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He also discovered and championed a novel prostaglandin EP4 drug candidate for development.

properties of these new ligands are deemed exceptional, a lead optimization is realized and its therapeutic development

Robert Laprairie is an Associate Professor and the Saskatchewan Research Chair in Drug Discovery and Development

affinity experiments are interpreted—and how those interpretations quietly shape SAR, lead selection, and development Every week, our team curates the most important developments so you never miss a breakthrough, opportunity

They also explored the possibility of developing an ecosystem for the GPCR University. Developing a Research Ecosystem at GPCR University Yamina and Claudia discussed developing an ecosystem

His lab focuses on developing and innovating technologies to solve broad questions in pharmacology, with

A large component of his work is centered around dysregulated signaling in cancer and the development

information on dysregulated signaling circuitries and individual genomic and molecular alterations to develop

medicinal chemist in Italy, followed by a Ph.D. in computational medicinal chemistry, during which she developed

We have developed an array of fluorescent biosensors to map kinase activity in living cells and are exploring

(MFI): a reliable, self-sustaining computational chemistry service provider, developing its own software

Alice Ting developing programmable receptors for molecular sensing and controlling cellular behaviour

Yekkirala shares the pivotal moments that transformed him from a curious PhD student into a GPCR drug developer scientists interested in translational innovation Biotech investors and strategic leaders seeking new drug development

Get it wrong, and the best molecule on paper stalls in development.

Pivoting: Redefining the Pain Research Playbook Looking ahead, Serafini’s vision is bold: build a lab that develops He aspires to become a physician-scientist, with a focus on translational in vitro and in vivo model development Other academic interests of his include studying pharmaceutical finance & healthcare administration and developing

She developed expertise over the past two decades studying structure/function relationships of GPCRs

Her research centers on developing nanobody-ligand conjugates to target GPCRs, with a focus on receptors

He has developed novel tools and methodologies to study fungal GPCRs which allowed the determination

She is an internationally recognized biophysicist for her contributions in developing constrained molecular

co-founder of Heptares Therapeutics , now called Sosei Heptares , a GPCR-focused drug discovery and development

He has developed innovative methods for in-cellulo measurement of protein-protein interactions, receptor

Brian has contributed to the discovery or development of 5 marketed drugs through his work spanning molecular

Brian has contributed to the discovery or development of 5 marketed drugs through his work spanning molecular

Aaron has a proven track record as a biologics leader as he led teams to discover and develop novel first-in-class

Pydi's laboratory is to develop GPCR-based drugs for the treatment of obesity and Type 2 Diabetes (T2D

Here’s how we add value: Bridge early discovery to development: transform receptor concepts into validated Learn how to apply GPCR concepts and data to real-world research and development.

deciphering of cellular and organ functions, which require individual adhesion GPCRs, and extends to the development

The ultimate goal of Adriano’s research is to target novel aspects of GPCR signaling for therapeutic development

Professor Pfleger has developed extensive expertise in profiling receptor binding and function at the

Lefkowitz, where his research focused on biased agonism, with the development of approaches to quantify