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Results found for "Nobel Prize"
- A broad look into the future of systemic sclerosis
Extracellular vesicles are another novel player to possess disease processes.
- Coincident Regulation of PLCβ Signaling by Gq-Coupled and μOpioid Receptors Opposes Opioid- Mediated
Gβγ regulation of PLCβ3, enhances the potency of the antinociceptive effects of morphine suggesting a novel
- Professor Charlotte Deane Joins Exscientia as Chief Scientist of Biologics AI
intelligence (AI), machine learning, and the design of protein structures in the discovery and development of novel
- 📰 GPCR Weekly News, April 3 to 9, 2023
GPCRs in Cardiology, Endocrinology, and Taste Novel roles for G protein-coupled receptor kinases in cardiac Progressive Technologies and Approaches Revealing Novel GPCR Biology and Drug Development Potential.
- Profiling Immune Cell and Platelet Transcriptomes
hematopoietic stem cells, suggesting a potential role in regulating red blood cell production and offering a novel
- Rhodopsin as a Molecular Target to Mitigate Retinitis Pigmentosa
compounds that have been evaluated as rhodopsin modulators to be considered as leads for the development of novel
- 📰 GPCR Weekly News, March 6 to 12, 2023
Novel Xanomeline-Containing Bitopic Ligands of Muscarinic Acetylcholine Receptors: Design, Synthesis Progressive Technologies and Approaches Revealing Novel GPCR Biology and Drug Development Potential.
- GPCR Buzz of the Week | Sep 23 - 29, 2024
Obesity Pipelines Beyond GLP-1s Septerna Announces Initiation of Phase 1 Clinical Trial with SEP-786, a Novel Cardiology, Endocrinology, and Taste Rap1A Modulates Store-Operated Calcium Entry in the Lung Endothelium: A Novel
- Comparative study of neuropeptide signaling systems in Hemiptera
research provides more knowledge on neuropeptide systems and sets the groundwork for the creation of novel
- APEX2/AUR Biosensor: A Powerful Tool for Protein Interaction and Trafficking
Significant advancements in the cellular biology of G protein-coupled receptors (GPCRs) about a novel
- Although the cannabinoid type-2 receptor (CB2) is highly expressed in the immune system, emerging...
receptor activation, make this receptor an intriguing target for treating schizophrenia, a disease where novel
- 📰 Breaking Down the Latest GPCR Discoveries: a Weekly Update (Nov 27-Dec 3, 2023)
Huntington's disease therapy Rational design of highly stabilized and selective adrenomedullin analogs Novel Carmot Therapeutics Enters into Definitive Merger Agreement with Roche New Clinical Trial Explores Novel
- From Failed Experiments to Predictive GPCR Models
Using virtual screening, he was able to identify novel ligands that aligned with experimental findings on virtual screening from commercial compound libraries, the work inevitably reaches a point where novel
- 📰 GPCR Weekly News, April 10 to 16, 2023
GPCR Binders, Drugs, and more Discovery of SYD5115, a novel orally active small molecule TSH-R antagonist Progressive Technologies and Approaches Revealing Novel GPCR Biology and Drug Development Potential.
- Neuropeptide S Encodes Stimulus Salience in the Paraventricular Thalamus
striking deficit of both NPS receptor (NPSR1) and NPS precursor knockout mice in fear extinction or novel
- A Setmelanotide-like Effect at MC4R Is Achieved by MC4R Dimer Separation
Recent studies introducing setmelanotide, a novel synthetic MC4R agonist, suggest a predominant role
- GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome activation
CLH536, a novel GPR84 antagonist discovered by us, suppresses colitis by reducing the polarization and
- Confo Therapeutics Doses First Subjects In Phase 1 Clinical Trial Of CFTX-1554 For The Treatment ...
been dosed in the company’s Phase 1, first-in-human trial of their clinical candidate CFTX-1554, a novel
- Hop in the Time Machine with GPCR: Unraveling the Future of Research! ⦿ Nov 24 - Dec 1, 2024
GPCR University 🎥 Recorded GPCR Courses and Symposia / Summit 💲 Special Pricing on GPCR courses prognosis in nasopharyngeal carcinoma RNAi library screening reveals Gβ1, Casein Kinase 2 and ICAP-1 as novel
- Maria’s Travel Blogs: ACSMEDI-EFMC Medicinal Chemistry Frontiers 2025
Frontiers 2025 , a conference organized by both the EFMC and the ACSMEDI, in an effort to share the most novel
- 📰 GPCR Weekly News, February 27 to March 5, 2023
Developing novel antifungals: lessons from G protein-coupled receptors. Progressive Technologies and Approaches Revealing Novel GPCR Biology and Drug Development Potential.
- Structure-Based Discovery of Negative Allosteric Modulators of the Metabotropic Glutamate Receptor 5
revealed the location of allosteric binding sites and opened new opportunities for the discovery of novel
- 📰 GPCR Weekly News, December 18 to 31, 2023
Endocrinology, and Taste Beta cell primary cilia mediate somatostatin responsiveness via SSTR3 Inhibition of a novel Voyager Therapeutics Enters Capsid License Agreement and Strategic Collaboration with Novartis to Advance Novel
- Structure-Based Discovery of Negative Allosteric Modulators of the Metabotropic Glutamate Receptor 5
revealed the location of allosteric binding sites and opened new opportunities for the discovery of novel
- Illuminating GPCR Research: FRET and BRET-Based Sensors Shed Light on Cellular Signaling
undoubtedly continue to propel our quest to unravel the complexities of GPCR signaling and pave the way for novel Jiang, L.I., et al., Use of a cAMP BRET sensor to characterize a novel regulation of cAMP by the sphingosine
- GPCR Updates: Celebrating Breakthroughs, New Course Launches Soon, and Exclusive Discounts! | Aug 26 - Sep 1, 2024
Don’t miss this chance to benefit from our early bird pricing and premium content. Russell to Board of Directors Adiso Announces Groundbreaking Research Highlighting ADS024 a Novel Oral
- Precise druggability of the PTH type 1 receptor
modulators of PTHR signaling that could be extended to GPCRs to expedite discoveries of small molecules as novel
- 📰 GPCR Weekly News, February 20 to 26, 2023
Structural and Molecular Insights into GPCR Function Structure-based design of novel melanin-concentrating Progressive Technologies and Approaches Revealing Novel GPCR Biology and Drug Development Potential.
- Comparative studies of AlphaFold, RoseTTAFold and Modeller: a case study involving the use of...
This work directly compares the performance of these novel deep learning-based protein modeling methods
- Cell-Type-Specific Effects of the Ovarian Cancer G-Protein Coupled Receptor (OGR1) on Inflammation..
Our results suggest that strategies to selectively target OGR1 expression may represent a novel therapeutic





