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We have carried out MARTINI coarse-grained molecular dynamics simulations of SMO in POPC and in ciliary models, respectively, to study the interactions of SMO with cholesterol and other lipid molecules in the ciliary

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.; Miller, L. J. . https://doi.org/10.1016/S0304-3940(01)01568-3 . (15)      Grätz, L.; Tropmann, K.; Bresinsky, M.; Müller Nanoscale   2021 , 13 (4), 2436–2447. https://doi.org/10.1039/D0NR06737G . (17)      Müller, C.; Gleixner

patterns of GPCRs in different immune cell types, including B cells, CD4+ T cells, CD8+ T cells, natural killer

S1P5 is predominantly expressed in nervous and immune systems, regulating the egress of natural killer

Thus, increased SHH activity due to ciliary dysfunction may be required for the development of pathoetiological

.; Hillard, C. J.; Varga, Z. T.; Hess, C.; Madea, B.; Meiler, J.; Müller, C. E. G.; Millet, R.; Goossens, J.-F.; Farce, A.; Chavatte, P.; Poupaert, J. H.; Lambert, D.

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The real killer, however, is apnea—those silent pauses where oxygen saturation crashes, often missed

carbinol, which is present at high levels in some vegetables including broccoli and kale (Wang, Schoene, Milner

Updates in GPCR Research Memprot.GPCR-ModSim: Modelling and simulation of membrane proteins in a nutshell Ciliary

Read the Feature ➤ Summer Days: Appetite, Suntans, and GPCR Micro-Domains Two recent papers connect ciliary

spectral shifts deliver efficient subcellular signaling Striatal serotonin release signals reward value Ciliary

oligodendrocyte precursor cell proliferation in white matter injury via Hedgehog-independent CREB signaling Ciliary

GPCR Activation and Signaling Ubiquitylation of BBSome is required for ciliary assembly and signaling

heterogeneity of astrocyte reactivity in Alzheimer's disease GPCRs in Oncology and Immunology Context-dependent ciliary

.; Müller, C.

Molecular Insights into GPCR Function GPR161 structure uncovers the redundant role of sterol-regulated ciliary

GPCRs in Neuroscience Physiological Condition Dependent Changes in Ciliary GPCR Localization in the Brain

GPCRs in Neuroscience Physiological Condition-Dependent Changes in Ciliary GPCR Localization in the Brain

diabetic cardiomyopathy in mice GPCRs in Neuroscience Coexistence within one cell of microvillous and ciliary

Bivalent Dicovalent Ligands for the Adenosine A1 Receptor GPCRs in Cardiology, Endocrinology, and Taste Ciliary

Vertebrate cells differentially interpret ciliary and extraciliary cAMP.