Search Results

Hello GPCR Community, Stay up-to-date with the latest GPCR research, including breakthrough studies, top researchers to explore the latest advances in designing precise GPCR-targeted drugs, including the Research Services Agreement with Pfizer on Targeted Protein Degradation Modalities A quick revision July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology GPCR Jobs HIGHLIGHT Research mechanosensing   Postdoctoral Position Postdoctoral research position Senior or Lead Researcher   GPCR

Sandra Berndt talk about new structural perspectives in GPCR-mediated Src family kinase activation. Register here (FREE) https://www.ecosystem.drgpcr.com/dr-gpcr-virtual-cafe #drgpcr #gpcr #virtualcafe

Autoimmune Diseases "The chemokine receptor CXCR3 is a seven-transmembrane G-protein-coupled receptor (GPCR Read more at the source #DrGPCR #GPCR #IndustryNews

orphan and constitutively active receptor belonging to the superfamily of G-Protein Coupled Receptors (GPCRs Read more at the source #DrGPCR #GPCR #IndustryNews

Dear GPCR Community, Before diving into this week's news, prepare for an incredible learning journey! This week's highlight includes congrats to: Madison Walker , Benjamin Myers , et al., for their research Research Probing PAC1 receptor activation across species with an engineered sensor A Multi-Angle Approach Jobs Postdoc in GPCR mechanosensing   Postdoctoral Position Postdoctoral research position Senior or Lead Researcher   Senior Scientist, Cryo-Electron Microscopy   Postdoctoral Research Associate Become

Here, 33 neuropeptide precursors and 48 putative neuropeptide G protein-coupled receptor (GPCR) genes This research provides more knowledge on neuropeptide systems and sets the groundwork for the creation Read more at the source #DrGPCR #GPCR #IndustryNews

Read more at the source #DrGPCR #GPCR #IndustryNews

scoring protective hits included the complement C3a receptor (C3aR), a G-protein coupled receptor (GPCR Read more at the source #DrGPCR #GPCR #IndustryNews

advances in the field of pharmacological CVD treatments, particularly in the field of heart failure (HF) research Thus, identifying novel molecular targets for developing HF therapeutics remains a key research focus A recent focus on GPCR intracellular-regulating proteins such as GPCR kinases (GRKs) has uncovered GRK2 and maladaptive pathology, and summarizes the ongoing and future research for targeting this critical Read more at the source #DrGPCR #GPCR #IndustryNews

FAB6695 and scrutinize the apparent ACKR1 expression in BM macrophages" Read more at the source #DrGPCR #GPCR

A much smaller conformational change of helix VI upon activation than previously solved class A GPCR-Gi Thus, our data deepen the understanding of cholesterol modulation in GPCR (G protein-coupled receptor Read more at the source #DrGPCR #GPCR #IndustryNews

Imagine you're navigating a vast terrain—not on foot, but through the shape-shifting world of GPCRs.

August 2022 Addex and Indivior Extend GABAB Positive Allosteric Modulator Research Collaboration for US $900,000) of additional research funding. compounds for Charcot-Marie-Tooth type 1A neuropathy (CMT1A) and pain. " Read more at the source #DrGPCR #GPCR

Matthew T Eddy and his team's research on A2A adenosine receptor activation by G protein and mutations Research Modulating signalling lifetime to optimise a prototypical animal opsin for optogenetic applications drug research Tectonic Therapeutic Announces Start of First Clinical Program for GPCR-Targeted Biologic biomarker expert NEW Postdoctoral Fellow NEW Scientific Assistant Scientist Lead Researcher Post-Doctoral GPCR Ecosystem

March 2022 ERNEST has established an Emergency Fund for Ukrainian researchers. "General Eligibility Researchers affiliated to any legal entity in Ukraine (for example, schools and universities, research centers, governmental institutions, or private companies) Deadlines Start of the Our scientific perspective is broad, and we are happy to consider any research proposals from those in Read more at the source #DrGPCR #GPCR #IndustryNews

Read more at the source #DrGPCR #GPCR #IndustryNews

GPCR on the 24th of June! This time, the GPCRdb team ( Dr. David Gloriam , Dr. Reserve your spot for free at: https://www.ecosystem.drgpcr.com/dr-gpcr-virtual-cafe/ #GPCR #GPCRs #DrGPCR

essential to maintaining proper cardiac output and circulation, is regulated by G protein-coupled receptor (GPCR Read more at the source #DrGPCR #GPCR #IndustryNews

representative proteins that regulate the transduction and trafficking of G protein-coupled receptor (GPCR Read more at the source #DrGPCR #GPCR #IndustryNews

desire for additional approaches to mental health care, incremental progress in basic and clinical research Read more at the source #DrGPCR #GPCR #IndustryNews

GPCR News.   Elevate your pharmacology expertise. Unlock "Pharmacologic Models" now

microscopy (cryo-EM) is used extensively to determine structures of activated G protein-coupled receptors (GPCRs However, applying it to GPCRs without signaling proteins remains challenging because most receptors lack In GPCR crystallography, inserting a fusion protein between transmembrane helices 5 and 6 is a highly The fusion strategies explored here are likely applicable to cryo-EM interrogation of other GPCRs and Read more at the source #DrGPCR #GPCR #IndustryNews

January 2022 Exscientia and Sanofi Establish Strategic Research Collaboration to Develop AI-driven Pipeline capabilities and personalised medicine platform from target identification through patient selection Research royalties PARIS & OXFORD, England & BOSTON--Sanofi and Exscientia announced today a groundbreaking research Read more at the source #DrGPCR #GPCR #IndustryNews

Originally, β-arrestins were identified for their contribution to GPCR desensitization to agonist-mediated However, current investigations have now recognized that in addition to GPCR arresting (hence the name Read more at the source #DrGPCR #GPCR #IndustryNews

in Sapap3 knockout mice Methods & Updates in GPCR Research Genome-wide identification of 769 G protein-coupled Project Ambrosia lands $16m to ‘improve on existing GLP-1 drugs’ Opening Ceremony of Xuzhou Zhongshu Research July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology GPCR Jobs NEW Research Associate Postdoc in GPCR mechanosensing   Postdoctoral Position Postdoctoral research position Senior or Lead Researcher   Become a Premium Member!

Read more at the source #DrGPCR #GPCR #IndustryNews

Previously, we identified potent positive crosstalk between insulin/IGF-1 receptors and G protein-coupled (GPCR Here, we show that a combination of insulin and the GPCR agonist neurotensin induced rapid activation Read more at the source #DrGPCR #GPCR #IndustryNews

pro-inflammatory neutrophil response, signaling downstream of an agonist-activated G protein-coupled receptor (GPCR Among the family of GPCR kinases (GRKs) that regulate receptor phosphorylation and signaling termination analysis of subcellular fractions revealed a cytosolic localization. " Read more at the source #DrGPCR #GPCR

October 2022 "Visual phototransduction is the most extensively studied G protein-coupled receptor (GPCR Read more at the source #DrGPCR #GPCR #IndustryNews

August 2022 "Background: Activation of signaling effectors by G-protein coupled receptors (GPCRs) depends participate in a molecular mechanism to trigger β-arrestin recruitment. " Read more at the source #DrGPCR #GPCR