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  (5) Meldal, M.; Tornøe, C. W. Cu-Catalyzed Azide−Alkyne Cycloaddition. Chem.

Soave M, Briddon SJ, Hill SJ, Stoddart LA.

Miranda-Pastoriza D, Bernárdez R, Azuaje J, Prieto-Díaz R, Majellaro M, Tamhankar AV, Koenekoop L, González

Bouvier, M., Oligomerization of G-protein-coupled transmitter receptors.  

SMOOTHENED-PKA signaling in the Hedgehog cascade Elita Yuliantie , Arthur Christopoulos , Patrick M.

M., & Lefkowitz, R. J. (2003).

Burger , Arthur Christopoulos , David M.

This week's highlight includes congrats to: Makaía M Papasergi-Scott, Peter Gmeiner, Brian K Kobilka,

Anson, M., et al., Incidence of new onset type 2 diabetes in adults living with obesity treated with

Continuing Study Addex Therapeutics in the 23rd BioEquity Europe Conference Simon Bekker-Jensen and Mette M

Devki D Sukhtankar and Pina M Cardarelli's research: Burixafor Hydrobromide (GPC-100) effects on hematopoietic

Magdalena M Scharf, Antonella Di Pizio, Ines Liebscher, Hannes Schihada, and Gunnar Schulte et al. on

K ´ onigstorfer, M. Mozhayeva, Y. Sara, T.C. Südhof, and ¨ E.T. Kavalali. 2001.

Nayara Braga Emidio, Ross Cheloha, Laura M Wingler, et al. for their work on Nanobody-Mediated Dualsteric

Maziarz, M., et al., Revealing the Activity of Trimeric G-proteins in Live Cells with a Versatile Biosensor

a GPCR Paper with his team: Targeted Drug Design through GPCR Mutagenesis: Insights from β2AR China M

insights into G protein coupling specificity at a class A GPCR Jianjun Cao, Arthur Christopoulos, Patrick M.

genito-urinary system, the activation of ORs was shown to influence the motility of spermatozoa (Spehr M.

GPCRs, Ion Channels, and Transport Proteins (March 24 - 29, 2024) GPCR Jobs NEW Postdoctoral Fellow, Caron

More specifically, this review covers assays to monitor the canonical G protein signaling pathway (e.g recruitment/activation, inositol phosphate accumulation, or Ca2+ mobilization), assays to monitor non-canonical

Check out our new on-demand course on non-canonical GPCR behaviors and a podcast episode tracing 30 years

Senior Scientist- Membrane Technologies NEW Computational Protein Design (GPCR) Postdoctoral Fellow, Caron

highlighted a new hydrophobic conserved motif composed of phenylalanine (F)/leucine (L) and methionine (M)

December 2021 "Dame Carol Robinson DBE, FRS, FRSC, FMedSci, Oxford University’s first female Professor

October 2022 "G protein-coupled receptors (GPCRs) are important drug targets characterized by a canonical

Surgery Senior Scientist- Membrane Technologies Computational Protein Design (GPCR) Postdoctoral Fellow, Caron

Aaron McGrath from Takeda. He joins Dr. pockets and druggability 🔹 The role of cryo-EM in capturing fully activated GPCR complexes 📅 Catch Aaron

October 2022 "The canonical model for G protein-coupled receptors (GPCRs) activation assumes that stimulation

Here, we determine that GRKs phosphorylate a non-canonical substrate, anterior pharynx-defective 1A (

various cellular processes such as cell proliferation, migration, apoptosis, and transcription via canonical