Search Results
Results found for "class A GPCR"
- The Dr. GPCR Podcast is back! After a long break, a new episode will be released today 🎧 Join us in 2025 with a year filled with GPCRs, as we share with specialists about their career paths, the latest breakthroughs, their advice, and inspiring stories. 📅 Ep. 157 drops today January 9th at 10 AM EST. Don’t miss it! ✅ Stay tuned & subscribe at https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-157-with-dr.-nagarajan-vaidehi | Dr. GPCR EcosystemGPCR Podcast is back! After a long break, a new episode will be released today 🎧 Join us in 2025 with a year filled with GPCRs ✅ Stay tuned & subscribe at https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-157-with-dr. GPCR Podcast The Dr. GPCR Podcast is back! ✅ Stay tuned & subscribe at https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ep-157-with-dr. 
- A high-resolution deep mutational scan of MC4R reveals how thousands of genetic variants impact obesity-linked signaling pathways and highlights new opportunities for precision drug discovery Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️ https://www.ecosystem.drgpcr.com/receptor-activation-and-signaling/high-resolution-deep-mutational-scanning-of-the-melanocortin-4-receptor-enables-target-characterization-for-drug-discovery #gpcr#drgpcr | Dr. GPCR EcosystemGPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️ https://www.ecosystem.drgpcr.com high-resolution-deep-mutational-scanning-of-the-melanocortin-4-receptor-enables-target-characterization-for-drug-discovery #gpcr #drgpcr Published on May 5, 2025 Category GPCR Weekly News A high-resolution deep mutational scan of GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️ https://www.ecosystem.drgpcr.com high-resolution-deep-mutational-scanning-of-the-melanocortin-4-receptor-enables-target-characterization-for-drug-discovery #gpcr 
- Disrupting VIPR2 dimerisation halts breast cancer spread—could TM3-4 peptides be the next breakthrough in targeted cancer therapy? Check out the latest GPCR news in the Ecosystem today! You’ll need to register but don’t worry, it’s Free! ➡️ https://www.ecosystem.drgpcr.com/gpcrs-in-oncology-and-immunology/dimerisation-of-the-vip-receptor-vipr2-is-essential-to-its-binding-vip-and-g%CE%B1i-proteins%2C-and-to-its-functions-in-breast-cancer-cells #gpcr#drgpcr | Dr. GPCR EcosystemCheck out the latest GPCR news in the Ecosystem today! ➡️ https://www.ecosystem.drgpcr.com/gpcrs-in-oncology-and-immunology/dimerisation-of-the-vip-receptor-vipr2 is-essential-to-its-binding-vip-and-g%CE%B1i-proteins%2C-and-to-its-functions-in-breast-cancer-cells #gpcr #drgpcr Published on May 12, 2025 Category GPCR Weekly News Disrupting VIPR2 dimerisation halts breast Check out the latest GPCR news in the Ecosystem today! 
- 🚀 New Learning Opportunities at Dr.GPCR University! Expand your GPCR expertise with exclusive workshops, interactive courses, and an on-demand library—all in one place! ✅ Register for upcoming sessions ✅ Access expert-led content anytime ✅ Enjoy premium benefits & exclusive resources 📢 Don’t miss out—start your learning journey today! 🔗 https://www.ecosystem.drgpcr.com/gpcr-courses #GPCR #DrGPCR #LifelongLearning #drugdiscovery #pharmacology | Dr. GPCR EcosystemExpand your GPCR expertise with exclusive workshops, interactive courses, and an on-demand library—all 🔗 https://www.ecosystem.drgpcr.com/gpcr-courses #GPCR #DrGPCR #LifelongLearning #drugdiscovery #pharmacology Published on February 25, 2025 Category GPCR Weekly News 🚀 New Learning Opportunities at Dr.GPCR University Expand your GPCR expertise with exclusive workshops, interactive courses, and an on-demand library—all 🔗 https://www.ecosystem.drgpcr.com/gpcr-courses #GPCR #DrGPCR #LifelongLearning #drugdiscovery #pharmacology 
- 🔥 New Course Alert! “Development of GPCR Ligands as Therapeutic Drugs” with Dr. Terry Kenakin is here! Spots are filling up fast—Premium Members get 25% off! This advanced course is exclusively available in the Ecosystem, so don’t miss your chance to learn from the best. 🔹 Secure your spot now! 👉 https://www.ecosystem.drgpcr.com/event-details-registration/development-of-gpcr-ligands-as-therapeutic-drugs #gpcr #drgpcr #pharmacolgy #drugdiscovery #research | Dr. GPCR Ecosystem“Development of GPCR Ligands as Therapeutic Drugs” with Dr. Terry Kenakin is here! 👉 https://www.ecosystem.drgpcr.com/event-details-registration/development-of-gpcr-ligands-as-therapeutic-drugs #gpcr #drgpcr #pharmacolgy #drugdiscovery #research Published on February 24, 2025 Category Dr. GPCR Courses 🔥 New Course Alert! “Development of GPCR Ligands as Therapeutic Drugs” with Dr. #gpcr #drgpcr #pharmacolgy #drugdiscovery #research Recent Articles Previous Next 
- Adenosine A3 receptor has been proposed to have significant roles in metabolism and immune responses. Check out this study to understand how it affects metabolic dysfunction-associated steatotic liver progression. Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️https://buff.ly/42b6ra3 #gpcr #drgpcr | Dr. GPCR EcosystemGPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️https://buff.ly/42b6ra3 #gpcr #drgpcr Published on January 16, 2025 Category GPCR Weekly News Adenosine A3 receptor has been proposed GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️https:// www.ecosystem.drgpcr.com Breakthroughs this week: Potentiation of GPCR signaling by ATP and sugar monophosphates; Pharmacology Oct 14 Assay Volume Control: Your GPCR Drug Discovery Power Lever If you want cleaner decisions, start 
- Our Sponsors for Adhesion GPCR Workshop 2024 | Dr. GPCR EcosystemMeet the sponsors who make the Adhesion GPCR Workshop 2024 possible, supporting global collaboration and innovation in GPCR research. Home Registration Full Agenda Venue Travel Tips Sponsors Special Issue on Adhesion GPCRs OUR SPONSORS Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Sponsor Us Platinum Sponsors Learn more about the Adhesion GPCR workshop 2024 Up About the event Learn more about the Adhesion GPCR 
- Ep 155 with Endocrine Metabolic GPCR OrganizersGPCR Podcast << Back to podcast list Re-cap of Endocrine Metabolic GPCR 2024 with the Organizers About Aylin Hanyaloglu on the web LinkedIn Endocrine Metabolic GPCRs Researchgate Twitter Imperial College GPCR About Dr. Caroline Gorvin "Dr. GPCR About Dr. Alejandra Tomas "Dr. GPCR Enjoying the Dr. GPCR Podcast? Leave a Review. 
- Revvity | Dr. GPCR EcosystemView Reagents Explore Revvity’s GPCR Assay Technologies Tools designed to illuminate every step of GPCR GPCR, the global nonprofit platform dedicated to advancing GPCR research and drug discovery, is proud GPCR Podcast 6 days ago 4 min read The Truth About GPCR Product Launches: Years in the Making What it GPCR Podcast Sep 26 3 min read Dr. GPCR Ecosystem. Dr. GPCR News Sep 22 2 min read Dr. GPCR Ecosystem Partner Contact Revvity 
- A casual postdoc in Santiago. A bold yes during the pandemic. Now? A biotech startup solving GPCR challenges worldwide 🌎 Celtarys Research didn’t follow the script, and neither does their chemistry. 🎧 In this week’s episode, Dr. Maria Majellaro talks about trusting your gut, learning to lead, and building science that scales. ✳️Celtarys is ready to support your assay development. Get to know more: Celtarys Research | Dr. GPCR Ecosystem | Dr. GPCR Ecosystem #GPCRtools #GPCRtrainingProgram #DrGPCR #BiotechLeadership | Dr. GPCR EcosystemGPCR Ecosystem | Dr. GPCR Ecosystem #GPCRtools #GPCRtrainingProgram #DrGPCR #BiotechLeadership Published on June 17, 2025 GPCR Podcast A casual postdoc in Santiago. A bold yes during the pandemic. Now? GPCR Ecosystem | Dr. GPCR Ecosystem #GPCRtools #GPCRtrainingProgram #DrGPCR #BiotechLeadership Recent Articles Previous Next 
- master gpcr pharmacologic models before its too late | Dr. GPCR EcosystemHome → Flash News → master gpcr pharmacologic models before its too late Published on July 11, 2025 Category GPCR Weekly News Most GPCR teams aren’t failing because of bad science. This week’s GPCR Weekly News helps you fix that. Yamina’s Corner exposes the silent drift killing GPCR programs (and how to reverse it). utm_content=bufferd9b30&utm_medium=social&utm_source=twitter.com&utm_campaign=buffer #GPCR #Pharmacology 
- encoding and decoding selectivity and promiscuity in the human chemokine GPCR interaction network | Dr. GPCR EcosystemHome → Flash News → encoding and decoding selectivity and promiscuity in the human chemokine GPCR interaction network Published on July 7, 2025 Category GPCR Weekly News How do chemokines and GPCRs decode selectivity conserved and variable sequence–structure elements govern interaction logic across 46 chemokines and 23 GPCRs unstructured regions ♦️ Includes a web tool + viral chemokine engineering demo This is a must-read for GPCR ligand engineers. ➡️ Read the paper: https://www.cell.com/cell/fulltext/S0092-8674(25)00398-8 #DrGPCR #GPCR 
- What’s one key piece of advice from Ian Chronis in Ep.164 of the Dr.GPCR Podcast?Listen to other scientists’ research—it’s a great way to stay motivated and inspired 🚀 Don’t miss this insightful conversation on GPCRs, pharmacology, and scientific discovery! ✅ https://buff.ly/FTB69y9 #GPCR #DrGPCR #SciencePodcast #Pharmacology #CancerResearch | Dr. GPCR Ecosystemresearch—it’s a great way to stay motivated and inspired 🚀 Don’t miss this insightful conversation on GPCRs ✅ https://buff.ly/FTB69y9 #GPCR #DrGPCR #SciencePodcast #Pharmacology #CancerResearch Published on April GPCR Podcast What’s one key piece of advice from Ian Chronis in Ep.164 of the Dr.GPCR Podcast? ✅ https://buff.ly/FTB69y9 #GPCR #DrGPCR #SciencePodcast #Pharmacology #CancerResearch Recent Articles Breakthroughs this week: Potentiation of GPCR signaling by ATP and sugar monophosphates; Pharmacology 
- Summit | Dr. GPCR EcosystemJoin the forefront of GPCR research at the Dr. GPCR Summit! Uncover groundbreaking insights in GPCR science together. Learn more. Dr. GPCR Summit We live in a new world, and we think it's an opportunity to try new things and use current technologies to help us connect and spread scientific advances in the GPCR field. Our goal is to allow everyone in the GPCR community to get access to the talks through the entire length 
- Did you know that cell types can affect the GPCR-mediated signalling cascade? Check out this paper to know how different cell types affect the A2BR-mediated calcium signalling system. Check out the latest GPCR news in the Ecosystem today! You’ll need to register but don’t worry, it’s Free! ➡️https://www.ecosystem.drgpcr.com/receptor-activation-and-signaling/a2b-adenosine-receptor-triggered-intracellular-calcium-mobilization%3A-cell-type-dependent-involvement-of-gi%2C-gq%2C-gs-proteins-and-protein-kinase-c #gpcr #drgpcr | Dr. GPCR EcosystemHome → Flash News → Did you know that cell types can affect the GPCR-mediated signalling cascade? Check out the latest GPCR news in the Ecosystem today! #drgpcr Published on January 14, 2025 Category GPCR Weekly News Did you know that cell types can affect the GPCR-mediated signalling cascade? Check out the latest GPCR news in the Ecosystem today! 
- ep 175 with jens carlsson clip 1 | Dr. GPCR EcosystemJens Carlsson’s lab at Uppsala University is redefining GPCR drug discovery with predictive molecular GPCR Podcast “Explain” is no longer enough. Can your model actually predict the outcome of a GPCR experiment? At Uppsala University, Dr. drug discovery. 🎧 Explore how predictive modeling is reshaping GPCR science in this Dr. GPCR Podcast episode: model predict discover #DrGPCR #GPCR #MolecularModeling #PredictivePharmacology 
- Do you know that dilated cardiomyopathy, a disease that makes it harder for the heart to pump blood to the rest of the body, results from the deficiency of Latrophilin-2? Check out this paper to understand the function of Latrophilin-2 and how it leads to dilated cardiomyopathy. Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox. | Dr. GPCR EcosystemGPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox. Published on October 31, 2024 Category GPCR Weekly News Do you know that dilated cardiomyopathy, a disease GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox. ➡️ https:// www.ecosystem.drgpcr.com /gpcrs-in-cardiology-endocrinology-and-taste/latrophilin-2-deletion-in-cardiomyocyte-disrupts-cell-junction 
- We’re proud to welcome Celtarys as our media partner! Known for their fluorescent ligand innovation, Celtarys is helping researchers make biology visible, faster, smarter, and with more precision. Their chemistry speaks the language of biology, and now, they’re speaking to the global GPCR community through this powerful collaboration. 🔗 Explore Celtarys on the Dr. GPCR Ecosystem: https://www.ecosystem.drgpcr.com/celtarys-research-dr-gpcr-ecosystem #DrGPCR #GPCRtools #FluorescentLigands #BiotechInnovation | Dr. GPCR EcosystemTheir chemistry speaks the language of biology, and now, they’re speaking to the global GPCR community GPCR Ecosystem: https://www.ecosystem.drgpcr.com/celtarys-research-dr-gpcr-ecosystem #DrGPCR #GPCRtools Their chemistry speaks the language of biology, and now, they’re speaking to the global GPCR community GPCR Ecosystem: https://www.ecosystem.drgpcr.com/celtarys-research-dr-gpcr-ecosystem #DrGPCR #GPCRtools 
- Yamina's Corner | Dr. GPCR EcosystemTurn GPCR discovery chaos into clarity—Yamina’s Corner offers expert GPCR strategy, CRO guidance, and critical scientific red flags and technical gaps in GPCR assets before committing capital. Berchiche, and I understand the intricate challenges of GPCR drug discovery. GPCR Calendly ©2023-2025 All rights reserved by FindYooour, LLC & Dr. GPCR Corp Proudly created with Wix.com 
- Did you know that A2B adenosine receptor-triggered calcium mobilization varies by cell type? A recent study explores how Gi, Gq, Gs proteins, and PKC contribute differently to intracellular Ca²⁺ signaling, revealing a more complex regulation than previously thought. Subscribe to the Dr. GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️https://www.ecosystem.drgpcr.com/receptor-activation-and-signaling/a2b-adenosine-receptor-triggered-intracellular-calcium-mobilization%3A-cell-type-dependent-involvement-of-gi%2C-gq%2C-gs-proteins-and-protein-kinase-c #gpcr #drgpcr #metabolism #obesity | Dr. GPCR EcosystemGPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️https://www.ecosystem.drgpcr.com a2b-adenosine-receptor-triggered-intracellular-calcium-mobilization%3A-cell-type-dependent-involvement-of-gi%2C-gq%2C-gs-proteins-and-protein-kinase-c #gpcr #drgpcr #metabolism #obesity Published on March 10, 2025 Category GPCR Weekly News Did you know that GPCR Newsletter 📰 and get the latest GPCR News delivered to your inbox ➡️ https:// www.ecosystem.drgpcr.com a2b-adenosine-receptor-triggered-intracellular-calcium-mobilization%3A-cell-type-dependent-involvement-of-gi%2C-gq%2C-gs-proteins-and-protein-kinase-c #gpcr 
- Ep 152 with Dr Arthur ChristopoulosGPCR Podcast << Back to podcast list A Brief History of allosteric modulation with Dr. His research focuses on novel paradigms of drug action at GPCRs, particularly allosteric modulation and They also delved into the different signaling of Class B receptors and the potential for modulation at They also discussed their upcoming trips to the GPCR Colloquium in California and current research in GPCR Podcast? Leave a Review. 
- What do GPCRs, acidic endosomes, and cancer immunotherapy have in common? Find out in our latest episode featuring Ian Chronis, where we explore the surprising ways GPR65 signals in different environments! ✅ Tune in: https://buff.ly/FTB69y9 #GPCR #DrGPCR #SciencePodcast | Dr. GPCR EcosystemHome → Flash News → What do GPCRs, acidic endosomes, and cancer immunotherapy have in common? ✅ Tune in: https://buff.ly/FTB69y9 #GPCR #DrGPCR #SciencePodcast Published on April 15, 2025 Category GPCR Podcast What do GPCRs, acidic endosomes, and cancer immunotherapy have in common? ✅ Tune in: https://buff.ly/FTB69y9 #GPCR #DrGPCR #SciencePodcast Recent Articles Previous Next 
- Dr. GPCR Podcastscientist, student, or just curious, you’ll hear about discoveries, career stories, and the latest GPCR GPCR Podcast? Leave a Review. 
- Do you know we can discover allosteric modulators that bind to the intracellular allosteric binding site to better fine-tune the GPCRs’ activity? Check out the development of a NanoBRET assay platform to detect intracellular ligands for the chemokine receptors CCR6 and CXCR1. Check out the latest GPCR news in the Ecosystem today! You’ll need to register but don’t worry, it’s Free! | Dr. GPCR Ecosystemallosteric modulators that bind to the intracellular allosteric binding site to better fine-tune the GPCRs Check out the latest GPCR news in the Ecosystem today! Published on October 29, 2024 Category GPCR Weekly News Do you know we can discover allosteric modulators that bind to the intracellular allosteric binding site to better fine-tune the GPCRs’ activity? Check out the latest GPCR news in the Ecosystem today! 
- Plenary Lecture | Adhesion GPCR Workshop 2024 | Dr. GPCR EcosystemFull Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program HERE < Back to Full Agenda Plenary Lecture Identification and Functional Characterization of Adhesion GPCRs Our first main research aspect is the identification of endogenous ligand of GPCRs. Our third main research aspect is working mechanism of GPCR. (Cell 2021, 2023, Nature 2023b), bile acids or its derivatives by GPCRs (Nature 2020)." 
- GPCRs regulate key biological processes, but how exactly do inhibitory Gαi proteins control signal transduction beyond adenylyl cyclase suppression? New research sheds light on these pathways! ✨ Want to learn more? Did you know that we work hard to bring you the most recent GPCR News, weekly? Catch up today in the Ecosystem using your free site membership! | Dr. GPCR EcosystemHome → Flash News → GPCRs regulate key biological processes, but how exactly do inhibitory Gαi proteins Did you know that we work hard to bring you the most recent GPCR News, weekly? Published on October 22, 2024 Category GPCR Weekly News GPCRs regulate key biological processes, but Did you know that we work hard to bring you the most recent GPCR News, weekly? receptor-activation-and-signaling/germline-mutations-in-a-g-protein-identify-signaling-cross-talk-in-t-cells #GPCR 
- Logo Contest for Adhesion GPCR Workshop 2024 | Dr. GPCR EcosystemSubmit your design to represent the Adhesion GPCR Workshop and inspire our global community. LOGO CONTEST Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Register Rules Artist-scientists must be registered to attend the adhesion GPCR workshop 2024 in Mexico City. Register for the Adhesion GPCR 2024 Learn more about the Adhesion GPCR workshop 2024 Up About the event Learn more about the Adhesion GPCR workshop 2024 and its preliminary program. 
- from curiosity to breakthrough ajay yekkirala on gpcr innovationGPCR Podcast << Back to podcast list From Curiosity to Breakthrough: Ajay Yekkirala on GPCR Innovation , a company using machine learning to unlock new GPCR-targeted therapies. Why This Matters Translating basic GPCR science into actual medicines is broken. Ajay’s work sits at the intersection of GPCR biology, AI, and translational medicine. led Ajay Yekkirala to reshape the future of GPCR-targeted medicine. Enjoying the Dr. GPCR Podcast? 
- 🚨 Exciting Opportunity for Professionals in Drug Development! 🚨 Register today for a one-of-a-kind online course at Dr. GPCR University: "Development of GPCR Ligands as Therapeutic Drugs." 🗓 Dates: March 20 - April 10, 2025 ⏰ Time: Thursdays, 10:00 AM - 11:30 AM (EST) This advanced course is essential for anyone working in drug development and focuses on: The essentials of new drug development Key pharmacokinetic elements (absorption, distribution, clearance) Hepatic metabolism and the Cytochrome P450 system Drug safety and toxicology (including drug-drug interactions) And much more! Gain deep insights into GPCR drug candidates and learn the critical assays and techniques required to bring therapeutic molecules to life. 🚨 Only 25 spots available — register now! 💡 This is a great opportunity for both academia and industry professionals. Sessions will be live, and you’ll also have 1:1 discussion time with the instructor. Full PDFs of the slides will be available! 🔗 https://buff.ly/lVEcRUc #GPCR #DrugDevelopment #Pharmacokinetics #TherapeuticDrugs #OnlineCourse #DrGPCRUniversity #PharmaceuticalIndustry | Dr. GPCR EcosystemGPCR University: "Development of GPCR Ligands as Therapeutic Drugs." 🗓 Dates: March 20 - April 10, 2025 Gain deep insights into GPCR drug candidates and learn the critical assays and techniques required to 🔗 https://buff.ly/lVEcRUc #GPCR #DrugDevelopment #Pharmacokinetics #TherapeuticDrugs #OnlineCourse # GPCR Courses 🚨 Exciting Opportunity for Professionals in Drug Development! GPCR University: "Development of GPCR Ligands as Therapeutic Drugs." 🗓 Dates: March 20 - April 10, 2025 
- 🚀 New Workshop: Practical Quantification of Allosteric Modulation Join Dr. Terry Kenakin on May 1st, 2025, for an advanced live workshop on allosteric modulators in GPCR drug discovery. Learn how to: ✔️ Identify, measure, and quantify allosteric properties ✔️ Apply functional allosteric models to determine mechanisms of action ✔️ Confirm allostery through kinetic analysis 📅 Date: May 1st, 2025 ⏳ Registration deadline: April 18th 📍 Live on Google Meet 🔗 Register now: https://www.ecosystem.drgpcr.com/event-details-registration/practical-quantification-of-allosteric-modulation #GPCR #Allostery #DrugDiscovery #Pharmacology | Dr. GPCR EcosystemTerry Kenakin on May 1st, 2025, for an advanced live workshop on allosteric modulators in GPCR drug discovery www.ecosystem.drgpcr.com/event-details-registration/practical-quantification-of-allosteric-modulation #GPCR #Allostery #DrugDiscovery #Pharmacology Published on March 3, 2025 Category GPCR University 🚀 New Workshop Terry Kenakin on May 1st, 2025 , for an advanced live workshop on allosteric modulators in GPCR drug Breakthroughs this week: Potentiation of GPCR signaling by ATP and sugar monophosphates; Pharmacology 





