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Results found for "Shane Wright"
- Neurocrine Biosciences Presents Data on Treatment of Adolescent Patients with Classic Congenital ...
These data will be shared as an oral presentation by Ron S.
- 📰 GPCR Weekly News, January 29 to February 4, 2024
We will also have a poster session in breakout rooms on Zoom; if you are interested in sharing your work You'll share your contributor articles with the community, stay updated with GPCR literature, join a
- AlphaFold’s Breakthrough in GPCR Research: Revolutionizing Discovery, Yet Awaiting Experimental Proof
The AlphaFold-predicted models revealed distinct ligand-binding site shapes, enabling the prioritization
- GPCR Happy Hour – Boston, Sept 2025
chance to stand shoulder-to-shoulder with peers from across the globe and the Boston biotech scene, to share
- A Model for the Signal Initiation Complex Between Arrestin-3 and the Src Family Kinase Fgr
We report that arrestin-3 modulates Fgr activity with a hallmark bell-shaped concentration-dependence
- Co-activation of GPCRs facilitate GIRK-dependent current
KEY POINTS: Inhibitory D2 and GABAB receptors modulate dopamine neuron activity through shared G protein-coupled
- β-arrestin1 promotes tauopathy by transducing GPCR signaling, disrupting microtubules and autophagy
GPCRs share a common mechanism of action via the β-arrestin scaffolding signaling complexes, which not
- Canonical chemokine receptors as scavenging “decoys”
dampens the inflammatory response when needed; and it may interfere with other chemokine receptors which share
- Functional Characterization of the Venus Flytrap Domain of the Human TAS1R2 Sweet Taste Receptor
The TAS1R2 and TAS1R3 subunits are members of a small family of class C GPCRs whose members share the
- How GPCR Spatial Signaling Sparked a Scientific Journey
She went from reluctant intern to global researcher shaping how we understand GPCR spatial signaling.
- Enhancing GPCR Research Outreach | Dr GPCR University early-bird registration ends soon!
Logo Contest : Let your creativity shine by submitting your design for the Logo Contest before August
- 📰 GPCR Weekly News, July 3 to 9, 2023
We're here to share the latest GPCR news with you. Congratulations to Dr.
- A robust and Efficient FRET-Based Assay for Cannabinoid Receptor Ligands Discovery.
The most used probe right now is the radioactive CP-55940, [3H-CP-55940].[11] Figure 1.
- Navigating the Signaling Network: RTK and GPCR Crosstalk Uncovered
Growth factor-dependent phosphorylation of Gαi shapes canonical signaling by G protein-coupled receptors
- 📰 GPCR Weekly News, August 7 to 13, 2023
Want to share your project in a casual way? Submit a 1-minute abstract video using this form!
- 📰 GPCR Weekly News, October 23 to 29, 2023
Illuminating the druggable genome: Pathways to progress Industry News Anatole Klepatsky, Orion's COO, Shared
- How a Failed Med School Dream Sparked a GPCR Biotech Revolution
In this episode, he shares his career story — one that begins with a failed goal, but ends up reshaping
- What's Going On with GPCRs?! Find Out in This Week's Update! ⦿ Nov 4 - 10, 2024
We can’t wait to share it with you!
- Structural landscape of the Chemokine Receptor system
adopting a hook-like conformation, whereas the chemokine antagonist ([5P7]CCL5) folds into a helical shape These receptors share a glutamine residue at the "toggle switch" position 6.48 and the disruption of
- 📰 GPCR Weekly News, January 23 to 29, 2023
Hello Readers👋, We're excited to share our weekly newsletter with you.
- Decoding Schild Analysis: The Pharmacologist’s Lens on Competitive Antagonism
When these same molecules act as antagonists, their curves shift not only in position but also in shape
- From Lab Logic to Leadership: How Scientific Thinking Holds Back Biotech Operations
And if your thinking is still shaped by academic norms, your startup will keep running like a lab, not
- 📰 GPCR Weekly News, May 1 to 7, 2023
We've got some GPCR updates to share with you. Take a look 👀!
- 📰 GPCR Weekly News, January 16 to 22, 2023
Hello Readers👋, We're excited to share our weekly newsletter with you.
- 📰 GPCR Weekly News - January 9 to 15, 2023
Hello Readers👋, We're excited to share our weekly newsletter with you.
- Artificial intelligence – faster, smarter, cheaper GPCR drug discovery
While they share similarities, there are notable differences in respect to neural network architecture The sharing and collaboration of data across academia, industry, and regulatory bodies will likely increase
- 📰 GPCR Weekly News, October 16 to 22, 2023
injury via Hedgehog-independent CREB signaling Ciliary localization of a light-activated neuronal GPCR shapes
- Orthosteric vs. Allosteric Interactions: The Silent Decider of Safety and Success
In drug discovery, orthosteric vs. allosteric isn’t just a mechanistic detail; it’s a decision that shapes
- Why Opposing Processes Matter for Your Next GPCR Drug
Some can make a mediocre drug shine.
- 📰 GPCR Buzz: August 5-11, 2024 | Top Highlights from DrGPCR University!
Logo Contest : Let your creativity shine!











