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Results found for "Hillary A. Miller"
- Structural dynamics of Smoothened (SMO) in ciliary membrane and its interaction with membrane lipids
We have carried out MARTINI coarse-grained molecular dynamics simulations of SMO in POPC and in ciliary models, respectively, to study the interactions of SMO with cholesterol and other lipid molecules in the ciliary
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- Fluorescence based HTS compatible ligand binding assays for dopamine D3 receptors in baculovirus preparations and live cells
.; Miller, L. J. . https://doi.org/10.1016/S0304-3940(01)01568-3 . (15) Grätz, L.; Tropmann, K.; Bresinsky, M.; Müller Nanoscale 2021 , 13 (4), 2436–2447. https://doi.org/10.1039/D0NR06737G . (17) Müller, C.; Gleixner
- Profiling Immune Cell and Platelet Transcriptomes
patterns of GPCRs in different immune cell types, including B cells, CD4+ T cells, CD8+ T cells, natural killer
- Structural basis for receptor selectivity and inverse agonism in S1P5 receptors
S1P5 is predominantly expressed in nervous and immune systems, regulating the egress of natural killer
- Primary cilia and SHH signaling impairments in human and mouse models of Parkinson’s disease
Thus, increased SHH activity due to ciliary dysfunction may be required for the development of pathoetiological
- A robust and Efficient FRET-Based Assay for Cannabinoid Receptor Ligands Discovery.
.; Hillard, C. J.; Varga, Z. T.; Hess, C.; Madea, B.; Meiler, J.; Müller, C. E. G.; Millet, R.; Goossens, J.-F.; Farce, A.; Chavatte, P.; Poupaert, J. H.; Lambert, D.
- How to Design GPCR Drugs That Work in Vivo: Strategy, Tools, and Insights
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- Fentanyl and Xylazine: Why Breathing Fails in Overdose
The real killer, however, is apnea—those silent pauses where oxygen saturation crashes, often missed
- Therapeutic validation of an orphan G protein‐coupled receptor
carbinol, which is present at high levels in some vegetables including broccoli and kale (Wang, Schoene, Milner
- What's Going On with GPCRs?! Find Out in This Week's Update! ⦿ Nov 4 - 10, 2024
Updates in GPCR Research Memprot.GPCR-ModSim: Modelling and simulation of membrane proteins in a nutshell Ciliary
- Understanding Enzyme Inhibition In GPCR Discovery Programs
Read the Feature ➤ Summer Days: Appetite, Suntans, and GPCR Micro-Domains Two recent papers connect ciliary
- 📰 GPCR Buzz: August 5-11, 2024 | Top Highlights from DrGPCR University!
spectral shifts deliver efficient subcellular signaling Striatal serotonin release signals reward value Ciliary
- 📰 GPCR Weekly News, October 16 to 22, 2023
oligodendrocyte precursor cell proliferation in white matter injury via Hedgehog-independent CREB signaling Ciliary
- 📰 GPCR Weekly News, February 6 to 12, 2023
GPCR Activation and Signaling Ubiquitylation of BBSome is required for ciliary assembly and signaling
- 📰 GPCR Weekly News, November 6 to November 12, 2023
heterogeneity of astrocyte reactivity in Alzheimer's disease GPCRs in Oncology and Immunology Context-dependent ciliary
- 📰 GPCR Weekly News, February 5 to 11, 2024
Molecular Insights into GPCR Function GPR161 structure uncovers the redundant role of sterol-regulated ciliary
- 📰 GPCR Weekly News, February 27 to March 5, 2023
GPCRs in Neuroscience Physiological Condition Dependent Changes in Ciliary GPCR Localization in the Brain
- 📰 GPCR Weekly News, March 13 to 19, 2023
GPCRs in Neuroscience Physiological Condition-Dependent Changes in Ciliary GPCR Localization in the Brain
- 📰 GPCR Weekly News, December 18 to 31, 2023
diabetic cardiomyopathy in mice GPCRs in Neuroscience Coexistence within one cell of microvillous and ciliary
- GPCR Weekly Whirlwind: Top Receptor Highlights from Sep 30 - Oct 6, 2024!
Bivalent Dicovalent Ligands for the Adenosine A1 Receptor GPCRs in Cardiology, Endocrinology, and Taste Ciliary
- The Perils and Guardrails of Modifying Signalling Proteins in Bioassays
Vertebrate cells differentially interpret ciliary and extraciliary cAMP.











