Search Results
Results found for "Tao Che"
- GPCR kinase phosphorylation of distal C-tail sites specifies βarrestin1-mediated signaling by...
provide evidence that distal carboxyl-terminal tail (C-tail), but not proximal, phosphorylation of the chemokine We demonstrate by pharmacologic inhibition of GRK2/3-mediated phosphorylation of the chemokine receptor
- CCL25/CCR9 interaction promotes the malignant behavior of salivary adenoid cystic carcinoma via...
malignant behavior of salivary adenoid cystic carcinoma via the PI3K/AKT signaling pathway "Background CC chemokine receptor 9 (CCR9), an organ-specific chemokine receptor, interacts with its exclusive ligand CCL25 to
- GRK3 is a poor prognosticator and serves as a therapeutic target in advanced gastric adenocarcinoma
We identified a novel GRK3 inhibitor, LD2, through a chemical-library screen.
- Platelets in the NETworks interweaving inflammation and thrombosis
Platelet α-granules contain microbicidal proteins, chemokines and growth factors, which upon release
- Learn about Dr. GPCR Ecosystem!
Come check out the brand new Dr. GPCR Ecosystem and explore its benefits!
- Trevena Announces Advancement of TRV045 Into Clinical Development for Diabetic Neuropathic Pain
TRV045 safety, tolerability, and PK in healthy volunteers Enrollment expected to start in early Q1 2022 CHESTERBROOK
- Professor Charlotte Deane Joins Exscientia as Chief Scientist of Biologics AI
Professor Deane holds a B.A. in Chemistry from the University of Oxford and a Ph.D. in Biochemistry from
- Targeted Therapies to Reduce Side Effects in Modern Drug Development
For example, chemotherapy, a powerful standard approach to kill fast-growing cancer cells, has the drawback
- Trevena Reports Second Quarter 2022 Results and Provides Business Update
August 2022 "CHESTERBROOK, Pa., Aug. 11, 2022 (GLOBE NEWSWIRE) -- Trevena, Inc.
- Effects of Small Molecule Ligands on ACKR3 Receptors
August 2022 "Abstract Chemokines such as stromal derived factor 1 and their G protein coupled receptors C-X-C motif chemokine ligand 12 (CXCL12) has two receptors: C-X-C chemokine motif receptor 4 (CXCR4) and atypical chemokine receptor 3 (ACKR3). SIGNIFICANCE STATEMENT: We are interested in the signaling produced by the G protein coupled receptor atypical chemokine
- John Streicher talks about his work on terpenes found in cannabis as these may be a novel way to ...
people are familiar with cannabis, but John Streicher, PhD, takes a closer look at the plant’s aromatic chemical
- Trevena Receives up to $40M in OLINVYK ex-US Royalty-Based Financing from R-Bridge Healthcare ...
in OLINVYK ex-US Royalty-Based Financing from R-Bridge Healthcare Fund, an affiliate of CBC Group "CHESTERBROOK
- Trevena Announces Receipt of First $15 million Tranche in Connection with its $40 million ...
Tranche in Connection with its $40 million ex-US Royalty-Based Financing with R-Bridge Healthcare Fund "CHESTERBROOK
- Trevena Announce Submission of New Drug Application in China for OLINVYK® by its Partner Jiangsu ...
payments upon approval and commercialization milestones, as well as a 10% royalty on net sales in China CHESTERBROOK
- Self-docking and cross-docking simulations of G protein-coupled receptor-ligand complexes
Ligand discovery aimed at identification of chemical tools and drug leads is aided by molecular docking
- G-protein-coupled receptors as therapeutic targets for glioblastoma
Treatments include surgical resection, radiotherapy, and chemotherapy. To date, the most promising targets are the chemokine, cannabinoid, and dopamine receptors, but future
- GPCRS: AN ODYSSEY FROM STRUCTURE, SIGNALING AND REGULATION TO THERAPEUTICS
Coupled with their ability to respond to a highly diverse range of chemical stimuli, they represent the
- TeachOpenCADD - A teaching platform for computer-aided drug design
Open source programming packages for cheminformatics and structural bioinformatics are powerful tools practical aspect of these topics, the platform addresses students and researchers with a biological/chemical
- OMass Therapeutics's founder, Carol Robinson, has been awarded the prestigious Louis-Jeantet ...
Louis-Jeantet Prize for Medicine 2022 by the Louis-Jeantet Foundation and the 2022 Benjamin Franklin Medal in Chemistry Louis-Jeantet Prize for Medicine 2022 by the Louis-Jeantet Foundation and the 2022 Benjamin Franklin Medal in Chemistry
- Genome-wide identification of 216 G protein-coupled receptor (GPCR) genes from the marine water ...
orthological relationship of amine, neuropeptide, and opsin receptor repertoire, while purinergic and chemokine
- Trevena Adds Seasoned Biopharma Commercial Executive to Senior Leadership Team
November 2021 "November 11, 2021 7:00am EST Patricia Drake appointed new Chief Commercial Officer CHESTERBROOK

