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Results found for "Dr. Thomas P. Sakmar"

  • Pharmacological Properties and Function of PxOctβ3 Octopamine Receptor in Plutella xylostella (L.)

    and an analysis using quantitative PCR showed that it was expressed at all developmental stages of P. of double-stranded RNA in an RNA interference assay indicated that PxOctβ3 regulates development in P. This study demonstrated the pharmacological properties and functions of PxOctβ3 in P. xylostella, thus

  • 📰 Breaking Down the Latest GPCR Discoveries: a Weekly Update (Nov 27-Dec 3, 2023)

    This week's highlight: Dr. November Dr. GPCR Newsletter is out now. Subscribe for this month's video featuring Dr. Ensure to catch the upcoming episodes of Dr. GPCR Podcast featuring Dr. Neil Grimsey and Dr. Researcher Post-Doctoral Fellow Sr Scientist in Obesity, Muscle, and Metabolism Post-Doctoral Fellow Explore Dr

  • 📰 GPCR Weekly News, November 20 to 26, 2023

    This week's highlight: Thank you to Dr. Molecular Sensing in Adhesion GPCR Dissociation Physiological Force Modulation in Drosophila Neurons Dr Our November Dr. GPCR Newsletter is now available. This month's video newsletter features Dr. Don't miss the upcoming episodes of Dr.GPCR Podcast featuring Dr. Neil Grimsey and Dr. Fellow Research Associate I, Tissue Culture Post-Doc Research Associate Postdoctoral Fellow Explore Dr

  • Nanobodies: New Dimensions in GPCR Signaling Research

    J., Pardon, E., Casarosa, P., Chae, P. S., Devree, B. T., Rosenbaum, D. M., Thian, F. M., Manglik, A., Hu, J., Hu, K., Eitel, K., Hübner, H., Pardon, E., Valant, C., Sexton, P. C., Gmeiner, P., Steyaert, J., Weis, W. I., Garcia, K. C., Wess, J., & Kobilka, B. K. (2013). D., Tworak, A., Watanabe, K., Pardon, E., Steyaert, J., Kandori, H., Katayama, K., Kiser, P.

  • 📰 GPCR Weekly News, September 4 to 10, 2023

    This week's highlights: Dr. Yamina Berchiche, Founder and Director of Dr. Dr. Dr. Save these dates: September 22: Join us for the Dr. Subscribe to the Dr. GPCR Newsletter for more insights!

  • 📰 GPCR Weekly News, March 18 to 24, 2024

    This week's highlight includes congrats to: DrsDr. GPCR Symposia With a premium membership, you can watch on-demand the Dr. Dr. Behavior Director of Laboratory Operations - Single-molecule Imaging Center Scientific Assistant Join Dr

  • Pharmacologic Models

    Ecosystem Premium Members: Look for significant savings on this and other resources in your weekly Dr

  • Decoding Schild Analysis: The Pharmacologist’s Lens on Competitive Antagonism

    In the full lecture, Dr. Linearity  of the Schild regression (log(DR–1) vs. antagonist concentration). As Dr. Watch the course trailer 👇 Why Terry’s Corner Weekly pharmacology lectures by Dr.

  • Enzyme Inhibition Pharmacology: The Hidden Gatekeepers of GPCR Drug Discovery

    🎥  Coming Soon: Live AMA with Dr. Terry Kenakin This Month’s Live AMA — October 30 at 12 PM EST Join Dr. course topics Weekly new releases  — always fresh, always relevant Live monthly AMA  sessions with Dr , pharma, and academia 💎 $2999/year — one conference cost = a full year of expert training Premium Dr Monthly AMAs  where you can challenge Dr. Kenakin with your own enzyme or GPCR interaction puzzles.

  • Exploring the Breakthroughs in GPCR Research

    This week's highlight includes congrats to: Remi Janicot, and Dr. on the Relevance of GPCR dynamics for receptor activation, signalling bias and allosteric modulation Drs study on the Role of the V2R-βarrestin-Gβγ complex in promoting G protein translocation to endosomes Dr GPCR University We are excited to announce the dates for our upcoming courses led by Dr. Director GPCR Drug Discovery Biologist Post-Doctoral Scientist- Molecular Pharmacology (FDE) Join Dr.

  • 📰 GPCR Weekly News, July 3 to 9, 2023

    Congratulations to Dr. Don't forget to mark your calendars for July 21st, as the upcoming Dr. Be sure to subscribe to Dr. GPCR Newsletter for updates! Industry News Dr. Associate Director / Director, Clinical Operations Professor in Cardiovascular Pharmacology Explore Dr

  • Unveiling GPCR Priming: The Hidden Synergy in Cellular Signalling

    Proc Natl Acad Sci U S A, 2020. 117(35): p. 21723-21730. 2.      Proceedings of the National Academy of Sciences, 2017. 114(14): p. 3756-3761. 3.      Mol Pharmacol, 2017. 91(5): p. 533-544.

  • The Perils and Guardrails of Modifying Signalling Proteins in Bioassays

    Dr. Hunter P. Persechino M, Hedderich JB, Kolb P, Hilger D. Changeux J-P, Christopoulos A. González-Maeso J, Weisstaub NV, Zhou M, Chan P, Ivic L, Ang R, et al.

  • 📰 GPCR Weekly News, August 7 to 13, 2023

    On September 22nd, we're hosting the Dr. GPCR Symposium on 'GPCRs as Therapeutic Modalities'. Make sure to stay in the loop with the Dr. GPCR Newsletter! Molecular Pharmacology Director, Clinical Data Management Director, Discovery Toxicology Postdoc Fellow - Dr Robert Lefkowitz Lab Postdoc Fellow - Dr. Robert Lefkowitz Lab Explore Dr. GPCR Ecosystem

  • Misread the Curve, Misjudge the Drug: Rethinking Antagonism in GPCR Pharmacology

    This week in Terry’s Corner, Dr. DR curves shift to the right with no loss of maximal effect. Each subscription includes: Weekly deep dives from Dr.

  • Beyond Clearance: The Strategic Power of Irreversible Drug Binding

    🎥 Next Week's Release: The First AMA Session The first Ask-Me-Anything with Dr. course topics Weekly new releases  — always fresh, always relevant Live monthly AMA  sessions with Dr , pharma, and academia 💎 $2999/year — one conference cost = a full year of expert training Premium Dr Monthly AMAs  where you can challenge Dr. Kenakin with your own enzyme or GPCR interaction puzzles.

  • Unlock the Hidden Complexity Behind GPCRs—From Terry Kenakin’s Vault

    In the foundational lesson of Terry’s Corner , Dr.

  • GPCR News Flash! Top Updates You Can't-Miss! + University CheatSheet is finally available! ❄ Dec 2 - 8, 2024

    It's starting to look a lot like Christmas at Dr. GPCR! coupling between extracellular and transmembrane domains modulates holo-adhesion GPCR function Szymon P

  • GPCR Therapeutics Expands Scientific Advisory Board

    Dr. Michel Bouvier, Dr. Luisa Salter-Cid, Dr. Omar Nadeem and Dr.

  • 🎄 Have Yourself a Merry Little GPCRmas! ❄ Dec 9 - 15, 2024

    At Dr. Thank you for sharing your perspective and helping us shape the future of the Dr. GPCR ecosystem! Best, Yamina & the Dr.

  • 🧠Do you want to share your #GPCR knowledge?

    Come to Dr. GPCR Ecosystem and create a course on your favorite #GPCR research, technique and more… Available for Dr

  • Sign Up Now!

    The program of the Dr. GPCR Summit from October 10th to the 16th is taking shape. Check it out today but first become a Dr. GPCR Ecosystem site member, which is free!

  • An overview of the compartmentalized GPCR Signaling: Relevance and Implications

    P. (2009). Sustained cyclic AMP production by parathyroid hormone receptor endocytosis. https://doi.org/10.1210/en.2015-1945 Irannejad, R., Pessino, V., Mika, D., Huang, B., Wedegaertner, P. I., Gerrikagoitia, I., Suarez, J., Rodríguez De Fonseca, F., Puente, N., Marsicano, G., & Grandes, P. Frontiers in physiology, 7, 476. https://doi.org/10.3389/fphys.2016.00476 Insel, P. P., Lowy, A. M., & Murray, F. (2018).

  • 📰 GPCR Weekly News, August 21 to 27, 2023

    This week's highlights: Dr. Terence E. Protein-Biased Agonists for Intracellular Angiotensin Receptors Promote Collagen Secretion in Myofibroblasts' Dr September 22: Don't miss the Dr. GPCR Symposium on 'GPCRs as Therapeutic Modalities'. Subscribe to Dr. GPCR Newsletter to receive more insights! Director, Regulatory Affairs Research Scientist/Senior Scientist I - Molecular Pharmacology Explore Dr

  • 📰 GPCR Weekly News, September 25 to October 1, 2023

    This week's highlights: Drs. Dr. Did you know that as a premium member, you enjoy exclusive access to recorded talks from our Dr. Subscribe now to gain access to exclusive insights from Dr. GPCR Newsletter! Research Fellow Research Technician II - Surgery Post-Doc Research Associate Research Technician Explore Dr

  • 📰 GPCR Weekly News, October 23 to 29, 2023

    Save the dates: November 17: Join our final Dr. Get the inside scoop by subscribing to our monthly Dr. GPCR Newsletter, and watch our latest video featuring Dr. Kathleen Caron. Pharmaceuticals In vivo Antibody Discovery Research Scientist In Vitro Biologist/Molecular Pharmacologist Explore Dr

  • 📰 GPCR Weekly News, July 10 to 16, 2023

    This week's GPCR papers feature a publication by Dr. Robert J Lefkowitz. Join us tomorrow, July 21, in the Dr. Remember to subscribe to Dr. GPCR Newsletter for updates! Lab Clinical Trial Associate Research Scientist/Senior Scientist I - Molecular Pharmacology Explore Dr

  • 📰 GPCR Weekly News, May 1 to 7, 2023

    Save the date and join us next week, May 19th, 2023 for the Dr. Stay informed with the latest Dr. GPCR News by subscribing to our monthly newsletter. 2023 Neurocrine Biosciences Reports First Quarter 2023 Financial Results Find Therapeutics welcomes Dr Expectations, EPS Lags “As Precision Medicine is critical, we cannot think about one size fits all” Dr Scientist—Immuno-Oncology Convergent Research - Senior Scientist, Cell-Based Assay Development Explore Dr

  • 📰 GPCR Weekly News, June 5 to 11, 2023

    This week's GPCR papers feature publications from Drs. attention to some of our events and resources: Please mark your calendars for July 21st for our next Dr Stay updated with Dr. GPCR News by subscribing to our monthly newsletter. Our founder Dr. Yamina A. Associate Director / Director, Clinical Operations Postdoctoral Research Associate Lab Manager Explore Dr

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