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Results found for "Lauren T May"
- Inversago Pharma appoints Glenn S. Vraniak as Chief Financial Officer
May 2022 "MONTREAL (CANADA) – May 17, 2022 – Inversago Pharma Inc.
- Cell-Type-Specific Effects of the Ovarian Cancer G-Protein Coupled Receptor (OGR1) on Inflammation..
We then demonstrate that sub-cellular localization and alternative signaling pathways may be responsible Our results suggest that strategies to selectively target OGR1 expression may represent a novel therapeutic
- PH-Binding Motif in PAR4 Oncogene: From Molecular Mechanism to Drug Design
We propose that Pc(4-4) may serve as a powerful drug not only toward PAR-expressing tumors but also for Pc(4-4) may become a promising candidate for future therapeutic cancer treatment."
- 📰 GPCR Weekly News, February 27 to March 5, 2023
(May 22 - 26, 2023) 2nd LEAPS Meets Life Sciences Conference. (May 14 - 19, 2023) 8th and final ERNEST Meeting in Crete. (May 3 - 7, 2023).
- 🤯Mind-blowing GPCR Scoops! Discover the Latest Breakthroughs! ⦿ Nov 18 - 24, 2024
April 24 - 27, 2025 | American Physiology Summit 2025 April 25 - 30, 2025 | AACR Annual Meeting 2025 May 12 - 15, 2025 | PEGS 2025 May 20 - 22, 2025 | SLAS Europe 2025 June 16 - 19, 2025 | BIO International
- 📰 GPCR Weekly News, March 13 to 19, 2023
(May 22 - 26, 2023) 2nd LEAPS Meets Life Sciences Conference. (May 14 - 19, 2023) 8th and final ERNEST Meeting in Crete. (May 3 - 7, 2023).
- Opioid Receptors and Protonation-Coupled Binding of Opioid Drugs
Pain may associate with inflamed tissue characterized by acidic pH. typically have a protonated amino group that contributes to receptor binding, and the functioning of GPCRs may
- AcroScreen co-founder Margaux Duchamp has been selected as a 30 under 30 Europe Forbes ranking 2022
May 2022 "We are thrilled to announce that our co-founder Margaux Duchamp has been selected as a 30 under
- ⛵Sailing the GPCR Seas: Your Weekly Research Voyage! ⦿ Nov 11 - 17, 2024
April 24 - 27, 2025 | American Physiology Summit 2025 April 25 - 30, 2025 | AACR Annual Meeting 2025 May 12 - 15, 2025 | PEGS 2025 May 20 - 22, 2025 | SLAS Europe 2025 June 16 - 19, 2025 | BIO International
- Integration and Spatial Organization of Signaling by G Protein-Coupled Receptor Homo- and ...
The recognition that GPCRs may physically interact with each other has led to the hypothesis that their distinct cell compartments along the plasma membrane where confined increases in second messengers may
- 📰 GPCR Weekly News, July 1 to 7, 2024
Specifically, the ideas discussed cover the complex pleiotropic behaviors of GPCRs and how these may schizophrenia Single nucleotide variations encoding missense mutations in G protein-coupled receptors may
- Dimerization of GPCRs: Novel insight into the role of FLNA and SSAs regulating SST2 and SST5...
receptors (SSTs) are class A GPCRs abundantly expressed in pituitary tumors where they represent the main Moreover, whether octreotide or pasireotide may play modulatory effects and whether FLNA may participate
- Exciting GPCR Events for Next Year! + GPCR Weekly Rocket Launch ⦿ Oct 28 - Nov 3, 2024
- 27, 2025 | American Physiology Summit 2025 NEW April 25 - 30, 2025 | AACR Annual Meeting 2025 NEW May 12 - 15, 2025 | PEGS 2025 NEW May 20 - 22, 2025 | SLAS Europe 2025 NEW June 16 - 19, 2025 | BIO International
- G protein-coupled receptor 21 in macrophages: An in vitro study
Studies of GPR21 knock-out mice indicated that GPR21 may be involved in promoting macrophage migration
- Trevena Announces Advancement of TRV045 Into Clinical Development for Diabetic Neuropathic Pain
Food and Drug Administration (FDA) that the study may proceed.
- Adenosine receptor signalling in Alzheimer's disease
Despite a better understanding of the disease, the current mainstay of treatment cannot modify pathogenesis provide insights into some novel strategies, including allosterism and the targeting of oligomers, which may
- Upregulation of Phospholipase C Gene Expression Due to Norepinephrine-Induced Hypertrophic Response
PLC activities self-regulate the expression of PLC isozymes with the suggestion that PLC activities may
- Activation of the human chemokine receptor CX3CR1 regulated by cholesterol
upon activation than previously solved class A GPCR-Gi complex structures is observed in CX3CR1, which may
- Community guidelines for GPCR ligand bias: IUPHAR review 32
Ligands eliciting biased signalling may constitute better drugs with higher efficacy and fewer adverse
- Adenosine receptor signalling in Alzheimer's disease
Despite a better understanding of the disease, the current mainstay of treatment cannot modify pathogenesis provide insights into some novel strategies, including allosterism and the targeting of oligomers, which may
- GPR110, a receptor for synaptamide, expressed in osteoclasts negatively regulates osteoclastogenesis
August 2022 "Bone remodeling is precisely regulated mainly by osteoblasts and osteoclasts. Considering that synaptamide is the endogenous metabolite of DHA, we hypothesized that DHA may inhibit
- 📰 GPCR Weekly News, January 30 to February 5, 2023
(May 22 - 26, 2023) 2nd LEAPS Meets Life Sciences Conference. (May 14 - 19, 2023) 8th and final ERNEST Meeting in Crete. (May 3 - 7, 2023).
- The complicated lives of GPCRs in cardiac fibroblasts
We discuss how such events may be distinct depending on where the GPCRs and their associated signaling
- 📰 GPCR Weekly News - January 9 to 15, 2023
(May 22 - 26, 2023) 2nd ERNEST Training School. (February 20 - March 3, 2023). GEM2023. (May 3-7, 2023). The Illuminating the Understudied Druggable Proteome Conference.
- Therapeutic validation of an orphan G protein-coupled receptor: The case of GPR84
Although blockade of GPR84 may potentially prove effective also in diseases associated with inflammation
- GPCR Therapeutics Expands Scientific Advisory Board
May 2022 "Seoul, South Korea, 28 April 2022 – GPCR therapeutics, Inc., a venture-backed clinical stage
- Nanobodies as Probes and Modulators of Cardiovascular G Protein-Coupled Receptors
We also discuss how advancing technologies to discover nanobodies with tailored specificities may expand
- Cholesterol occupies the lipid translocation pathway to block phospholipid scrambling by a GPCR
This mechanism may explain the inability of GPCRs to scramble lipids at the plasma membrane."
- A central alarm system that gates multi-sensory innate threat cues to the amygdala
The identification of unified innate threat pathways may provide insights into developing therapeutic
- Drug Discovery Picks Up the Pace, Stays on Target
A project to develop a perfect drug, or a drug that is as safe and effective as possible, may never begin