Search Results
Results found for "GPCR research community"
- Diversification of PAR signaling through receptor crosstalk
Read more at the source #DrGPCR #GPCR #IndustryNews
- đź“° GPCR Weekly News, January 30 to February 5, 2023
Keep up-to-date with the latest research and advancements in the field with our convenient, weekly news Methods & Updates in GPCR Research Deep-Learning-Enhanced Diffusion Imaging Assay for Resolving Local-Density Bioinformatics/Data Science at Department of Drug Design and Pharmacology Scientist/Senior Scientist (Research Assistant Research Fellow - School of Physics and Astronomy Postdoctoral Research Associate (Fixed Term GPCR Ecosystem
- Unlock the Hidden Lives of Receptors – Are You Ready?
Imagine you're navigating a vast terrain—not on foot, but through the shape-shifting world of GPCRs.
- đź“° GPCR Weekly News, February 27 to March 5, 2023
Hello Readersđź‘‹, GPCR weekly newsletter is here! GPCR Symposium event held on March 24th. GPCRs in Neuroscience Physiological Condition Dependent Changes in Ciliary GPCR Localization in the Brain Methods & Updates in GPCR Research Time- and cost-efficient bacterial expression and purification of GPCR Ecosystem
- Discovery and In Vivo Evaluation of ACT-660602: A Potent and Selective Antagonist of the Chemokine..
Autoimmune Diseases "The chemokine receptor CXCR3 is a seven-transmembrane G-protein-coupled receptor (GPCR Read more at the source #DrGPCR #GPCR #IndustryNews
- 🎧Episode 85 of the Dr. GPCR podcast is here!
GPCR podcast is here! 🎧Hear Dr. GPCR Ecosystem membership or listen wherever you get your podcast for free.
- G protein-coupled receptor 21 in macrophages: An in vitro study
orphan and constitutively active receptor belonging to the superfamily of G-Protein Coupled Receptors (GPCRs Read more at the source #DrGPCR #GPCR #IndustryNews
- Comparative study of neuropeptide signaling systems in Hemiptera
Here, 33 neuropeptide precursors and 48 putative neuropeptide G protein-coupled receptor (GPCR) genes This research provides more knowledge on neuropeptide systems and sets the groundwork for the creation Read more at the source #DrGPCR #GPCR #IndustryNews
- Genome-scale CRISPR screening reveals that C3aR signaling is critical for rapid capture of fungi...
scoring protective hits included the complement C3a receptor (C3aR), a G-protein coupled receptor (GPCR Read more at the source #DrGPCR #GPCR #IndustryNews
- New structural perspectives in G protein-coupled receptor-mediated Src family kinase activation
Sandra Berndt talk about new structural perspectives in GPCR-mediated Src family kinase activation. Register here (FREE) https://www.ecosystem.drgpcr.com/dr-gpcr-virtual-cafe #drgpcr #gpcr #virtualcafe
- GRK2 in cardiovascular disease and its potential as a therapeutic target
advances in the field of pharmacological CVD treatments, particularly in the field of heart failure (HF) research Thus, identifying novel molecular targets for developing HF therapeutics remains a key research focus A recent focus on GPCR intracellular-regulating proteins such as GPCR kinases (GRKs) has uncovered GRK2 and maladaptive pathology, and summarizes the ongoing and future research for targeting this critical Read more at the source #DrGPCR #GPCR #IndustryNews
- GPCR Updates: Celebrating Breakthroughs, New Course Launches Soon, and Exclusive Discounts! | Aug 26 - Sep 1, 2024
Hello GPCR Community, Stay up-to-date with the latest GPCR research, including breakthrough studies, top researchers to explore the latest advances in designing precise GPCR-targeted drugs, including the Research Services Agreement with Pfizer on Targeted Protein Degradation Modalities A quick revision July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology GPCR Jobs HIGHLIGHT Research mechanosensing  Postdoctoral Position Postdoctoral research position Senior or Lead Researcher  GPCR
- Activation of the human chemokine receptor CX3CR1 regulated by cholesterol
A much smaller conformational change of helix VI upon activation than previously solved class A GPCR-Gi Thus, our data deepen the understanding of cholesterol modulation in GPCR (G protein-coupled receptor Read more at the source #DrGPCR #GPCR #IndustryNews
- Murine bone marrow macrophages and human monocytes do not express atypical chemokine receptor 1
FAB6695 and scrutinize the apparent ACKR1 expression in BM macrophages" Read more at the source #DrGPCR #GPCR
- đź“° GPCR Weekly Buzz: Exciting Schedule Shifts for Principles of Pharmacology I & II | August 12-18, 2024
Dear GPCR Community, Before diving into this week's news, prepare for an incredible learning journey! This week's highlight includes congrats to: Madison Walker , Benjamin Myers , et al., for their research Research Probing PAC1 receptor activation across species with an engineered sensor A Multi-Angle Approach Jobs Postdoc in GPCR mechanosensing  Postdoctoral Position Postdoctoral research position Senior or Lead Researcher  Senior Scientist, Cryo-Electron Microscopy  Postdoctoral Research Associate Become
- Pharmacologic Models
GPCR News. Â Elevate your pharmacology expertise. Unlock "Pharmacologic Models" now
- Dual loss of regulator of G protein signaling 2 and 5 exacerbates ventricular myocyte arrhythmias...
essential to maintaining proper cardiac output and circulation, is regulated by G protein-coupled receptor (GPCR Read more at the source #DrGPCR #GPCR #IndustryNews
- Dr. GPCR Virtual Cafe with Matthew Eddy - New date!
GPCR Virtual Cafe session with Dr. Matthew E. on Friday, October 7th at 1 PM ET. Don't miss the chance to listen to his latest research on the field.
- Arginine 125 Is an Essential Residue for the Function of MRAP2
Read more at the source #DrGPCR #GPCR #IndustryNews
- Fusion protein strategies for cryo-EM study of G protein-coupled receptors
microscopy (cryo-EM) is used extensively to determine structures of activated G protein-coupled receptors (GPCRs However, applying it to GPCRs without signaling proteins remains challenging because most receptors lack In GPCR crystallography, inserting a fusion protein between transmembrane helices 5 and 6 is a highly The fusion strategies explored here are likely applicable to cryo-EM interrogation of other GPCRs and Read more at the source #DrGPCR #GPCR #IndustryNews
- G protein-coupled receptor kinase type 2 and β-arrestin2: Key players in immune cell functions...
representative proteins that regulate the transduction and trafficking of G protein-coupled receptor (GPCR Read more at the source #DrGPCR #GPCR #IndustryNews
- Molecular insights into psychedelic drug action
desire for additional approaches to mental health care, incremental progress in basic and clinical research Read more at the source #DrGPCR #GPCR #IndustryNews
- Meet Peter McNamara, Ph.D., Tectonic’s SVP, Head of Research
December 2021 "Meet Peter McNamara, Ph.D., Tectonic’s SVP, Head of Research. Peter joined Tectonic to help chart new territory in GPCR science. Read more at the source #DrGPCR #GPCR #IndustryNews
- Deciphering the signaling mechanisms of β-arrestin1 and β-arrestin2 in regulation of cancer cell...
Originally, β-arrestins were identified for their contribution to GPCR desensitization to agonist-mediated However, current investigations have now recognized that in addition to GPCR arresting (hence the name Read more at the source #DrGPCR #GPCR #IndustryNews
- GRK2 selectively attenuates the neutrophil NADPH-oxidase response triggered by β-arrestin recruiting
pro-inflammatory neutrophil response, signaling downstream of an agonist-activated G protein-coupled receptor (GPCR Among the family of GPCR kinases (GRKs) that regulate receptor phosphorylation and signaling termination analysis of subcellular fractions revealed a cytosolic localization. " Read more at the source #DrGPCR #GPCR
- Opposite Effects of Src Family Kinases on YAP and ERK Activation in Pancreatic Cancer Cells...
Previously, we identified potent positive crosstalk between insulin/IGF-1 receptors and G protein-coupled (GPCR Here, we show that a combination of insulin and the GPCR agonist neurotensin induced rapid activation Read more at the source #DrGPCR #GPCR #IndustryNews
- GASP1 enhances malignant phenotypes of breast cancer cells and decreases their response to...
Read more at the source #DrGPCR #GPCR #IndustryNews
- Molecular creativity in drug discovery
Innovative Approaches in GPCR Drug Discovery: Designing Precise Solutions for GPCR Challenges. GPCR Podcast: Leadership, Impact, and GPCR Signaling with Dr. GPCR evolved from a grassroots effort to a global force in GPCR science—one rooted in connection, sustainability The pace of GPCR innovation is accelerating. Access this week’s full Premium Edition here ➤ Voice of the Community “Thank you for bringing this course
- Structural view of G protein-coupled receptor signaling in the retinal rod outer segment
October 2022 "Visual phototransduction is the most extensively studied G protein-coupled receptor (GPCR Read more at the source #DrGPCR #GPCR #IndustryNews
- The NPXXY Motif Regulates β-Arrestin Recruitment by the CB1 Cannabinoid Receptor
August 2022 "Background: Activation of signaling effectors by G-protein coupled receptors (GPCRs) depends participate in a molecular mechanism to trigger β-arrestin recruitment. " Read more at the source #DrGPCR #GPCR








