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Results found for "G. Aditya Kumar"
- Septerna emerges with $100M to spark 'second golden age' of prolific drug target GPCR with ...
GPCR with pioneer as co-founder "Jan 27, 2022 07:00am Septerna wants to spark a second golden age in G-protein-coupled
- Mechanism of enhanced sensitivity of mutated β-adrenergic-like octopamine receptor to amitraz in...
Previous assays verified that a typical G protein-coupled receptor, β-adrenergic-like octopamine receptor
- GRK2 selectively attenuates the neutrophil NADPH-oxidase response triggered by β-arrestin recruiting
avoid a prolonged pro-inflammatory neutrophil response, signaling downstream of an agonist-activated G
- Emerging approaches for decoding neuropeptide transmission
includes their post-translational processing, release from dense core vesicles, and ability to activate G-protein-coupled
- Opioid Ligands Addressing Unconventional Binding Sites and More Than One Opioid Receptor Subtype
August 2022 "Opioid receptors (ORs) represent one of the most significant groups of G-protein coupled
- 📰 GPCR Weekly News, April 17 to 23, 2023
Regulation of the pro-inflammatory G protein-coupled receptor GPR84. GPCRs in Neuroscience G protein coupled receptors as targets for transformative neuropsychiatric therapeutics
- The Quiet Power of RGS Proteins: Rethinking Pain Pathways through GPCR Biology
Alex Serafini pointed out in his interview, Regulators of G protein Signaling (RGS proteins) might
- Lysosomal GPCR-like protein LYCHOS signals cholesterol sufficiency to mTORC1
lysosomal proteomes, we identified lysosomal cholesterol signaling (LYCHOS, previously annotated as G
- Developing the Cannabinoid Receptor 2 (CB2) pharmacopoeia: past, present, and future
October 2022 "Cannabinoid Receptor 2 (CB2) is a G protein-coupled receptor (GPCR) with considerable,
- Developing the Cannabinoid Receptor 2 (CB2) pharmacopeia: past, present, and future
August 2022 "Cannabinoid Receptor 2 (CB2) is a G protein-coupled receptor (GPCR) with considerable, though
- Posttranslational modifications in GPCR internalization
August 2022 "G protein-coupled receptors (GPCRs) are the largest family of membrane receptors that serve
- Molecular basis for ligand modulation of the cannabinoid CB 1 receptor
August 2022 "The cannabinoid CB1 receptor is the most abundant G protein coupled receptor (GPCR) in
- 📰 GPCR Weekly News, April 1 to 7, 2024
through the μ opioid receptor GPCR Binders, Drugs, and more Predicting associations between drugs and G and Exhibition June 2 - 7, 2024 | Chemotactic Cytokines June 9 - 14, 2024 | 2024 Phosphorylation and G-Protein
- GPCR Therapeutics Expands Scientific Advisory Board
international biopharmaceutical company with an innovative approach to drug discovery based on targeting G
- Domain Therapeutics Raises $42m Series A Financing
biopharmaceutical company specializing in the research and development of innovative drugs targeting G
- 📰 GPCR Weekly News
GPCRs in Oncology and Immunology Pan-cancer functional analysis of somatic mutations in G protein-coupled Deadline February 12, 2023 Current Technologies To Understand G-Protein-Coupled Receptor Molecular Pharmacology
- Dr. GPCR and Celtarys Research Join Forces to Expand Access to Innovative GPCR Tools
GPCR, the global knowledge hub for G protein-coupled receptor (GPCR) research and education, is proud
- Chemerin Forms: Their Generation and Activity
Chemerin can signal via two G protein-coupled receptors, chem1 and chem2, as well as be bound to a third
- 📰 GPCR Weekly News, March 4 to 10, 2024
/o protein responses of some native GPCRs in neurons Beyond the Nucleus: Plastic Chemicals Activate G and Exhibition June 2 - 7, 2024 | Chemotactic Cytokines June 9 - 14, 2024 | 2024 Phosphorylation and G-Protein
- High hedgehog signaling is transduced by a multikinase-dependent switch controlling the...
multikinase-dependent switch controlling the apico-basal distribution of the GPCR smoothened "The oncogenic G-protein-coupled
- Adenosine receptor signalling in Alzheimer's disease
Emerging evidence suggests adenosine G protein-coupled receptors (GPCRs) are promising therapeutic targets
- Adenosine receptor signalling in Alzheimer's disease
Emerging evidence suggests adenosine G protein-coupled receptors (GPCRs) are promising therapeutic targets
- GPR110, a receptor for synaptamide, expressed in osteoclasts negatively regulates osteoclastogenesis
Although some G-protein coupled receptors (GPCRs) were reported to play roles in osteoblast function,
- TAS2R supports odontoblastic differentiation of human dental pulp stem cells in the inflammatory...
The G protein and intracellular Ca2+ were detected, respectively, by qPCR and Fluo-4AM Ca2+ fluorescent
- Isoform-and ligand-specific modulation of adhesion GPCR ADGRL3/Latrophilin3 by a synthetic binder
September 2022 "Adhesion G protein-coupled receptors (aGPCRs) are cell-surface proteins with large extracellular
- Allosteric Effect of Nanobody Binding on Ligand-Specific Active States of the β2 Adrenergic Receptor
Nanobody binding stabilizes G-protein-coupled receptors (GPCR) in a fully active state and modulates binding site and the extracellular domains in conformations modulated by a full agonist, BI167107, and a G-protein-biased
- Discovery and In Vivo Evaluation of ACT-660602: A Potent and Selective Antagonist of the Chemokine..
Chemokine Receptor CXCR3 for Autoimmune Diseases "The chemokine receptor CXCR3 is a seven-transmembrane G-protein-coupled
- Targeting CXCR1 and CXCR2 receptors in cardiovascular diseases
Numerous intracellular mediators are activated by these G protein-coupled receptors based on several
- Endogenous ligand recognition and structural transition of a human PTH receptor
PTH-related peptide (PTHrP) bind to the parathyroid hormone receptor 1 (PTH1R) and activate the stimulatory G-protein
- Label-free LC-MS based assay to characterize small molecule compound binding to cells
In one example, to study a G protein coupled receptor (GPCR), we used one antagonist as probe and multiple


