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We demonstrate by pharmacologic inhibition of GRK2/3-mediated phosphorylation of the chemokine receptor

bona fide agonist of PAR2 that uniquely modulates PAR2-mediated cellular signaling and is a useful pharmacological

The development of new CB2-related pharmacological and genetic tools, including the first small molecule

This $60,000 grant from Diabetes Research WA will assist the Perkins' Molecular Endocrinology and Pharmacology

chaperones to improve the folding and stability of the mutant receptor is one of the most promising pharmacological

In this study Marsango et al. address two key questions in GPR84 biology and pharmacology: 1. how GPR84 ligands (Pillaiyar et al., 2018) with biased properties which can help to better elucidate the molecular pharmacology

Despite its therapeutic potential, CB2 pharmacology remains difficult to interrogate with confidence. For researchers working in cannabinoid pharmacology, inflammation, or GPCR-mediated analgesia, these

The course covers basic pharmacology in four weekly segments. Only 14 out of 20 spots remain. , 2024 | 11th Adhesion GPCR Workshop July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology

Finally, we validated A2BAR as a potential pharmacological tool in CRC, using selective antagonists,

perception, and thought, and have the activation of serotonin (5-HT) 2A receptors (5-HT2A Rs) as a main pharmacological

Here, GPR15L(25-81) and GPR15L(71-81) are used as pharmacological tool compounds to delineate the GPR15

Despite considerable advances in pharmacological treatment, HF represents a severe clinical and social

evaluate parathyroid hormone (PTH) and PTH-related protein (PTHrP) ligands and analogues for their pharmacologic

Kenakin’s latest lecture delivers a paradigm shift for pharmacologists working on drugs where in vitro future topics Access to the study group Whether you’re in hit-to-lead, lead optimization, or clinical pharmacology

provide proof of concept for the development of safer GPCR-targeting therapeutics with more directed pharmacological

Much of the understanding of psychedelic pharmacology is derived from rodent models, but most of this

The pharmacological profiles and mechanistic insights of our study provide clues for the future design

Biased pharmacological modulators provide potential therapeutic benefits, including greater pharmacodynamic

agricultural settings inspired him to train in veterinary medicine, where he was introduced to physiology and pharmacology

together, these results will benefit further investigations to determine physiological functions and pharmacological

This innovation emerged from years of foundational work in photophysics and GPCR pharmacology.

Flow Cytometry validation performed in the Oncological Pharmacology Laboratory of the University of Turin

They provide rapid and scalable assessment of pharmacological parameters.

They unlocked pharmacologically relevant insights that were previously inaccessible.

Nuclear G-protein-coupled receptors as putative novel pharmacological targets. Frontiers in pharmacology, 9, 431. https://doi.org/10.3389/fphar.2018.00431

Activation of melatonin MT2 receptors with either pharmacological concentrations of melatonin (10-100

Postdoctoral Fellow, Caron Lab Clinical Trial Associate Research Scientist/Senior Scientist I - Molecular Pharmacology

receptors (SSTs) are class A GPCRs abundantly expressed in pituitary tumors where they represent the main pharmacological

effects of O-glycosylation and tyrosine sulfation modulation on the chemokine receptors CCR1 and CCR5 pharmacology evidence proposes that O-glycosylation and sulfation are important PTMs in chemokine receptor biology and pharmacology

Postdoc Research Associate Director, Regulatory Affairs Research Scientist/Senior Scientist I - Molecular Pharmacology