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- 📰 GPCR Weekly News, December 11 to 17, 2023
This week's highlights: Kudos to our partner, GPCR Therapeutics, for partnering with Bridge Biotherapeutics meta-dynamics/FMO3 approach Industry News GPCR Therapeutics Announces Out-Licensing Agreement with Bridge Biotherapeutics in Idiopathic Pulmonary Fibrosis Former execs from Pfizer obesity drug program have
- Twist Bioscience Launches Revelar Biotherapeutics to Develop and Commercialize Novel COVID-19...
November 2021 Twist Bioscience Launches Revelar Biotherapeutics to Develop and Commercialize Novel COVID offering of high-quality synthetic DNA using its silicon platform, today announced it has launched Revelar Biotherapeutics
- Trevena Receives up to $40M in OLINVYK ex-US Royalty-Based Financing from R-Bridge Healthcare ...
April 2022 Trevena Receives up to $40M in OLINVYK ex-US Royalty-Based Financing from R-Bridge Healthcare disorders, today announced that the Company entered into a royalty-based financing with an affiliate of R-Bridge Healthcare Fund (the R-Bridge Financing)."
- Ben Clements on Rescuing Opioids with GPCR Modulators
.” – Ben Clements By combining chronic pain models with receptor-level pharmacology, Ben is bridging With collaborations across medicinal chemistry and neuropathic pain research, Ben is bridging molecule
- A Note from Yamina: Building the Next Chapter of Dr. GPCR
These resources continue to bring the latest in GPCR science and industry updates to thousands across GPCR Foundry — our R&D and biotech hub designed to bridge GPCR science with execution. The Dr. GPCR Foundry: Science Meets Execution The Foundry is where we bring together biotech innovators, Venture Consulting Corner — a place for teams to get tailored scientific and strategic guidance that helps bridge They go beyond sponsorship to bring tools and technologies directly to the researchers who use them ,
- Is Your Agonist Really “Working”—Or Are You Just Seeing What Your System Allows?
If you're an emerging drug hunter, this lesson is your bridge from data confusion to predictive clarity
- Trevena Announces Receipt of First $15 million Tranche in Connection with its $40 million ...
of First $15 million Tranche in Connection with its $40 million ex-US Royalty-Based Financing with R-Bridge of the first $15 million tranche from its royalty-based financing agreement with an affiliate of R-Bridge Healthcare Fund (the R-Bridge Financing)."
- How a Failed Med School Dream Sparked a GPCR Biotech Revolution
his understanding of neurobiology and translational research models, further refining his interest in bridging The goal of Blue wasn’t just to publish or patent; it was to bring a novel, safer class of pain therapeutics in scientific rigor while embracing the tools of business and technology, he’s built a career that bridges
- Structural landscape of the Chemokine Receptor system
reveal common structural features, such as the presence of seven transmembrane domains (TMs 1-7), a bridge subfamily-defining CC/CXC/CX3C/XC motif is located in the N-loop and forms two conserved disulfide bridges When comparing the CKRs structures complexes, the disulfide bridges formed between the N-loop and the β3-strand align well, although the position of the disulfide bridges between the N-loop and the 30s-loop Two conserved disulfide bridges are found in chemokine receptors - one connects the N-terminus to the
- Dr. GPCR University registration is now open! Secure your spot now!
Senior Scientist, Cryo-Electron Microscopy Postdoctoral Research Associate Senior Scientist - Discovery Biotherapeutics
- 📰 GPCR Weekly News, October 16 to 22, 2023
at the Citeline Pharma Intelligence Awards Japan 2023 BioMap and Sanofi to co-develop AI modules for biotherapeutic
- Exploring the Breakthroughs in GPCR Research
Clinical Pharmacology 2026 GPCR Jobs NEW Postdoctoral Research Associate Senior Scientist - Discovery Biotherapeutics
- Trevena Announce Submission of New Drug Application in China for OLINVYK® by its Partner Jiangsu ...
for OLINVYK® by its Partner Jiangsu Nhwa Pharmaceutical "Submission supported by data from a Phase 3 bridging submitted by Trevena’s partner, Jiangsu Nhwa Pharmaceutical, and follows completion by Nhwa of a Phase 3 bridging
- Unlocking the Future of Medicine: Advancements in GPCR Research
Senior Scientist, Cryo-Electron Microscopy Postdoctoral Research Associate Senior Scientist - Discovery Biotherapeutics
- GPCR Happy Hour – Boston, Sept 2025
Our mission is simple: bridge science and industry by connecting researchers, biotech, CROs, and pharma Register Now 👉 Bring a colleague you trust . 👉 Don’t miss the chance to be part of the conversations
- Predicting GPCR Function: Inside the Carlsson Lab’s Modeling Toolbox
That medicinal chemistry capacity is unusual for a modeling lab and provides a critical bridge between By focusing on translationally relevant predictions , the lab helps bridge the gap between computation
- Novel interaction between neurotrophic factor-α1/carboxypeptidase E and serotonin receptor, 5-HTR1E,
Molecular dynamics studies revealed that NF-α1/CPE interacts with 5-HTR1E via 3 salt bridges, stabilized intracellular loop 3 (ICL3) of NF-α1/CPE-5-HTR1E, it recruited β-arrestin1 by forming numerous salt bridges
- Irreversible Drugs, Real Control: Design for Durable Target Engagement
Kenakin live and bring the questions that keep you thinking. Bridge the aisle —modelers × experimentalists for faster iteration. Listen to the episode ➤ Why Dr. Access this week’s full Premium Edition here ➤ What our members say "Thank you for bringing this course
- Signals in Motion: Pain, Metabolism & Terry’s Corner
It will bridge foundational receptor theory with today’s most pressing pharmacological questions, from
- 📰 GPCR Weekly News, July 1 to 7, 2024
2026 GPCR Jobs HIGHLIGHT Principal Scientist, In vitro pharmacology NEW Senior Scientist - Discovery Biotherapeutics
- Jan Steyaert Named 2022 Jacob and Louise Gabbay Award Winner
Steyaert bridged fundamental high-impact research in biomedical sciences with the mechanistic understanding
- How Understanding Intracellular Drug Access Can Transform Your GPCR Drug Discovery Program
Exploring Intracellular Targets: Bridging the Gap Between In Vitro and In Vivo GPCR Research - August Bridge the gap between disciplines: Get practical advice from a computational expert on how wet-lab
- Accelerating GPCR Drug Discovery: What 40 Years of Pharmacology Reveal
That’s exactly what Terry’s Corner was built to do: bring four decades of frontline discovery insight You must bridge that gap,” Kenakin notes. “In industry, scientists bring targets forward. There’s no central committee handing down orders.
- How to Use Statistical Methods to Strengthen Every GPCR Drug Discovery Decision
Bring the curve you’re debating. Ask. Challenge. Get an answer you can defend. Ajay Yekkirala shares the journey from academic pharmacologist to biotech entrepreneur—bridging curiosity
- Discovery of 3(2-aminoethyl)-thiazolidine-2,4-diones as a novel chemotype of sigma-1 receptor ligand
In addition, molecular docking predicted that all the compounds showed the critical salt bridge with
- From Failed Experiments to Predictive GPCR Models
Bridging Computation and Collaboration While Carlsson began his scientific career with a deep skepticism Many of his former students now work in industry, where their ability to bridge the computational-experimental
- AlphaFold’s Breakthrough in GPCR Research: Revolutionizing Discovery, Yet Awaiting Experimental Proof
computational techniques, could help overcome these limitations, leading to more comprehensive models that bridge
- Mechanism vs. Assumption: A Model-First Path to Getting GPCR MoA Right
Bring the curve you’re debating. Ask. Challenge. Get an answer you can defend. Target 2025 – GPCR Speaker Spotlight DOT 2025 (Sept 22–25, Boston) is set to be a high-signal GPCR forum—bridging
- Isoforms of GPR35 have distinct extracellular N-termini that allosterically modify...
We found that a proposed disulfide bridge between the N-terminus and extracellular loop 3, present in
- Fentanyl and Xylazine: Why Breathing Fails in Overdose
When I combined the two drugs, there was a potentiation of fentanyl’s effect on tidal volume—mice were bringing Why This Research Matters Beyond the Lab Catherine’s findings bridge the gap between basic receptor biology



















