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Results found for "Adam W Smith"
- 📰 GPCR Weekly News, March 25 to March 31, 2024
This week's highlight includes congrats to: Junyi Liang, Niña Caculitan, and Adam W Smith for their research
- Dr. Nicola J. Smith - Dr. GPCR Podcast
Nicola Smith, Molecular Pharmacologist, lab head, and senior lecturer at UNSW Sydney.
- Dr. GPCR Updates
w=cw8ae7XNuBdiMbjg4TeUw3rdv2qYhR4rv-bqGLmA948.eyJ1IjoiaHR0cHM6Ly9kb2kub3JnLzEwLjExMTEvYnBoLjcwMDcyIiwiciI6ImUyZGZlOTFjLTM5YzgtNDA5Yi04NTUyLWI5NjUwNGRlNzc4MyIsIm0iOiJtYWlsX2xwIiwiYyI6IjAwMDAwMDAwLTAwMDAtMDAwMC0wMDAwLTAwMDAwMDAwMDAwMCJ9
- A robust and Efficient FRET-Based Assay for Cannabinoid Receptor Ligands Discovery.
W.; Wu, Y.; Zhao, S.; Shui, W.; Li, S.; Korde, A.; Laprairie, R. B.; Stahl, E. L.; Ho, J. W.; Iyer, M. R.; Cinar, R.; Coffey, N. Chem. 2019 , 62 (1), 276–287. https://doi.org/10.1021/acs.jmedchem.8b00368 . (9) Adams, A. Martín-Fontecha, M.; Angelina, A.; Rückert, B.; Rueda-Zubiaurre, A.; Martín-Cruz, L.; Van De Veen, W. J.; Guba, W.; Alker, A.; Rufer, A. C.; Kusznir, E. A.; Huber, S.; Raposo, C.; Zirwes, E.
- Conjugation Strategies for Probe Development
W.; Santi, D. V. Long-Term Stabilization of Maleimide–Thiol Conjugates. W. Cu-Catalyzed Azide−Alkyne Cycloaddition. Chem.
- The Perils and Guardrails of Modifying Signalling Proteins in Bioassays
Shen S, Zhao C, Wu C, Sun S, Li Z, Yan W, et al. Crilly SE, Ko W, Weinberg ZY,Puthenveedu MA. Truong ME, Bilekova S, Choksi SP, Li W, Bugaj LJ, Xu K, et al. Franzen MM, Alder ML, Dreyer F, Köpp W, Buchholz MB. Wilner W. Participatory experience: the participant observer paradox.
- Fluorescence based HTS compatible ligand binding assays for dopamine D3 receptors in baculovirus preparations and live cells
W.; Högl, B.; Bainbridge, J.; Buchfuhrer, M.; Hadjigeorgiou, G.; Inoue, Y.; Manconi, M.; Oertel, W.; Ondo, W.; Winkelmann, J.; Allen, R. . https://doi.org/10.1016/j.tips.2017.10.004 . (9) Marheineke, K.; Grünewald, S.; Christie, W. Dordrecht, 2014; pp 55–74. https://doi.org/10.1007/978-94-007-7423-0_4 . (12) Yung-Chi, C.; Prusoff, W.
- VAMP2: a crucial player in the delivery of MOR to the synapse
vesicle-associated-membrane-protein-2-is-a-cargo-selective-v-snare-for-a-subset-of-gpcrs #GPCR #DrGPCR#Ecosystem Crilly, S.E., W. Wickner, W., and R. Schekman. 2008. Membrane fusion. Nat. Struct. Mol. Biol. 15:658–664.
- Maria’s Travel Blogs: ACSMEDI-EFMC Medicinal Chemistry Frontiers 2025
Terry W. Moore, was most definitely a success.
- Nanobodies: New Dimensions in GPCR Signaling Research
H., Pautsch, A., Steyaert, J., Weis, W. I., & Kobilka, B. K. (2011). C., Gmeiner, P., Steyaert, J., Weis, W. I., Garcia, K. C., Wess, J., & Kobilka, B. K. (2013).
- Applications of Fluorescent Probes in Confocal Imaging of GPCRs: From Live to Fixed Cells
Jang W, Senarath K, Feinberg G, Lu S, Lambert NA.
- Do You Believe AI Could Accelerate Drug Discovery?
Nature 630, 493–500 (2024). https://doi.org/10.1038/s41586-024-07487-w
- Ode to GPCRs
Earl W. Earl W. Earl W. Sir James W. Sir James W.
- Fluorescence Polarization in GPCR Research
Adapted from: Zhang Y, Tang H, Chen W, Zhang J.
- Unveiling GPCR Priming: The Hidden Synergy in Cellular Signalling
Stallaert, W., et al., Purinergic Receptor Transactivation by the β(2)-Adrenergic Receptor Increases
- Class B1 GPCR Dimerization: Unveiling Its Role in Receptor Function and Signaling
Guo, W., et al., Crosstalk in G protein-coupled receptors: Changes at the transmembrane homodimer interface
- From DNA day to GPCR genomics
W., & Skiniotis, G. (2023).
- Harnessing Deep Mutational Scanning for Enhanced Drug Discovery
G., Coyote-Maestas, W., & Aashish Manglik. (2024).
- Odorant receptors – a bit of smell for drug discovery
For example, OR4M1 was proposed to interfere with aberrant tau hyperphosphorylation (Zhao W. et. al 2013
- 🎄 Have Yourself a Merry Little GPCRmas! ❄ Dec 9 - 15, 2024
contributes to inflammatory joint pain Luke A Pattison , Rebecca H Rickman , Graham Ladds , Ewan St John Smith
- Decoding β-Arrestins: from Structure to function
their imbalance is linked to pathological conditions, including cancer (Gros, R. et al. 2000, Sun, W.
- 📰 GPCR Weekly News, May 20 to 26, 2024
Extracellular signal-regulated kinases – a potential pathway for GPCR-targeted drug discovery Nicola J Smith
- 📰 GPCR Weekly News, July 31 to August 6, 2023
Nichola J Smith's investigation: Gene expression of TAS1R taste receptors for cardiometabolic disease
- Chemokine receptor-targeted drug discovery: progress and challenges
the engagement of the receptor with a certain effector, thus enriching a specific signaling pathway (Smith
- Artificial intelligence – faster, smarter, cheaper GPCR drug discovery
previously established chemical space, limiting their ability to identify truly novel chemotypes”(Thomas, Smith












