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- Ben Clements on Rescuing Opioids with GPCR Modulators
With collaborations across medicinal chemistry and neuropathic pain research, Ben is bridging molecule
- Inverse Agonists, Lymphatic Fixes & β-arrestin Tricks
Plus, check out the latest Dr. GPCR tools and key moves in the biotech world. Dr. GPCR University Cheatsheet is your quick-start guide to everything we offer—no downloads, no digging Explore the Cheatsheet GPCR Publication Highlights — Minimal Structural Variation of GPR84 Full Agonist
- 🎄 Have Yourself a Merry Little GPCRmas! ❄ Dec 9 - 15, 2024
XXIII GEM Meeting in 2025 April 3 - 6, 2025 | ASPET 2025 April 14 - 17, 2025 | 20th Drug Discovery Chemistry Scientist - Biology Scientist I Cell Biology - Tectonic Therapeutic Senior Principal Scientist, Medicinal Chemistry GPCR, GPR65 on fibroblast-like synoviocytes contributes to inflammatory joint pain Regulation of the chemokine
- Hop in the Time Machine with GPCR: Unraveling the Future of Research! ⦿ Nov 24 - Dec 1, 2024
Hauser Calcineurin-fusion facilitates cryo-EM structure determination of a Family A GPCR Jun Xu , Geng Chen To fully explore our Ecosystem, scroll to the footer and check out our Map! We're about to reveal our University CheatSheet —a sneaky peek at all our talks, presentations, and courses XXIII GEM Meeting in 2025 April 3 - 6, 2025 | ASPET 2025 April 14 - 17, 2025 | 20th Drug Discovery Chemistry receptor probed by molecular dynamics simulations, NMR and pharmacological studies High-affinity ELR+ chemokine
- 🤯Mind-blowing GPCR Scoops! Discover the Latest Breakthroughs! ⦿ Nov 18 - 24, 2024
🕵️♂️We'll soon be unveiling our University CheatSheet! Major Announcement! XXIII GEM Meeting in 2025 April 3 - 6, 2025 | ASPET 2025 April 14 - 17, 2025 | 20th Drug Discovery Chemistry Scientist - Biology Scientist I Cell Biology - Tectonic Therapeutic Senior Principal Scientist, Medicinal Chemistry
- ⛵Sailing the GPCR Seas: Your Weekly Research Voyage! ⦿ Nov 11 - 17, 2024
XXIII GEM Meeting in 2025 April 3 - 6, 2025 | ASPET 2025 April 14 - 17, 2025 | 20th Drug Discovery Chemistry Pharmacology GPCR Jobs Scientist I Cell Biology - Tectonic Therapeutic Senior Principal Scientist, Medicinal Chemistry cell function Protein Biochemist/Structural Biologist Senior Scientist/Staff Scientist, Computational Chemistry receptor GPR68 supports AML cells through the calcium/calcineurin pro-survival pathway and confers chemoresistance obesity and skeletal muscle dysfunction via improving skeletal muscle Srl/MRCC-I pathway in Drosophila Chemogenetic
- What's Going On with GPCRs?! Find Out in This Week's Update! ⦿ Nov 4 - 10, 2024
XXIII GEM Meeting in 2025 April 3 - 6, 2025 | ASPET 2025 April 14 - 17, 2025 | 20th Drug Discovery Chemistry GPCR Jobs Scientist I Cell Biology - Tectonic Therapeutic NEW Senior Principal Scientist, Medicinal Chemistry cell function Protein Biochemist/Structural Biologist Senior Scientist/Staff Scientist, Computational Chemistry
- Harnessing Deep Mutational Scanning for Enhanced Drug Discovery
This data can guide the modification of the chemical structure of the lead compounds to improve potency
- Exciting GPCR Events for Next Year! + GPCR Weekly Rocket Launch ⦿ Oct 28 - Nov 3, 2024
al. for their excellent work on Receptor determinants for ß-arrestin functional specificity at C-X-C chemokine Meeting in 2025 NEW April 3 - 6, 2025 | ASPET 2025 NEW April 14 - 17, 2025 | 20th Drug Discovery Chemistry cell function Protein Biochemist/Structural Biologist Senior Scientist/Staff Scientist, Computational Chemistry like and β2 adrenergic receptors Receptor determinants for ß-arrestin functional specificity at C-X-C chemokine receptors for the treatment of alcohol use disorders: Opportunities and hurdles for clinical development Chemokine
- Embark on a GPCR Adventure: Your Weekly Research Expedition! | Oct 21-27, 2024
cell function Protein Biochemist/Structural Biologist Senior Scientist/Staff Scientist, Computational Chemistry
- Class B1 GPCR Dimerization: Unveiling Its Role in Receptor Function and Signaling
Chem Rev, 2017. 117 (1): p. 111-138.
- Profiling Immune Cell and Platelet Transcriptomes
For instance, the expression of specific chemokine receptors in monocytes and macrophages indicates their to elucidate their specific contributions.Moreover, the study's findings on the unique expression of chemokine
- Discover the Hottest GPCR News of the Week: Oct 7-13, 2024!
cell function Protein Biochemist/Structural Biologist Senior Scientist/Staff Scientist, Computational Chemistry Molecular Insights into GPCR Function Structural insights into KSHV-GPCR constitutive activation and CXCL1 chemokine
- GPCR Weekly Whirlwind: Top Receptor Highlights from Sep 30 - Oct 6, 2024!
🌟 Get ready - the full agenda is now available; check it HERE ! expanding GPCR landscape The Royal Swedish Academy of Sciences has decided to award the Nobel Prize in Chemistry cell function Protein Biochemist/Structural Biologist Senior Scientist/Staff Scientist, Computational Chemistry
- GPCR Buzz of the Week | Sep 23 - 29, 2024
Discovery on Target October 2024 | Biologics US 2024 October 2 - 4, 2024 | 9th GPCRs in Medicinal Chemistry cell function Protein Biochemist/Structural Biologist Senior Scientist/Staff Scientist, Computational Chemistry Postdoctoral research position Adhesion GPCRs The G Protein-Coupled Receptor GPR56 Is an Inhibitory Checkpoint
- AlphaFold’s Breakthrough in GPCR Research: Revolutionizing Discovery, Yet Awaiting Experimental Proof
AlphaFold-predicted models revealed distinct ligand-binding site shapes, enabling the prioritization of different chemotypes Nat Chem Biol 7 , 769-778 (2011). https://doi.org/10.1038/nchembio.662 Diaz-Holguin, A.
- 📢 Early Bird Registration Ends Tomorrow! | Sep 16 - 22, 2024
the exciting world of incorporating machine learning, innovative biophysical methods, and medicinal chemistry 🌟 Exciting news - the complete agenda is live; check it out HERE ! Discovery on Target October 2024 | Biologics US 2024 October 2 - 4, 2024 | 9th GPCRs in Medicinal Chemistry cell function Protein Biochemist/Structural Biologist Senior Scientist/Staff Scientist, Computational Chemistry
- Unlock the Future of GPCR Science: Breakthroughs and Courses Await | Sep 2 - Sep 8, 2024
in GPCR-targeted drug design, including machine learning, new biophysical techniques, and medicinal chemistry implications for drug development DeepCure team is excited to welcome Justin Potnick, to our Medicinal Chemistry Discovery on Target October 2024 | Biologics US 2024 October 2 - 4, 2024 | 9th GPCRs in Medicinal Chemistry Postdoc in Molecular Pharmacology - The Hauser Group Senior Scientist/Staff Scientist, Computational Chemistry
- APEX2/AUR Biosensor: A Powerful Tool for Protein Interaction and Trafficking
This study, published in Nature Chemical Biology, highlights the role of the chaperone protein DNAJC13
- GPCR Updates: Celebrating Breakthroughs, New Course Launches Soon, and Exclusive Discounts! | Aug 26 - Sep 1, 2024
GPCR-targeted drugs, including the role of machine learning, new biophysical techniques, and medicinal chemistry Discovery on Target October 2024 | Biologics US 2024 October 2 - 4, 2024 | 9th GPCRs in Medicinal Chemistry Postdoc in Molecular Pharmacology - The Hauser Group NEW Senior Scientist/Staff Scientist, Computational Chemistry GPCR Research A nondestructive membrane engineering method using an amphiphilic polymer Labeling of CC Chemokine
- Decoding GPCR Function: The Role of Mutagenesis in Rational Drug Discovery
Journal of Medicinal Chemistry , 41 (16), 2911-2927. Carlsson, J., Yoo, L., Gao, Z. G., Irwin, J. Journal of Medicinal Chemistry , 53 (9), 3748-3755. Di Roberto, R. B., Chang, B., & Peisajovich, S.
- 📢 GPCR Update: August 19-25, 2024 | Thrilling Announcement: New Pharmacology Course Dates & Exclusive Discounts Inside!
Discovery on Target October 2024 | Biologics US 2024 October 2 - 4, 2024 | 9th GPCRs in Medicinal Chemistry
- 📰 GPCR Weekly Buzz: Exciting Schedule Shifts for Principles of Pharmacology I & II | August 12-18, 2024
quinone reductase-2 with neuroprotective and neurogenic properties GPCRs in Oncology and Immunology Chemoattractant assays in drug discovery October 2024 | Biologics US 2024 October 2 - 4, 2024 | 9th GPCRs in Medicinal Chemistry
- 📰 GPCR Buzz: August 5-11, 2024 | Top Highlights from DrGPCR University!
Check out what’s coming in September and October: Sign up for both courses now and score a 25% early s Check out the details of each course below: Open to the Public: Enrollment is Now Available! assays in drug discovery October 2024 | Biologics US 2024 October 2 - 4, 2024 | 9th GPCRs in Medicinal Chemistry
- Dr. GPCR University registration is now open! Secure your spot now!
consequences of spatial, temporal and ligand bias of G protein-coupled receptors Inverse Regulation of C-C Chemokine assays in drug discovery October 2024 | Biologics US 2024 October 2 - 4, 2024 | 9th GPCRs in Medicinal Chemistry
- Unlocking the Future of Medicine: Advancements in GPCR Research
This week's highlight includes congrats to Omolade Otun, Chris de Graaf, Cherine Bechara, et al. for their work on Conformational dynamics underlying atypical chemokine receptor 3 activation Michael Trogdon from July 15th to 21st, 2024 GPCR Activation and Signaling Conformational dynamics underlying atypical chemokine Cyanobacterium Fluorophore-Labeled Pyrrolones Targeting the Intracellular Allosteric Binding Site of the Chemokine assays in drug discovery October 2024 | Biologics US 2024 October 2 - 4, 2024 | 9th GPCRs in Medicinal Chemistry
- Exploring the Breakthroughs in GPCR Research
Check out our GPCR coverage for this week. assays in drug discovery October 2024 | Biologics US 2024 October 2 - 4, 2024 | 9th GPCRs in Medicinal Chemistry
- 📰 GPCR Weekly News, June 24 to 30, 2024
assays in drug discovery October 2024 | Biologics US 2024 October 2 - 4, 2024 | 9th GPCRs in Medicinal Chemistry
- 📰 GPCR Weekly News, June 17 to 23, 2024
assays in drug discovery October 2024 | Biologics US 2024 October 2 - 4, 2024 | 9th GPCRs in Medicinal Chemistry
- 📰 GPCR Weekly News, June 10 to 16, 2024
advances and challenges Structural and Molecular Insights into GPCR Function Structural perspectives on chemokine 2024 | FENS Forum 2024 October 2024 | Biologics US 2024 October 2 - 4, 2024 | 9th GPCRs in Medicinal Chemistry
