Search Results

Professor Deane joins Exscientia’s technology leadership team, reporting to Chief Technology Officer, Garry Pairaudeau.

GPCR-targeting antibodies GPCR Inhibition With ICB May Be Needed to Reactivate Antitumor Immune Response Garry Pairaudeau, CTO of Exscientia discuss transforming drug discovery using their AI-driven platform Salipro

And that’s exactly what carries strong discovery programs into 2026. GPCR Year in Review: Carrying Better Experiments Into 2026 As 2025 closes, the Dr.

, Head of Research, Peter McNamara, PhD, to Chief Scientific Officer as well as the appointments of Barry

The purpose of the STSM is to carry out a collaborative research project on topics relevant to the network

We also take into account the detrimental effect of mutations carried by distinct signalling proteins

Western blot and RT–qPCR assays were carried out to measure the downstream factors of the interaction

We have cloned and characterized SK and SKR genes in the D. armandi and carried out bioinformatics predictions

Schjoldager KT et al. 2020), and usually capped by a single sialic acid, although, in rare cases glycans can carry The atypical chemokine receptor 2 (ACKR2), US28 and sphingosine-1-phosphate receptor 1 (S1PR1) also carry may also contribute to the observed phenotype since many glycosyltransferases and the two TPSTs also carry

Temperature optimization studies were carried out using HEK293H cells transiently transfected with the

We have carried out MARTINI coarse-grained molecular dynamics simulations of SMO in POPC and in ciliary

This emotional spark carried the team through the next steps — validation, iteration, and expanding the

Every GPCR assay that makes it to market carries years of failures, late-night ideas, risky bets, and

Drugs carry dual mechanisms. At equilibrium, these effects cancel. But kinetics unmasks them.

Let’s unpack the three core “rules” most scientific founders unconsciously carry into their companies

One carries broad off-target risk; the other behaves more like a high-affinity ligand with slow dissociation

treat cancer and inflammation AVROBIO and Tectonic Therapeutic Announce Merger Trevena Inc Elevates Barry

Chemistry, and Physiology or Medicine, the most recognizable awards for the impact of scientific work carried Richard Axel and Linda Brown Buck for their work on Class-A olfactory receptors.[57–61] The two jointly carried on GPCR function.[62–66] Lefkowitz was able to isolate β-adrenergic receptors from tissue samples to carry

assay is suitable for measuring the K i of different ligands, competition binding measurements were carried Also, competition experiments were carried out to demonstrate the versatility of this system (Figure

characteristic provides a major advantage in drug discovery: massive parallel library-based screening can be carried