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Results found for "opioid pharmacology"
- Xylazine, Fentanyl, and the Fight for Breath with Catherine Demery | Dr. GPCR Ecosystem
How GPCR pharmacology connects molecular insights to real-world interventions. how fentanyl and xylazine shut down breathing through different mechanisms—work that blends receptor pharmacology now and see how one scientist is turning molecules into a mission, bridging the gap between receptor pharmacology GPCR ecosystem , GPCR training program , GPCR podcast , opioid pharmacology , xylazine research , mu opioid receptor , pharmacogenomics , fentanyl epidemic , preclinical pharmacology Enjoying the Dr.
- From Curiosity to Breakthrough: Ajay Yekkirala on GPCR Innovation | Dr. GPCR Ecosystem
Ajay Yekkirala is a GPCR pharmacologist, biotech entrepreneur, and co-founder of Superluminal Medicines strategic leaders seeking new drug development models Anyone curious about where AI meets molecular pharmacology /PhD, a rejection letter pivoted him into a PhD program at the University of Iowa, where he studied opioid pharmacology under the legendary Dr. Driven by the opioid crisis and the lack of non-addictive pain treatments, Ajay co-founded Blue Therapeutics
- Regulation and role of mitochondria delta opioid receptors
Committee Sponsors GPCR Retreat Program < Back to schedule Regulation and role of mitochondria delta opioid Soon About Louis Gendron "Dr Louis Gendron, PhD is tenured Professor and Chair of the Department of Pharmacology-Physiology He has 20+ years of experience in in vitro and in vivo GPCR pharmacology and has published seminal papers where he used various approaches to describe the role of opioid receptors in pain and anagesia as well as to study the mechanisms involved in the cellular trafficking of the delta opioid receptor.
- Can we preserve opioid pain relief without the side effects? 🔬 On Ep.166 of the Dr.GPCR Podcast, Ben Clements shares how positive allosteric modulators (PAMs) at the mu-opioid receptor could revolutionize treatment —with a 10x boost in methadone efficacy. Tune in for a masterclass on translational pharmacology, curiosity-driven science, and meaningful mentorship. 🎧 Full episode: Ep 166 with Dr. Ben Clements #GPCRresearch #DrGPCR #GPCRpodcast #OpioidPharmacology #DrugDiscovery | Dr. GPCR Ecosystem
Home → Flash News → Can we preserve opioid pain relief without the side effects? .166 of the Dr.GPCR Podcast, Ben Clements shares how positive allosteric modulators (PAMs) at the mu-opioid Tune in for a masterclass on translational pharmacology, curiosity-driven science, and meaningful mentorship GPCR Podcast Can we preserve opioid pain relief without the side effects? Tune in for a masterclass on translational pharmacology, curiosity-driven science, and meaningful mentorship
- Dr. Mark Connor | Dr. GPCR Ecosystem
Mark Connor Undergraduate BSc with Honours in Pharmacology from University of Sydney (1987, snake neurotoxins ), Ph.D. from Department of Pharmacology, University of Washington (1992, mentor Charley Chavkin , sigma Postdoc with Graeme Henderson (Bristol, opioids and Ca signaling) and Mac Christie (Sydney, opioids in and T-type Ca channels) and Brain and Mind Research Institute (Sydney). 2009, appointed Professor of Pharmacology Currently pursuing molecular pharmacology of phytocannabinoids and novel synthetic cannabinoids, with
- When to Walk, When to Run: Lessons from the GPCR Trenches with Dr. Ben Clements | Dr. GPCR Ecosystem
postdoctoral fellow at the University of Michigan, joins the conversation as a rising voice in GPCR pharmacology GPCRs and the Opioid Crisis: A New Pharmacological Frontier Now at the University of Michigan, Ben focuses Scientific Rigor: The Value of ‘Old School’ Pharmacology Despite the availability of modern tools, Ben Using site-directed mutagenesis and pharmacological synergy assays , his team aims to understand how This project involves molecular pharmacology in cell models to determine binding sites and mechanisms
- Dr. John Streicher | Dr. GPCR Ecosystem
John Streicher from the department of pharmacology at the University of Arizona. Today, John and his team focus on understanding how signal transduction cascades downstream of the opioid receptors work, including the unique organization of chaperone protein Hsp90 modulation of opioid signaling John Streicher on the web University of Arizona Department of Pharmacology Google Scholar Pubmed LinkedIn
- Dr. Graciela Pineyro | Dr. GPCR Ecosystem
Graciela Pineyro is a professor of pharmacology at the department of pharmacology and physiology of the She has done extensive work on the molecular pharmacology of opioid receptors and is currently focusing on the pharmacology of cannabinoids in the context of pain.
- Dr. Graciela Pineyro | Dr. GPCR Ecosystem
Graciela Pineyro’s love for GPCR pharmacology started in Uruguay where she first worked on the serotonin This interest in research and pharmacology took Graciela to Canada where she stayed ever since she arrived Graciela has done extensive work on the molecular pharmacology of opioid receptors, exploring their signaling Today, Graciela and her team’s efforts are directed towards the characterization of the pharmacological
- Dopamine-Mediated Motor Recovery after Ischemic Stroke
graduate research on the regulation of axonal transport by tricyclic antidepressants (M.Sc.) and molecular pharmacology of opioid receptors (Ph.D.) in the Department of Pharmacology at the Université de Montréal under the The Tiberi Lab pursues the study of the molecular, structural, pharmacological and signaling features
- Check out the new optical BRET-based biosensor, Gαi bONE-GO! In neuronal cell lines, the use of Gαi bONE-GO revealed that several natural opioid neuropeptides act as partial agonists, contrary to their previous characterization as full agonists. Check out the latest GPCR news in the Ecosystem today! You’ll need to register but don’t worry, it’s Free! ➡️https://buff.ly/e6gAlBv #gpcr#drgpcr | Dr. GPCR Ecosystem
In neuronal cell lines, the use of Gαi bONE-GO revealed that several natural opioid neuropeptides act In neuronal cell lines, the use of Gαi bONE-GO revealed that several natural opioid neuropeptides act
- “Research is all about knowing when to walk and when to run.” –Ben Clements In Ep. 166 of the Dr.GPCR Podcast, hear how a postdoc is reshaping the conversation on opioid use, imposter syndrome, and the power of collaborative science. Why early-career voices are critical in GPCR drug discovery —and how lab culture makes all the difference. 🎧 Watch here: https://buff.ly/Kr3qKud #GPCRresearch #DrGPCR #GPCRpodcast #OpioidPharmacology #DrugDiscovery | Dr. GPCR Ecosystem
Ben Clements In Ep. 166 of the Dr.GPCR Podcast, hear how a postdoc is reshaping the conversation on opioid Ben Clements In Ep. 166 of the Dr.GPCR Podcast, hear how a postdoc is reshaping the conversation on opioid
- Dr. Amynah Pradhan | Dr. GPCR Ecosystem
Paul Clarck , where she studied opioid receptors. She then returned to academia and worked on opioids as a postdoctoral trainee with Dr. Brigitte Kieffer , where she studied ligand-directed signaling at the delta-opioid receptor. Amynah studied how arrestins regulate ligand-directed signaling at delta-opioid receptors, and it is Andrew Charles that who specialized in animal models of migraine and delta-opioid receptors as a therapeutic
- Dr. Lauren M. Slosky | Dr. GPCR Ecosystem
Slosky Lauren Slosky is an Assistant Professor in the Department of Pharmacology and a member of the She received a Ph.D. in Medical Pharmacology from The University of Arizona in 2015 and completed a postdoctoral Integrating GPCR biology, behavioral pharmacology, and systems neuroscience approaches, the Slosky Lab selectivity can be leveraged in the development of safe and effective treatments for stimulant and opioid She is currently a faculty trainer for the University of Minnesota's MS and Ph.D. programs in Pharmacology
- Dr. Kathryn E Livingston | Dr. GPCR Ecosystem
Kathryn obtained her BS in Chemistry from Carnegie Mellon University and went on to receive a Ph.D. in Pharmacology John Traynor , Kathryn worked to develop and understand first-in-class allosteric modulators of opioid
- Trainee Symposium I
GPCR Title: Characterization of Novel Opioid-Neurotensin Bifunctional Ligands Designed to Target Pain Management About Émile Breault "Emile Breault is undertaking his master's degree in pharmacology at He recently received his BSc in pharmacology from the University of Sherbrooke in 2023.
- Irfan Dhanidina, Dr. Kathleen Caron and Dr. Lauren Slosky | Dr. GPCR Ecosystem
Caron is also past Associate Editor at JCI and served as the inaugural Associate Editor at ACS-Pharmacology Lauren Slosky "Lauren Slosky is an Assistant Professor in the Department of Pharmacology and a member Integrating GPCR biology, behavioral pharmacology, and systems neuroscience approaches, the Slosky Lab selectivity can be leveraged in the development of safe and effective treatments for stimulant and opioid She is currently a faculty trainer for the University of Minnesota's MS and Ph.D. programs in Pharmacology
- Complex Allosteric Cannabinoid Receptor Pharmacology
Committee Sponsors GPCR Retreat Program < Back to schedule Complex Allosteric Cannabinoid Receptor Pharmacology Robert and his lab have been interested in the molecular pharmacology of cannabinoids for nearly 10 years
- GPCR Courses
premium to get access The Practical Assessment of Signaling Bias Signaling bias is an inherent feature of pharmacology Yamina Berchiche 🔒 Premium Content Watch recording Applying Pharmacology to Drug Discovery Class 1 - Fundamentals of Pharmacology Class 2 - Characterizing Agonists Class 3 - Characterizing Antagonists and biased agonism Class 3 - Antagonist pharmacology and binding assay analysis Class 4 - New dimensions Also super-valuable for those of us learning how to teach pharmacology Anonymous Dr.
- Unlock your pharmacology potential with Terry’s Corner. No fluff. Just clear, on-demand insight from Dr. Terry Kenakin—built for scientists at every level. 🟢 Building core expertise? Learn dose-response, agonism, binding, bias, kinetics, and the models that build real confidence. 🟢 Driving drug discovery? Apply pharmacology to selectivity, ADME, early safety, and smarter decision-making. 🟢 Already a drug hunter? Sharpen your edge with allosteric modulation, residence time, molecular dynamics, and translational PK/PD. Learn on-demand. Apply immediately. Early access begins July 1 → https://www.terrykenakin.com #pharmacology #GPCRscience #drugdiscovery #TerrysCorner #biotechtraining | Dr. GPCR Ecosystem
Home → Flash News → Unlock your pharmacology potential with Terry’s Corner. No fluff. Apply pharmacology to selectivity, ADME, early safety, and smarter decision-making. 🟢 Already a drug Early access begins July 1 → https://www.terrykenakin.com #pharmacology #GPCRscience #drugdiscovery # Apply pharmacology to selectivity, ADME, early safety, and smarter decision-making. 🟢 Already a drug Early access begins July 1 → https://www.terrykenakin.com #pharmacology #GPCRscience #drugdiscovery #
- What’s one key piece of advice from Ian Chronis in Ep.164 of the Dr.GPCR Podcast?Listen to other scientists’ research—it’s a great way to stay motivated and inspired 🚀 Don’t miss this insightful conversation on GPCRs, pharmacology, and scientific discovery! ✅ https://buff.ly/FTB69y9 #GPCR #DrGPCR #SciencePodcast #Pharmacology #CancerResearch | Dr. GPCR Ecosystem
research—it’s a great way to stay motivated and inspired 🚀 Don’t miss this insightful conversation on GPCRs, pharmacology ✅ https://buff.ly/FTB69y9 #GPCR #DrGPCR #SciencePodcast #Pharmacology #CancerResearch Published on April research—it’s a great way to stay motivated and inspired 🚀 Don’t miss this insightful conversation on GPCRs, pharmacology ✅ https://buff.ly/FTB69y9 #GPCR #DrGPCR #SciencePodcast #Pharmacology #CancerResearch Previous Next Recent
- 📢 All 2025 Dr.GPCR Courses Are Open for Registration! Which one will you choose? 🚀 Whether you're diving into GPCR drug discovery, pharmacology, or advanced modeling, there's a course for you. 💡 Bonus: Premium Members enjoy 25% off on all courses! 🔗 Explore & register today: https://www.ecosystem.drgpcr.com/gpcr-courses #GPCR #DrGPCR #Biotech #DrugDiscovery #Pharmacology | Dr. GPCR Ecosystem
🚀 Whether you're diving into GPCR drug discovery, pharmacology, or advanced modeling, there's a course register today: https://www.ecosystem.drgpcr.com/gpcr-courses #GPCR #DrGPCR #Biotech #DrugDiscovery #Pharmacology 🚀 Whether you're diving into GPCR drug discovery, pharmacology, or advanced modeling, there's a course register today: https://www.ecosystem.drgpcr.com/gpcr-courses #GPCR #DrGPCR #Biotech #DrugDiscovery #Pharmacology
- Applying Pharmacology to Drug Discovery | Dr. GPCR Ecosystem
Applying Pharmacology to Drug Discovery Dr.
- 🎧 "You will always feel like you know nothing— and that’s completely fine." In Ep.162 of the Dr.GPCR Podcast, Dr. Gabriele Kockelkoren shares: 🔬 How GPCR spatial organization shapes signaling and drug responses 🌍 His interdisciplinary journey from physics to pharmacology 💡 Why embracing the unknown is key to scientific breakthroughs A must-listen for biophysicists, pharmacologists, and drug hunters pushing the boundaries of discovery! 🎙️ Tune in now:Ep 162 with Dr. Gabriele Kockelkoren #DrGPCR #GPCR #Biophysics #Pharmacology #DrugDiscovery #SciencePodcast | Dr. GPCR Ecosystem
spatial organization shapes signaling and drug responses 🌍 His interdisciplinary journey from physics to pharmacology 💡 Why embracing the unknown is key to scientific breakthroughs A must-listen for biophysicists, pharmacologists Gabriele Kockelkoren #DrGPCR #GPCR #Biophysics #Pharmacology #DrugDiscovery #SciencePodcast Published spatial organization shapes signaling and drug responses🌍 His interdisciplinary journey from physics to pharmacology Gabriele Kockelkoren #DrGPCR #GPCR #Biophysics #Pharmacology #DrugDiscovery #SciencePodcast Previous
- Session I | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Departments of Psychiatry and Molecular Pharmacology and Therapeutics, Columbia University Vagelos College As an undergraduate, he studied opioid receptor trafficking and G protein conformational dynamics in Tall Department of Pharmacology, University of Michigan "" About Frank Kwarcinski "I am research faculty within the department of Pharmacology at the University of Michigan.
- 🔬 Enhance Your GPCR Expertise with Dr.GPCR University! Looking to sharpen your skills in GPCR pharmacology, drug discovery, data analysis, or project management? Dr.GPCR University offers industry-focused courses designed to help you stay ahead in the field. ✅ Comprehensive course library covering cutting-edge GPCR science ✅ Practical insights for real-world drug discovery challenges ✅ Flexible, on-demand learning to fit your schedule 🚀 Elevate your expertise today: Start learning now #GPCR #Pharmacology #DrugDiscovery #Biotech #DrGPCR | Dr. GPCR Ecosystem
Looking to sharpen your skills in GPCR pharmacology, drug discovery, data analysis, or project management on-demand learning to fit your schedule 🚀 Elevate your expertise today: Start learning now #GPCR #Pharmacology Looking to sharpen your skills in GPCR pharmacology, drug discovery, data analysis, or project management on-demand learning to fit your schedule 🚀 Elevate your expertise today: Start learning now #GPCR #Pharmacology
- 10 GPCR pharmacology lessons. Zero fluff. Launching July 1, Terry’s Corner gives you the clarity and confidence to make better decisions—starting with: • The role of pharmacology in discovery strategy • Black & Leff’s operational model—finally made practical • Binding curves, orthosteric vs allosteric function, and real vs apparent affinity • Molecular dynamics and how they guide ligand design • Why Terry built this—and how it sharpens your next move 📅 Learn anytime. New course every week. 📬 Subscribe to The Kenakin Brief → https://www.terrykenakin.com #GPCRscience #drugdiscovery #TerrysCorner #GPCRpharmacology #ligandbinding | Dr. GPCR Ecosystem
Home → Flash News → 10 GPCR pharmacology lessons. Zero fluff. s Corner gives you the clarity and confidence to make better decisions—starting with: • The role of pharmacology TerrysCorner #GPCRpharmacology #ligandbinding Published on June 30, 2025 Category Terry's Corner 10 GPCR pharmacology Corner gives you the clarity and confidence to make better decisions—starting with: 🟢 The role of pharmacology
- pharmacology at your fingertips terrys corner launches | Dr. GPCR Ecosystem
Home → Flash News → pharmacology at your fingertips terrys corner launches Published on July 4, 2025 Category GPCR Weekly News Stronger pharmacology drives smarter decisions in GPCR discovery. strategies Unlock deeper insight—starting now. ➡️ Read the newsletter: https://www.ecosystem.drgpcr.com/post/pharmacology-at-your-fingertips-terry-s-corner-launches #DrGPCR #GPCR #DrugDiscovery #pharmacology #biotechnews #terrykenakin #GPCRconsulting Previous Next
- Terry's Corner is Officially LIVE! 🎉 This is your new go-to for mastering drug discovery pharmacology. No fluff, just clear, on-demand insights from Terry Kenakin. Building core expertise? Master dose-response, binding, kinetics, and foundational models. Driving drug discovery? Apply pharmacology to selectivity, ADME, and strategic decision-making. An experienced drug hunter? Sharpen your edge with allosteric bias, residence time, and translational PK/PD. Learn on-demand, apply immediately: https://terrykenakin.com #DrGPCR #GPCR #pharmacology #TerrysCorner #DrugDiscovery | Dr. GPCR Ecosystem
🎉 This is your new go-to for mastering drug discovery pharmacology. Apply pharmacology to selectivity, ADME, and strategic decision-making. An experienced drug hunter? Learn on-demand, apply immediately: https://terrykenakin.com #DrGPCR #GPCR #pharmacology #TerrysCorner 🎉 This is your new go-to for mastering drug discovery pharmacology. Apply pharmacology to selectivity, ADME, and strategic decision-making. An experienced drug hunter?
- master gpcr pharmacologic models before its too late | Dr. GPCR Ecosystem
Home → Flash News → master gpcr pharmacologic models before its too late Published on July 11, 2025 Category Terry’s Corner breaks down the 4 pharmacologic models that separate forecasting from guessing. Dr. utm_content=bufferd9b30&utm_medium=social&utm_source=twitter.com&utm_campaign=buffer #GPCR #Pharmacology

















