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Aspergillus ochraceus quorum sensing through the GprC-AcyA pathway Deciphering the genetic landscape of lumpy $4.6 Million in Milestone Payments from Centessa Pharmaceuticals CB1 receptor inverse agonist improves lung

Don’t be surprised if you find yourself singing Daddy Yankee’s “Gasolina” from the top of your lungs while executing your best perreo or Luis Enrique’s “Yo no sé mañana” while a stranger takes you floating

FRET and BRET sensors operate on the principle of energy transfer between a fluorescent or luminescent Luttrell, and M.H. Lee, Probing Arrestin Function Using Intramolecular FlAsH-BRET Biosensors. 

This week's highlight includes congrats to: Luca Franchini and Cesare Orlandi for their research on Deorphanization

Chemically Diverse "Superscaffold" Library Enables Ligand Discovery for a Key GPCR Target Gunnar Schulte, Lukas

C., Lundin, L. G., & Schiöth, H. B. (2003).

al. for their research on Time-resolved cryo-EM of G-protein activation by a GPCR Remi Janicot, Alex Luebbers

prefrontal cortex cells and circuits GPCRs in Oncology and Immunology RGS20 promotes non-small cell lung

S., Hunyady, L., Luttrell, L. M., & Lefkowitz, R. J. (2003).

elegan Species-Specific Duplicated FMRFaR-like Gene A62 Regulates Spontaneous Locomotion in Apolygus lucorum A Perspective on Class C GPCR Based Genetically Encoded Biosensors Emergence of lumpy skin disease virus

for FY2023 Financial Results Novartis Automates New Radioligand Therapy Production Plant Novartis’ Lutathera

nascent GPCRs in the ER-to-Golgi transport by CCHCR1 via direct interaction Industry News Novartis Lutathera

disorder GPCRs in Oncology and Immunology Regulator of G protein signaling protein 6 alleviates acute lung

neurosteroid concept to metabolomics: New insights into pregnenolone function Molecular characterization of lumpy

for the Treatment of Insomnia OMass Therapeutics Releases First Protein Structures in PDB, Advances Lupus

human islets AT2 receptor agonist LP2 restores respiratory function in a rat model of bleomycin-induced lung G protein-coupled receptor 37 promotes resistance to cisplatin-induced apoptosis in non-small cell lung

Transforming Growth Factor β-Mediated Antifibrotic G Protein-Coupled Receptor Landscape Tampering in Lung

Lukas Grätz, David Gloriam, and Gunnar Schulte’s research on Unveiling pathway selectivity in Frizzleds

Immunology Minireview: functional roles of tissue kallikrein, kinins, and kallikrein-related peptidases in lung

GPCRs in Oncology and Immunology A2aR on lung adenocarcinoma cells: A novel target for cancer therapy

patients with WHIM syndrome Bristol Myers Squibb’s Investigational LPA1 Antagonist Reduces the Rate of Lung

Hay, Lukas Grätz, and more. Check out some of the latest GPCR discoveries below!

DRD1 is exempt from TGFβ-mediated antifibrotic GPCR landscape tampering in lung fibroblasts. βHB inhibits

First complete genome sequence of lumpy skin disease virus directly from a clinical sample in South India

interactions between the negative sulfate groups in the N-terminus and the positively charged chemokines (Ludeman

and Target Engagement Novo Nordisk's GLP-1 for Type II diabetes approved for first-line treatment The Lundbeck

analyses, have indicated that OR genes are also expressed in non-olfactory tissues including the testis, lung In non-small-cell lung cancer OR2J3 activation induced apoptosis and inhibited cell proliferation and

Transcriptome profiling of male and female Ascaris lumbricoides reproductive tissues.

Knockdown of GPR125 as well as that of Dlg1 results in formation of aberrant cysts with multiple lumens

In a LPS-induced lung inflammation model in mice, ACT-660602 led to significantly reduced recruitment