Search Results

different modes of action of Adhesion GPCRs and found that they do not only mediate classical G protein signals Today, she and her team are working on the questions of how Adhesion GPCRs integrate the different signals

Stay at the Forefront of GPCR Drug Discovery Gain insider methods from the pioneers shaping biased signaling Sam Hoare Pharmechanics GPCR signaling & biased agonism expert regularly consulted by top pharma companies A deep-dive training session led by top GPCR scientists, covering pharmacology, signaling, assays, and

communication, she is poised to make valuable contributions to the field and expand our understanding of GPCR signaling computational methods like molecular dynamics simulations and free energy landscape analysis to understand the signaling molecular pharmacology, his research focuses on elucidating the molecular basis of membrane protein signalling

Research interests: Signaling mechanisms involving GPCRs and heterotrimeric G proteins" Dr.

Much of his work is based on GPCR signaling in the context to cardiovascular diseases.

structural biologist interested in the molecular mechanisms controlling how class C GPCRs transmit signals

Mikel Garcia-Marcos which investigates GPCR and G protein signaling" Remi Janicot on the web Boston University pharmacology, and structural biology to study how different types of ligands modulate angiotensin receptor signaling

A large component of his work is centered around dysregulated signaling in cancer and the development

technologies to solve broad questions in pharmacology, with a specific focus on G-protein coupled receptor signaling

In this episode, Silvio discusses G protein signaling in the context of cancer, immunotherapies, and

He is exploiting the emerging information on dysregulated signaling circuitries and individual genomic

Health and Disease, Metabolism, Nervous System, Proteomics and Transcriptomics, Receptor Structure, Signaling of thermogenic fat Vasiliki Karagiannakou GAIN Domain Dynamics And Its Relevance For Adhesion GPCR Signaling However, the physiological relevance of flap flexibility on receptor activation and signaling remains We are investigating the relevance of GAIN domain dynamics for aGPCR signaling in Drosophila melanogaster Lphn3/Adgrl3) undergo physiologically relevant alternative splicing, which determined heterotrimeric signaling

focused on developing new pharmacological tools via chemistry and protein engineering to interrogate GPCR signaling

To further define the role of atypical p38 signaling responses we are studying how atypical p38 controls

findings identify nanoscale GPCR spatial organization as an integral element of their activity and signaling

Metabolic GPCRs Meet Inoviem Team GPCR ECI Transatlantic 2022 Editorial: GPCR and G Protein-Mediated Signalling

Hanyaloglu's lab at ICL + Dr Perrais' lab at IINS) focused on understanding the interplay between GPCR signalling

underlined Indicate abstract category on top left corner (up to 2 categories max) Abstract categories Signaling

Drug Design and Pharmacology in Copenhagen, he worked on novel analytical methods to identify human signaling

the 1994 Nobel Prize in Physiology or Medicine for their discovery of G-proteins and their role in signal

communication, she is poised to make valuable contributions to the field and expand our understanding of GPCR signaling

He has been also studying what aspects of GPCR signaling are regulated in a sex-selective manner and

Graham studied Biochemistry at the University of Birmingham before completing a Ph.D. in yeast pheromone signaling

approaches (synthesis, modeling, pharmacology) to study G protein-coupled receptors (GPCRs) and purinergic signaling

GPCR Podcast ➚ Articles from the Ecosystem ➚ First AMA of 2026: GPCR Pharmacology, Biased Signaling &

Wellcome Trust Senior Research Fellowships Andrew established a reputation in the field of receptor signaling

He has been also studying what aspects of GPCR signaling are regulated in a sex-selective manner and

Jawaharlal Nehru University in India and it was during a biochemistry class where he learned about cell signaling

Würzburg, where I later became Heisenberg Professor for 'Physiology and pathophysiology of mechanoceptive signalling

Solutions Determine rank-order hits, evaluate ligand bias or allostery, study multiple targets and signaling Access Product Solutions and Key Resources GPCR Functional Cell-Based Assays - Assessing Biased Signaling