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- TeachOpenCADD - A teaching platform for computer-aided drug design
both the theoretical as well as practical aspect of these topics, the platform addresses students and researchers
- 📰 GPCR Weekly News
Center-Related G Protein-Coupled Receptors in Antibody-Mediated Autoimmune Skin Diseases: from Basic Research Methods & Updates in GPCR Research CPGL: Prediction of Compound-Protein Interaction by Integrating Graph
- GPCR Happy Hour – Boston, Sept 2025
Our mission is simple: bridge science and industry by connecting researchers, biotech, CROs, and pharma
- Sosei Heptares Announces Antitrust Clearance of License Agreement with Neurocrine Biosciences
December 2021 "Tokyo, Japan and Cambridge, UK, 24 December 2021 – Sosei Group Corporation (“Sosei Heptares
- Radioligands vs. Fluorescent Ligands: Binding Assays
Understanding receptor-ligand interaction is key in drug discovery and biomedical research.
- Misread the Curve, Misjudge the Drug: Rethinking Antagonism in GPCR Pharmacology
Why now: GPCR research is accelerating—and the projects that succeed will be those built on clear, accurate
- Platelets in the NETworks interweaving inflammation and thrombosis
Research over the past years has provided a substantial body of evidence demonstrating that platelets
- Do You Believe AI Could Accelerate Drug Discovery?
screening and large-scale data analysis, paving the way for a new era in precision medicine and medical research
- Involvement of various chemokine/chemokine receptor axes in trafficking and oriented locomotion ...
Despite intensive research, a known treatment for MS disease yet to be introduced.
- How GPCR Collaboration Built an Innovation Engine
Why This Matters GPCR research demands integration — pharmacology, structural biology, signaling pathways
- Phenylalanine 193 in Extracellular Loop 2 of the β 2-Adrenergic Receptor Coordinates β-Arrestin ...
Despite decades of research on the signaling consequences of molecule-receptor interactions, conformational
- Sosei Heptares Enters Antibody Discovery Agreement with Twist Bioscience to Discover and Develop ...
platform to generate novel antibody leads to disease-relevant GPCR targets Tokyo, Japan and Cambridge, UK
- Deficiency of β-arrestin2 alleviates apoptosis through GRP78-ATF6-CHOP signaling pathway in ...
This research further clarified the underlying role of β-arrestin2 and provided an experimental foundation
- GPCR Binding Affinity Experiments: Interpreting Data With Confidence as We Head Into 2026
In Episode 3 of 3 of our series with Celtarys Research , leaders from academia and biotech unpack what
- When the Islet Lit Up: Advancing GPCR Imaging in Native Tissue
conversation is part of a three episode series produced in collaboration with our partners at Celtarys Research
- The Truth About GPCR Product Launches: Years in the Making
behind-the-scenes access to GPCR innovators, exclusive deep-dives, and practical tools to accelerate your research
- Unveiling GPCR Priming: The Hidden Synergy in Cellular Signalling
In conclusion, GPCR priming represents a compelling area of research that promises to deepen our understanding
- Decoding Schild Analysis: The Pharmacologist’s Lens on Competitive Antagonism
It encourages skepticism—forcing researchers to prove competition before quantifying it.
- Artificial intelligence – faster, smarter, cheaper GPCR drug discovery
cannot adequately predict protein structure (Jumper et al., 2021) ); 3) the same limitation holds when searching Automated tools for researchers: AI solutions which bring together theoretical, computational, and experimental Instead, it complements and assists researchers in the GPCR drug discovery process.
- Targeting GPCRs in the CNS: Advances in Drug Discovery Strategies
More research into the endocannabinoid system (ECS) will let us access these GPCRs in a safer manner
- Ode to GPCRs
Therefore, the presentation of 10 or more Nobel prizes highlights the importance of research work on the primary physiological and chemical visual processes in the eye.[7–11] Through Nobel prize-winning research Prize in Physiology or Medicine went to Eric Richard Kandel, Arvid Carlsson, and Paul Greengard for research Therefore, we envision that this field will continue to produce high-impact research work that will garner
- How to Avoid the Most Common Gaps in Your Biotech Pitch
But your audience isn’t evaluating you as a researcher.
- Decoding GPCR Function: The Role of Mutagenesis in Rational Drug Discovery
Additionally, deep mutational scanning can generate large-scale datasets, allowing researchers to determine
- Why Biotech Fundraising Fails Due to Intellectual Property Gaps
Patents focused on one indication, while the business story targets another 👉 Claims that protect research
- GPCRs are not simple on-off switches: deep dive into GPCR-ligand interactions
GPCRs functional selectivity Recent research has revealed a more intricate understanding of GPCR behavior
- Targeting Intracellular Allosteric Sites in GPCRs
Recent advances in structural biology have allowed researchers to visualize the binding of allosteric
- The Five Traps of Ignoring Kinetics
At equilibrium, these effects cancel. But kinetics unmasks them.
- Overview of adhesion GPCRs self-activation
knowing the factors that determine the selectivity of coupling represents a very interesting area of research
- Glyco-sulfo hotspots in the chemokine receptor system
Further research will be needed to boost our understanding on the dynamics and biological relevance of















