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- How Schild Analysis Protects Your Conclusions in GPCR Research
integrated view of publications, events, insights, and opportunities designed to support your career, your lab
- Innovative Data-Driven Solutions: The pHSense Revolution
The chemistry originated from Parker’s lab.
- Is Your GPCR Drug Discovery Program Built for Breakthroughs or Breakdowns?
This fundamental disconnect between the lab and the boardroom is precisely where programs get stuck—not
- 📰 GPCR Weekly News, July 3 to 9, 2023
Ion Channels, and Transport Proteins (March 24 - 29, 2024) GPCR Jobs NEW Postdoctoral Fellow, Caron Lab
- 📰 GPCR Weekly News, July 10 to 16, 2023
Scientist- Membrane Technologies NEW Computational Protein Design (GPCR) Postdoctoral Fellow, Caron Lab
- Curve Shifts Don’t Lie, But Your Eyes Might
Most labs default to “n=3” or “n=6.”
- 📰 GPCR Weekly News, May 15 to 21, 2023
and Signaling Monitoring the Reversibility of GPCR Signaling by Combining Photochromic Ligands with Label-free Annual Meeting IRN I-GPCRNet (October 25 - 27, 2023) GPCR Jobs NEW Postdoctoral Research Associate NEW Lab
- Why Kinetics Matter More Than Kd in GPCR Drug Discovery
noise or delays: Industry insights: Structure-Based Drug Design Summit; AI-Powered GPCR Research; Lab-in-the-Loop
- 📰 GPCR Weekly News, May 22 to 28, 2023
2023) GPCR Jobs NEW Associate Director / Director, Clinical Operations Postdoctoral Research Associate Lab
- Artificial intelligence – faster, smarter, cheaper GPCR drug discovery
However, DL algorithms typically require large amounts of labelled training data comprising millions understanding of GPCRs, ligands, diseases, and their associations: open-access databases from experimental labs tools for researchers: AI solutions which bring together theoretical, computational, and experimental labs
- How Understanding Intracellular Drug Access Can Transform Your GPCR Drug Discovery Program
Bridge the gap between disciplines: Get practical advice from a computational expert on how wet-lab
- How Collaboration Sparked a GPCR Imaging Breakthrough in Chemical Biology
Early images showed clean, bright labeling across whole pancreatic islets. accelerated discovery and reduced noise, helping them understand how each design change influenced labeling It also gave them confidence in how the probes would perform once shipped to external labs. These optimizations enabled dual-color labeling strategies, surface-selective imaging, and ultimately
- 📰 GPCR Weekly News, June 5 to 11, 2023
of Glioblastoma Associate Director / Director, Clinical Operations Postdoctoral Research Associate Lab
- 📰 GPCR Weekly News, August 21 to 27, 2023
Sudarshan Rajagopal and their lab team study on 'Location bias: A "Hidden Variable" in GPCR pharmacology Structural Biology NEW Research Specialist NEW Science Research Writer Postdoctoral Fellow Research Laboratory
- 📰 GPCR Weekly News, January 8 to 14, 2024
Jobs NEW Senior Researcher in Structural Biology NEW Post-Doctoral Fellow Postdoctoral Fellow Research Laboratory Scientist Principal Investigator, In Vitro Biology Associate Scientist Postdoctoral Scholar - O’Neill Lab
- 📢 Early Bird Registration Ends Tomorrow! | Sep 16 - 22, 2024
biophysical fragment screening using polymer-encapsulated nanodiscs Google DeepMind And Isomorphic Labs
- Enzyme Inhibition Pharmacology: The Hidden Gatekeepers of GPCR Drug Discovery
In every lab, candidates fail not because they lack potency at a receptor, but because they stumble at
- GASP1 enhances malignant phenotypes of breast cancer cells and decreases their response to...
IGF1, in turn, stimulated GASP1 expression by activating the PI3K/AKT pathway, forming a vicious cycle propelling
- 📰 GPCR Weekly News, February 27 to March 5, 2023
AI-Driven Approach to Modern Drug Discovery Arcoscreen will present in the start-up village at Future Labs
- 📰 GPCR Weekly News, February 26 to March 3, 2024
Franziska Heydenreich, Sudarshan Rajagopal, Graham Ladds, Cesare Orlandi, Simone Prömel and Michel Bouvier pharmacology Research Fellow Postdoctoral Fellow – Molecular Pharmacology of Feeding Behavior Director of Laboratory
- 📰 GPCR Weekly News, December 18 to 31, 2023
NEW Principal Investigator, In Vitro Biology NEW Associate Scientist Postdoctoral Scholar - O’Neill Lab
- 📰 GPCR Weekly News, December 11 to 17, 2023
World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Postdoctoral Scholar - O’Neill Lab
- High-Content Screening for GPCR Programs: Overcoming Assay Limitations with Fluorescent Ligands
(A) After experimental design, wet lab work is performed to acquire high-content cell images, which then CB 2 -expressing HEK cell lines are labeled with CELT-331 at 80 nM (right), while competition with the
- 📰 GPCR Weekly News, October 30 to November 4, 2023
Hannes Schihada and his lab team developed fluorescent analogues for real-time binding studies of orphan
- 📰 GPCR Weekly News, May 29 to June 4, 2023
of Glioblastoma Associate Director / Director, Clinical Operations Postdoctoral Research Associate Lab
- 📰 GPCR Weekly News, April 22 to 28, 2024
This week's highlight includes congrats to: André Nguyen Dietzsch, Simone Prömel, et al. for their work
- Illuminating GPCR Research: FRET and BRET-Based Sensors Shed Light on Cellular Signaling
As technology continues to advance, leveraging RET-based sensors will undoubtedly continue to propel
- Unlock the Future of GPCR Science: Breakthroughs and Courses Await | Sep 2 - Sep 8, 2024
Weekly Highlights: Congrats to: Daniel Matúš , Simone Prömel , et al., for their work on The N terminus-only
- FDA Approval Is a Strategy Obstacle, Not a Paperwork Problem
Here’s how that mindset plays out in practice: You align trial endpoints with future label claims , not
- How System-Level GPCR Thinking Prevents Discovery Failures
Avoid misleading mechanistic labels → NAMs, PAMs, and biased agonists behave in system-dependent ways














