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Samuel Hoare on Advanced data analysis for GPCR pharmacology, which will be held on Thursdays between Terry Kenakin’s Applying Pharmacology to Drug Discovery course. Continue to increase your knowledge of Pharmacology by joining this practical approach class today. Industry News Monash University pharmaceutical scientists honoured in NHMRC Research Excellence Awards Re-election of its Board and Executive Management Team and the Approval of Change of Company Name to Nxera Pharma

University We successfully started our Dr.GPCR University workshop, 'Advanced Data Analysis for GPCR Pharmacology Initiation of Phase 1 Clinical Study Evaluating Effects of NBI-1117567 in Healthy Adults Crinetics Pharmaceuticals Reports First Quarter 2024 Financial Results and Provides Business Update Nxera Pharma Operational Highlights and Consolidated Results for the First Quarter 2024 Crinetics Pharmaceuticals To Present Advancements 2026 GPCR Jobs Post Doctoral Fellow Postdoc Position Principal Scientist, In vitro Pharmacology Senior

GPCR University Course, ‘Applying Pharmacology to Drug Discovery,’ led by Dr. Research GPCR Events, Meetings, and Webinars March 13 - 15 | Biologics 2024 March 13 - 15 | 9th German Pharm-Tox , 2024 | 11th Adhesion GPCR Workshop July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology Research Unit Postdoctoral Scholar – Synaptic physiology, optical imaging, substance use disorder, pharmacology Research Fellow Postdoctoral Fellow – Molecular Pharmacology of Feeding Behavior Director of Laboratory

GPCR University Last week marked the beginning of our first Dr.GPCR University course, 'Applying Pharmacology coupled receptor-mediated vasocontraction in rat coronary arteries GPCRs involved in metabolic diseases: pharmacotherapeutic Board of Directors GPCR Events, Meetings, and Webinars February 20, 2024 | Career Opportunities in Pharmacology and Drug Discovery March 13 - 15 | 9th German Pharm-Tox Summit March 23 - 24, 2024 | Ligand Recognition , 2024 | 11th Adhesion GPCR Workshop July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology

Pharmacological characterization of novel small molecule agonists and antagonists for the orphan receptor Multiple Myeloma Behind Friday's $161M IPO: A star scientist, GPCR drug discovery and a plan to challenge pharma (June 4 - 8, 2023). 2023 Molecular Pharmacology (GRS) Seminar GRC. (June 10 - 11, 2023). (June 11 - 16, 2023). 19th World Congress of Basic & Clinical Pharmacology 2023. PhD student at Department of Drug Design and Pharmacology Software / database development postdoc at

Celebrating Excellence:   Patrick Sexton  and Arthur Christopoulos  Named Among Top 1% of Scientists in Pharmacology Pfleger ,  Peter J McCormick , Cristina Salmerón ,   Paul A Insel PGxDB: an interactive web-platform for pharmacogenomics novo antibodies look more like drugs  GPCR Events, Meetings, and Webinars December 10 - 12, 2024 | Pharmacology to GPCR Drug Discovery March 12 - 14, 2025 | NextGen Biomed 2025 March 25 - 28, 2025 | 10th German Pharm-Tox Research Associate - Professor Graeme Milligan Postdoc in Molecular Pharmacology - The Hauser Group

with Domain Therapeutics and Université de Montréal for GPCR-Targeted Drug Discovery "Apr.19.2022 Ono Pharmaceutical

GPCR University course, 'Applying Pharmacology to Drug Discovery,' led by Dr. and more Nanobody-Mediated Dualsteric Engagement of the Angiotensin Receptor Broadens Biased Ligand Pharmacology Pharmacological characterization and radiolabeling of VUF15485, a high-affinity small-molecule agonist and Drug Discovery March 13 - 15 | 9th German Pharm-Tox Summit March 23 - 24, 2024 | Ligand Recognition 2026 GPCR Jobs NEW Research Fellow NEW  Postdoctoral Fellow – Molecular Pharmacology of Feeding Behavior

17th, 2024 Industry News Centessa Launches Phase 2 Trial of ORX750 for Narcolepsy and IH Crinetics Pharmaceuticals to GPCR Drug Discovery March 12 - 14, 2025 | NextGen Biomed 2025 March 25 - 28, 2025 | 10th German Pharm-Tox | BIO International Convention 2025 July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology Principal Scientist, Medicinal Chemistry PhD fellowship in GPCR mechanosensing Senior Scientist, GPCR Pharmacology Research Associate - Professor Graeme Milligan Postdoc in Molecular Pharmacology - The Hauser Group

July 2022 "Not even a PIPE financing could save X4 Pharmaceuticals from enacting layoffs and trimming

GPCR University We're thrilled to share that all spots for the Applying Pharmacology to Drug Discovery Exhibition February 11 - 14, 2024 | 2024 BPS Annual Meeting NEW February 20, 2024 | Career Opportunities in Pharmacology and Drug Discovery March 13 - 15 | 9th German Pharm-Tox Summit March 23 - 24, 2024 | Ligand Recognition , 2024 | 11th Adhesion GPCR Workshop July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology

GPCR University course, Applying Pharmacology to Drug Discovery, led by Dr. The course covers basic pharmacology in four weekly segments and is open to all with a free site membership Conference and Exhibition February 11 - 14, 2024 | 2024 BPS Annual Meeting NEW March 13 - 15 | 9th German Pharm-Tox , 2024 | 11th Adhesion GPCR Workshop July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology

June 2022 "CRN04894 Selected for Oral Presentation SAN DIEGO, June 8, 2022 — Crinetics Pharmaceuticals

GPCR University This week marks the beginning of our first Dr.GPCR University course, 'Applying Pharmacology Webinars February 11 - 14, 2024 | 2024 BPS Annual Meeting February 20, 2024 | Career Opportunities in Pharmacology and Drug Discovery March 13 - 15 | 9th German Pharm-Tox Summit March 23 - 24, 2024 | Ligand Recognition , 2024 | 11th Adhesion GPCR Workshop July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology

Trevena Announces Submission of New Drug Application in China for OLINVYK® by its Partner Jiangsu Nhwa Pharmaceutical The NDA was submitted by Trevena’s partner, Jiangsu Nhwa Pharmaceutical, and follows completion by Nhwa

Pharmacological chaperones are cell-permeant small molecules that engage nascent mutant GPCRs in the Therefore, CAN1404 acts as a pharmacological chaperone and can rescue cell surface expression and function effects of genetic mutations on GPCR function and provide a proof of therapeutic principle for FSHR pharmacological

GPCRs Are Optimal Regulators of Complex Biological Systems and Orchestrate the Interface between Health and Disease GPCRs arguably represent the most effective current therapeutic targets for a plethora of diseases. GPCRs also possess a pivotal role in the regulation of the physiological balance between healthy and pathological conditions; thus, their importance in systems biology cannot be underestimated. The molecular diversity of GPCR signaling systems is likely to be closely associated with disease-associated changes in organismal tissue complexity and compartmentalization, thus enabling a nuanced GPCR-based capacity to interdict multiple disease pathomechanisms at a systemic level. GPCRs have been long considered as controllers of communication between tissues and cells. This communication involves the ligand-mediated control of cell surface receptors that then direct their stimuli to impact cell physiology. Given the tremendous success of GPCRs as therapeutic targets, considerable focus has been placed on the ability of these therapeutics to modulate diseases by acting at cell surface receptors. In the past decade, however, attention has focused upon how stable multiprotein GPCR superstructures, termed receptorsomes, both at the cell surface membrane and in the intracellular domain dictate and condition long-term GPCR activities associated with the regulation of protein expression patterns, cellular stress responses and DNA integrity management. The ability of these receptorsomes (often in the absence of typical cell surface ligands) to control complex cellular activities implicates them as key controllers of the functional balance between health and disease. A greater understanding of this function of GPCRs is likely to significantly augment our ability to further employ these proteins in a multitude of diseases. Read full article

what they weren’t built for, JB’s group engineered fluorescent ligands based on known GLP-1 and GIP pharmacology They’re team problems — the kind that require chemistry, physiology, pharmacology, structural biology

where receptor trafficking, spatial dynamics, and context-dependent signaling significantly influence pharmacology for Modern Screening Needs Radioligand binding assays have historically been the standard for GPCR pharmacology , preserving receptor conformation, trafficking, and native membrane context—key variables for GPCR pharmacology For teams working in GPCR pharmacology or cannabinoid research, these tools accelerate hit validation

agricultural settings inspired him to train in veterinary medicine, where he was introduced to physiology and pharmacology

Upcoming events:  GPCR-TDD Europe; Pharmacology 2026. Researchers navigating complex datasets, balancing innovation with assay rigor, or working across chemistry–pharmacology–physiology GPCR scientists, translational pharmacologists, biotech discovery teams, and decision-makers who need

What emerged wasn’t just another pharmacology group — it became a collaborative engine for GPCR discovery Turning Silos into Systems The early 2000s were not kind to exploratory pharmacology. But at Monash Institute of Pharmaceutical Sciences, a different idea took root: what if collaboration Why This Matters GPCR research demands integration — pharmacology, structural biology, signaling pathways

Welcome GPCR Fans, Most pharmacologists are trained to chase targets. Upcoming events:  Global GPCR summits and pharmacology forums shaping 2026 priorities. Innovation : Her lab model at Monash is shaping the next generation of GPCR scientists. 👉 Dive into spatial pharmacology GPCR scientists, translational pharmacologists, biotech drug discovery teams, and decision-makers who

the chemical matter  interacting with that target lacks the right properties to produce meaningful pharmacology In this lesson, you’ll gain: A strategic view of how chemical scaffolds shape pharmacologic outcomes It was early structure-based pharmacology. Dr. They are mainstream pharmacology. Advances in formulation and delivery have overcome earlier pharmacokinetic limitations.

GPCRs demanded something different: the integration of modeling, medicinal chemistry, and pharmacology Pharmacologists know they aren’t being oversold. A pharmacologist who understands docking, or a modeler who knows assay constraints, will collaborate

This innovation emerged from years of foundational work in photophysics and GPCR pharmacology.

Allosteric GPCR Binding Sites and Their Ligandability Potential Today, we started the Principles of Pharmacology Emerging Voices in GPCR Biology in Special Issue of Molecular Pharmacology GPCR Events, Meetings, and GPCRs-Targeted Drug Discovery Summit Europe July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology GPCR Jobs Scientist I Cell Biology - Tectonic Therapeutic Senior Scientist, GPCR Pharmacology Research Associate - Professor Graeme Milligan Postdoc in Molecular Pharmacology - The Hauser Group Postdoctoral

yes—but also a deep partnership with GPCR legend Terry Kenakin to bridge industry credibility with pharmacological That opened the door to something rare in functional pharmacology: plate-based GPCR internalization tracking internalization of endogenous GLP-1 receptors in rat beta cells—with no overexpression, no imaging, and no pharmacological

FRET-based technologies by providing high-performance fluorescent ligands designed specifically for pharmacological

Biomed Pharmacother. 2018 Feb;98:222-232. doi: 10.1016/j.biopha.2017.12.056 Azam S, Haque ME, Jakaria