Search Results

development of databases supporting medical research ‘Define your own success’: Duke leaders talk success, failure

GPCRs in Oncology and Immunology A GPCR checkpoint drives CD8+ T cell dysfunction and immunotherapy failure

and Immunology The GPCR-Gαs-PKA signaling axis promotes T cell dysfunction and cancer immunotherapy failure

Immunology and Oncology The GPCR–Gαs–PKA signaling axis promotes T cell dysfunction and cancer immunotherapy failure

GPCRs in Cardiology, Endocrinology, and Taste Targeting G Protein-Coupled Receptors for Heart Failure

autoantibodies: Associations with cardiac markers, histology, and function in human non-ischaemic heart failure

Taste α1-Adrenergic Receptors: Insights into Potential Therapeutic Opportunities for COVID-19, Heart Failure

autoantibodies: Associations with cardiac markers, histology, and function in human non-ischaemic heart failure

Treatment of cells with YM failed to inhibit signaling by these PM-restricted αqQ209L.

β-arrestin2 play multiple roles in the pathological mechanisms of a wide range of diseases including heart failure

On the contrary, in M2 cells, octreotide failed to internalize both receptors whereas pasireotide promoted

with MOR: morphine adjusted its pose by continuously flipping deeper into the pocket, whereas naloxone failed

interactions at the plasma membrane, PTHrP1-141 triggers sustained cAMP signaling from the plasma membrane and fails

In fact, it is often costly, frustrating, and tortuous—and more often than not it ends in failure.

HLGR2 RNAi led to a low pupation rate (45.00%), body malformation, abnormal wing expansion, failed cuticle

Many cause receptor misfolding and failure to reach the cell surface.