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The chemistry originated from Parker’s lab.

This fundamental disconnect between the lab and the boardroom  is precisely where programs get stuck—not

Podcast: When GPCR Tools Scale Even the most elegant tools only matter when they scale beyond a single lab

Ion Channels, and Transport Proteins (March 24 - 29, 2024) GPCR Jobs NEW Postdoctoral Fellow, Caron Lab

Most labs default to “n=3” or “n=6.”

Scientist- Membrane Technologies NEW Computational Protein Design (GPCR) Postdoctoral Fellow, Caron Lab

and Signaling Monitoring the Reversibility of GPCR Signaling by Combining Photochromic Ligands with Label-free Annual Meeting IRN I-GPCRNet (October 25 - 27, 2023) GPCR Jobs NEW Postdoctoral Research Associate NEW Lab

noise or delays: Industry insights:  Structure-Based Drug Design Summit; AI-Powered GPCR Research; Lab-in-the-Loop

2023) GPCR Jobs NEW Associate Director / Director, Clinical Operations Postdoctoral Research Associate Lab

Bridge the gap between disciplines:  Get practical advice from a computational expert on how wet-lab

However, DL algorithms typically require large amounts of labelled training data comprising millions understanding of GPCRs, ligands, diseases, and their associations: open-access databases from experimental labs tools for researchers: AI solutions which bring together theoretical, computational, and experimental labs

Early images showed clean, bright labeling across whole pancreatic islets. accelerated discovery and reduced noise, helping them understand how each design change influenced labeling It also gave them confidence in how the probes would perform once shipped to external labs. These optimizations enabled dual-color labeling strategies, surface-selective imaging, and ultimately

of Glioblastoma Associate Director / Director, Clinical Operations Postdoctoral Research Associate Lab

Sudarshan Rajagopal and their lab team study on 'Location bias: A "Hidden Variable" in GPCR pharmacology Structural Biology NEW Research Specialist NEW Science Research Writer Postdoctoral Fellow Research Laboratory

K., Gellman, S. H., Pautsch, A., Steyaert, J., Weis, W. I., & Kobilka, B. K. (2011).

Jobs NEW Senior Researcher in Structural Biology NEW Post-Doctoral Fellow Postdoctoral Fellow Research Laboratory Scientist Principal Investigator, In Vitro Biology Associate Scientist Postdoctoral Scholar - O’Neill Lab

Gilman, A.G., G proteins: transducers of receptor-generated signals. 

biophysical fragment screening using polymer-encapsulated nanodiscs Google DeepMind And Isomorphic Labs

In every lab, candidates fail not because they lack potency at a receptor, but because they stumble at

AI-Driven Approach to Modern Drug Discovery Arcoscreen will present in the start-up village at Future Labs

NEW Principal Investigator, In Vitro Biology NEW Associate Scientist Postdoctoral Scholar - O’Neill Lab

World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Postdoctoral Scholar - O’Neill Lab

(A) After experimental design, wet lab work is performed to acquire high-content cell images, which then CB 2 -expressing HEK cell lines are labeled with CELT-331 at 80 nM (right), while competition with the

Hannes Schihada and his lab team developed fluorescent analogues for real-time binding studies of orphan

of Glioblastoma Associate Director / Director, Clinical Operations Postdoctoral Research Associate Lab

Here’s how that mindset plays out in practice: You align trial endpoints with future label claims , not

Avoid misleading mechanistic labels  → NAMs, PAMs, and biased agonists behave in system-dependent ways

NAMs, PAMs, and Subtle Mechanistic Traps Modulators are frequently labeled correctly but characterized

By using two labeled ligands the transference of energy event will only happen when the adequate distance are bound to is promiscuous, it will not compromise assay integrity the same way it would in single-label

A new contributor article from our friends at Celtrays Research outlines how dual-labeled fluorescent Dual-label specificity blocks promiscuous ligand confusion Lanthanide donors + d2 acceptors = high SNR