecular Dynamics Simulations Indicated the Involvement of a Conserved Polar Signaling Channel Slow-rising and fast-falling dopaminergic dynamics jointly adjust negative prediction error in the ventral understanding of the role of muscarinic receptors in the molecular pathology and treatment of schizophrenia Call

The course covers basic pharmacology in four weekly segments and is open to all with a free site membership with advanced gastroenteropancreatic neuroendocrine tumors Neurocrine Biosciences Announces Conference Call rescue option for asthma GPCR Events, Meetings, and Webinars January 16 - 19, 2024 | 23rd Annual PEP Talk

Listen to her talk about her work and her transition to PI in Belfast.

Give a talk or present a poster at the Dr. GPCR Summit 2022.

Kenakin talked about  the specific allosteric properties orthosteric drugs cannot offer. control over receptor output, these GPCR pharmacology insights determine whether a series advances or stalls

This is a great opportunity for us to come together and talk GPCRs. Do you want to be part of it? Our Summit is FREE for all Ecosystem site members, which is also free!

In fact, it all began with a phone call (from Bruce Merrifield, no less) encouraging Sakmar to work on pilot data came together, rotation student Ilana Kotliar  joined and pushed the project to scale across all

Find speaker details on the Live Talks page and mark your calendar HERE. Progresses Its GLP-1 Receptor Agonist PF-06954522 into a Phase 1 Trial Andrew Hopkins Inducted into RSC BMCS Hall

"When you talk to patients that have an unmet need, you learn things that no one is thinking about in

The cross-talk between growth factor receptors and GPCRs is an intriguing area of study. of specific phosphorylation events provide a deeper understanding of the molecular basis for cross-talk

Learn the fundamentals of ligand activity, mechanism of action, and GPCR discovery strategy—all at your GPCR Symposia  – On-demand talks from GPCR trailblazers   Watch anytime. Learn from the best.

physiological and pathological relevance of these interactions, since this additional level of molecular cross-talk

Stalled progress. Clarity doesn’t precede action; it follows it.   2️⃣ “Eliminate error at all costs” Labs are built around Trying to eliminate all risk leads to overengineering and stagnation . 👉 Instead of shipping early and The discipline to align a team without all the answers. Real leadership often means choosing without all the answers.

Sandra Berndt talk about new structural perspectives in GPCR-mediated Src family kinase activation.

Joe Clayton from BioTek Instruments talk about automated micro-plate-based methods for quantifying #GPCR

We express our gratitude to the speakers for their excellent talks. If you are interested in giving a talk, contact us at Hello@DrGPCR.com, and if you would like to present

Falling for Computational Chemistry Alessandro’s master’s thesis brought him face to face with his “second Let’s embrace the challenge to study all of them.”  

development, the field has remained too focused on ion channels like NAV1.8 , despite these targets falling

Come attend this month's virtual café talk to see the awesome work of Dr.

If your pitch doesn’t immediately tell them who it’s for, why it matters, and what makes it different They’re trying to understand the opportunity. 👉 Opening with mechanisms forces the listener to do all If your listener doesn’t know what to do next or who should be involved, the conversation stalls. ✅ A If your pitch keeps stalling, stop editing your deck. Start refining your message.

GPR110 belongs to adhesion GPCR and was the functional receptor of N-docosahexaenoyl ethanolamine (also called

Join us for another virtual cafe talk to hear about the amazing work that Dr.